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References

  • 1
    Brisson LF, Tenhaken R & Lamb C (1994) Function of oxidative cross-linking of cell wall structural proteins in plant disease resistance. Plant Cell 6, 17031712.
  • 2
    Abramovitch RB & Martin GB (2004) Strategies used by bacterial pathogens to suppress plant defenses. Curr Opin Plant Biol 7, 356364.
  • 3
    Morrissey JP & Osbourn AE (1999) Fungal resistance to plant antibiotics as a mechanism of pathogenesis. Microbiol Mol Biol Rev 63, 708724.
  • 4
    Mysore KS & Ryu CM (2004) Nonhost resistance: how much do we know? Trends Plant Sci 9, 97104.
  • 5
    Dangl JL, Dietrich RA & Richberg MH (1996) Death don't have no mercy: cell death programs in plant–microbe interactions. Plant Cell 8, 17931807.
  • 6
    Greenberg JT (1996) Programmed cell death: a way of life for plants. Proc Natl Acad Sci USA 93, 1209412097.
  • 7
    van Doorn WG & Woltering EJ (2005) Many ways to exit? Cell death categories in plants. Trends Plant Sci 10, 117122.
  • 8
    Hofius D, Tsitsigiannis DI, Jones JD & Mundy J (2007) Inducible cell death in plant immunity. Semin Cancer Biol 17, 166187.
  • 9
    Hammond-Kosack KE & Jones JD (1996) Resistance gene-dependent plant defense responses. Plant Cell 8, 17731791.
  • 10
    Van Loon LC, Pierpoint WS, Boller T & Conejero V (1994) Recommendations for naming plant pathogenesis-related proteins. Plant Mol Biol Rep 12, 245264.
  • 11
    Markovic-Housley Z, Degano M, Lamba D, von Roepenack-Lahaye E, Clemens S, Susani M, Ferreira F, Scheiner O & Breiteneder H (2003) Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier. J Mol Biol 325, 123133.
  • 12
    Okushima Y, Koizumi N, Kusano T & Sano H (2000) Secreted proteins of tobacco cultured BY2 cells: identification of a new member of pathogenesis-related proteins. Plant Mol Biol 42, 479488.
  • 13
    Sels J, Mathys J, De Coninck BM, Cammue BP & De Bolle MF (2008) Plant pathogenesis-related (PR) proteins: a focus on PR peptides. Plant Physiol Biochem 46, 941950.
  • 14
    Breiteneder H (2004) Thaumatin-like proteins – a new family of pollen and fruit allergens. Allergy 59, 479481.
  • 15
    Crowell DN, John ME, Russell D & Amasino RM (1992) Characterization of a stress-induced, developmentally regulated gene family from soybean. Plant Mol Biol 18, 459466.
  • 16
    Breda C, Sallaud C, el-Turk J, Buffard D, de Kozak I, Esnault R & Kondorosi A (1996) Defense reaction in Medicago sativa: a gene encoding a class 10 PR protein is expressed in vascular bundles. Mol Plant Microbe Interact 9, 713719.
  • 17
    Sikorski MM, Biesiadka J, Kasperska AE, Kopcinska J, Lotocka B, Golinowski W & Legocki AB (1999) Expression of genes encoding PR10 class pathogenesis-related proteins is inhibited in yellow lupine root nodules. Plant Sci 149, 125137.
  • 18
    Tokuriki N & Tawfik DS (2009) Protein dynamism and evolvability. Science 324, 203207.
  • 19
    Tokuriki N & Tawfik DS (2009) Stability effects of mutations and protein evolvability. Curr Opin Struct Biol 19, 596604.
  • 20
    Franco OL (2011) Peptide promiscuity: an evolutionary concept for plant defense. FEBS Lett 585, 9951000.
  • 21
    Colditz F, Niehaus K & Krajinski F (2007) Silencing of PR-10-like proteins in Medicago truncatula results in an antagonistic induction of other PR proteins and in an increased tolerance upon infection with the oomycete Aphanomyces euteiches. Planta 226, 5771.
  • 22
    Wen J, Vanek-Krebitz M, Hoffmann-Sommergruber K, Scheiner O & Breiteneder H (1997) The potential of Betv1 homologues, a nuclear multigene family, as phylogenetic markers in flowering plants. Mol Phylogenet Evol 8, 317333.
  • 23
    Somssich IE, Schmelzer E, Kawalleck P & Hahlbrock K (1988) Gene structure and in situ transcript localization of pathogenesis-related protein 1 in parsley. Mol Gen Genet 213, 9398.
  • 24
    Chadha P & Das RH (2006) A pathogenesis related protein, AhPR10 from peanut: an insight of its mode of antifungal activity. Planta 225, 213222.
  • 25
    Grote M (1999) In situ localization of pollen allergens by immunogold electron microscopy: allergens at unexpected sites. Int Arch Allergy Immunol 118, 16.
  • 26
    Ekramoddoullah AKM (2004) Physiology and molecular biology of a family of pathogenesis-related PR-10 proteins in conifers. J Crop Improve 10, 261280.
  • 27
    Balsamo RA, Wang J-L, Eckard KJ, Wang C-S & Lord EM (1995) Immunogold localization of a developmentally regulated, tapetal-specific, 15 kDa lily anther protein. Protoplasma 189, 1725.
  • 28
    Zhang RP, Wang YC, Liu GF & Li HY (2010) Cloning and characterization of a pathogenesis-related gene (Thpr10) from Tamarix Hispida. Acta Biol Cracov Bot 52, 1725.
  • 29
    Lee OR, Kim YJ, Balusamy SR, Khorolragchaa A, Sathiyaraj G, Kim MK & Yang DC (2012) Expression of the ginseng PgPR10-1 in Arabidopsis confers resistance against fungal and bacterial infection. Gene 506, 8592.
  • 30
    Mogensen JE, Wimmer R, Larsen JN, Spangfort MD & Otzen DE (2002) The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. J Biol Chem 277, 2368423692.
  • 31
    Somssich IE, Schmelzer E, Bollmann J & Hahlbrock K (1986) Rapid activation by fungal elicitor of genes encoding ‘pathogenesis-related’ proteins in cultured parsley cells. Proc Natl Acad Sci USA 83, 24272430.
  • 32
    Walter MH, Liu JW, Grand C, Lamb CJ & Hess D (1990) Bean pathogenesis-related (PR) proteins deduced from elicitor-induced transcripts are members of a ubiquitous new class of conserved PR proteins including pollen allergens. Mol Gen Genet 222, 353360.
  • 33
    Warner SA, Scott R & Draper J (1992) Characterisation of a wound-induced transcript from the monocot asparagus that shares similarity with a class of intracellular pathogenesis-related (PR) proteins. Plant Mol Biol 19, 555561.
  • 34
    Breiteneder H, Pettenburger K, Bito A, Valenta R, Kraft D, Rumpold H, Scheiner O & Breitenbach M (1989) The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene. EMBO J 8, 19351938.
  • 35
    Pinto MP & Ricardo CP (1995) Lupinus albus L. pathogenesis-related proteins that show similarity to PR-10 proteins. Plant Physiol 109, 13451351.
  • 36
    Puhringer H, Moll D, Hoffmann-Sommergruber K, Watillon B, Katinger H & Machado MLD (2000) The promoter of an apple Ypr10 gene, encoding the major allergen Mal d 1, is stress- and pathogen-inducible. Plant Sci 152, 3550.
  • 37
    Park CJ, Kim KJ, Shin R, Park JM, Shin YC & Paek KH (2004) Pathogenesis-related protein 10 isolated from hot pepper functions as a ribonuclease in an antiviral pathway. Plant J 37, 186198.
  • 38
    Xu P, Blancaflor EB & Roossinck MJ (2003) In spite of induced multiple defense responses, tomato plants infected with Cucumber mosaic virus and D satellite RNA succumb to systemic necrosis. Mol Plant Microbe Interact 16, 467476.
  • 39
    Fristensky B, Horovitz D & Hadwiger LA (1988) cDNA sequences for pea disease resistance response genes. Plant Mol Biol 11, 713715.
  • 40
    Esnault R, Buffard D, Breda C, Sallaud C, el Turk J & Kondorosi A (1993) Pathological and molecular characterizations of alfalfa interactions with compatible and incompatible bacteria, Xanthomonas campestris pv. alfalfae and Pseudomonas syringae pv. pisi. Mol Plant Microbe Interact 6, 655664.
  • 41
    Robert N, Ferran J, Breda C, Coutos-Thevenot P, Boulay M, Buffard D & Esnault R (2001) Molecular characterization of the incompatible interaction of vitis vinifera leaves with Pseudomonas syringae pv. pisi: expression of genes coding for stilbene synthase and class 10 PR protein. Eur J Plant Pathol 107, 249261.
  • 42
    Swoboda I, Scheiner O, Heberlebors E & Vicente O (1995) cDNA cloning and characterization of 3 genes in the Bet-V-1 gene family that encode pathogenesis-related proteins. Plant, Cell Environ 18, 865874.
  • 43
    Liu JJ, Ekramoddoullah AK, Piggott N & Zamani A (2005) Molecular cloning of a pathogen/wound-inducible PR10 promoter from Pinus monticola and characterization in transgenic Arabidopsis plants. Planta 221, 159169.
  • 44
    Swoboda I, Scheiner O, Kraft D, Breitenbach M, Heberle-Bors E & Vicente O (1994) A birch gene family encoding pollen allergens and pathogenesis-related proteins. Biochim Biophys Acta 1219, 457464.
  • 45
    Borsics T & Lados M (2002) Dodder infection induces the expression of a pathogenesis-related gene of the family PR-10 in alfalfa. J Exp Bot 53, 18311832.
  • 46
    Bahramnejad B, Goodwin PH, Zhang J, Atnaseo C & Erickson LR (2010) A comparison of two class 10 pathogenesis-related genes from alfalfa and their activation by multiple stresses and stress-related signaling molecules. Plant Cell Rep 29, 12351250.
  • 47
    Matton DP & Brisson N (1989) Cloning, expression, and sequence conservation of pathogenesis-related gene transcripts of potato. Mol Plant Microbe Interact 2, 325331.
  • 48
    Schmelzer E, Kruger-Lebus S & Hahlbrock K (1989) Temporal and spatial patterns of gene expression around sites of attempted fungal infection in parsley leaves. Plant Cell 1, 9931001.
  • 49
    Chiang CC & Hadwiger LA (1990) Cloning and characterization of a disease resistance response gene in pea inducible by Fusarium solani. Mol Plant Microbe Interact 3, 7885.
  • 50
    Jwa NS, Kumar Agrawal G, Rakwal R, Park CH & Prasad Agrawal V (2001) Molecular cloning and characterization of a novel Jasmonate inducible pathogenesis-related class 10 protein gene, JIOsPR10, from rice (Oryza sativa L.) seedling leaves. Biochem Biophys Res Commun 286, 973983.
  • 51
    Liu JJ, Ekramoddoullah AKM & Yu XS (2003) Differential expression of multiple PR10 proteins in western white pine following wounding, fungal infection and cold-hardening. Physiol Plant 119, 544553.
  • 52
    McGee JD, Hamer JE & Hodges TK (2001) Characterization of a PR-10 pathogenesis-related gene family induced in rice during infection with Magnaporthe grisea. Mol Plant Microbe Interact 14, 877886.
  • 53
    Midoh N & Iwata M (1996) Cloning and characterization of a probenazole-inducible gene for an intracellular pathogenesis-related protein in rice. Plant Cell Physiol 37, 918.
  • 54
    Lo SC, Hipskind JD & Nicholson RL (1999) cDNA cloning of a sorghum pathogenesis-related protein (PR-10) and differential expression of defense-related genes following inoculation with Cochliobolus heterostrophus or Colletotrichum sublineolum. Mol Plant Microbe Interact 12, 479489.
  • 55
    Ekramoddoullah AKM, Davidson JJ & Taylor DW (1998) A protein associated with frost hardiness of western white pine is up-regulated by infection in the white pine blister rust pathosystem. Can J Forest Res 28, 412417.
  • 56
    Katile SO, Perumal R, Rooney WL, Prom LK & Magill CW (2010) Expression of pathogenesis-related protein PR-10 in sorghum floral tissues in response to inoculation with Fusarium thapsinum and Curvularia lunata. Mol Plant Pathol 11, 93103.
  • 57
    Gomez-Gomez L, Rubio-Moraga A & Ahrazem O (2011) Molecular cloning and characterisation of a pathogenesis-related protein CsPR10 from Crocus sativus. Plant Biol (Stuttg) 13, 297303.
  • 58
    Agarwal P, Bhatt V, Singh R, Das M, Sopory SK & Chikara J (2012) Pathogenesis-related gene, JcPR-10a from Jatropha curcas exhibit RNase and antifungal activity. Mol Biotechnol in press, doi:10.1007/s12033-012-9579-7.
  • 59
    Ekramoddoullah AKM, Taylor D & Hawkins BJ (1995) Characterization of a fall protein of sugar pine and detection of its homolog associated with frost hardiness of western white-pine needles. Can J Forest Res 25, 11371147.
  • 60
    Lee OR, Pulla RK, Kim YJ, Balusamy SR & Yang DC (2011) Expression and stress tolerance of PR10 genes from Panax ginseng C. A. Meyer. Mol Biol Reports 39, 23652374.
  • 61
    Moons A, Prinsen E, Bauw G & Van Montagu M (1997) Antagonistic effects of abscisic acid and jasmonates on salt stress-inducible transcripts in rice roots. Plant Cell 9, 22432259.
  • 62
    Jain S, Srivastava S, Sarin NB & Kav NN (2006) Proteomics reveals elevated levels of PR 10 proteins in saline-tolerant peanut (Arachis hypogaea) calli. Plant Physiol Biochem 44, 253259.
  • 63
    Hashimoto M, Kisseleva L, Sawa S, Furukawa T, Komatsu S & Koshiba T (2004) A novel rice PR10 protein, RSOsPR10, specifically induced in roots by biotic and abiotic stresses, possibly via the jasmonic acid signaling pathway. Plant Cell Physiol 45, 550559.
  • 64
    El-Banna A, Hajirezaei MR, Wissing J, Ali Z, Vaas L, Heine-Dobbernack E, Jacobsen HJ, Schumacher HM & Kiesecker H (2010) Over-expression of PR-10a leads to increased salt and osmotic tolerance in potato cell cultures. J Biotechnol 150, 277287.
  • 65
    Dubos C & Plomion C (2001) Drought differentially affects expression of a PR-10 protein, in needles of maritime pine (Pinus pinaster Ait.) seedlings. J Exp Bot 52, 11431144.
  • 66
    Koistinen KM, Hassinen VH, Gynther PAM, Lehesranta SJ, Keinanen SI, Kokko HI, Oksanen EJ, Tervahauta AI, Auriola S & Karenlampi SO (2002) Birch PR-10c is induced by factors causing oxidative stress but appears not to confer tolerance to these agents. New Phytol 155, 381391.
  • 67
    Utriainen M, Kokko H, Auriola S, Sarrazin O & Karenlampi S (1998) PR-10 protein is induced by copper stress in roots and leaves of a Cu/Zn tolerant clone of birch, Betula pendula. Plant, Cell Environ 21, 821828.
  • 68
    Rakwal R, Agrawal GK & Yonekura M (1999) Separation of proteins from stressed rice (Oryza sativa L.) leaf tissues by two-dimensional polyacrylamide gel electrophoresis: induction of pathogenesis-related and cellular protectant proteins by jasmonic acid. UV irradiation and copper chloride. Electrophoresis 20, 34723478.
  • 69
    Handschuh L, Femiak I, Kasperska A, Figlerowicz M & Sikorski MM (2007) Structural and functional characteristics of two novel members of pathogensis-related multigene family of class 10 from yellow lupine+. Acta Biochim Pol 54, 783796.
  • 70
    Carpin S, Laffer S, Schoentgen F, Valenta R, Chenieux JC, Rideau M & Hamdi S (1998) Molecular characterization of a cytokinin-inducible periwinkle protein showing sequence homology with pathogenesis-related proteins and the Bet v 1 allergen family. Plant Mol Biol 36, 791798.
  • 71
    Rakwal R, Agrawal GK & Yonekura M (2001) Light-dependent induction of OsPR10 in rice (Oryza sativa L.) seedlings by the global stress signaling molecule jasmonic acid and protein phosphatase 2A inhibitors. Plant Sci 161, 469479.
  • 72
    Iturriaga EA, Leech MJ, Barratt DH & Wang TL (1994) Two ABA-responsive proteins from pea (Pisum sativum L.) are closely related to intracellular pathogenesis-related proteins. Plant Mol Biol 24, 235240.
  • 73
    Wang CS, Huang JC & Hu JH (1999) Characterization of two subclasses of PR-10 transcripts in lily anthers and induction of their genes through separate signal transduction pathways. Plant Mol Biol 40, 807814.
  • 74
    Walter MH, Liu JW, Wunn J & Hess D (1996) Bean ribonuclease-like pathogenesis-related protein genes (Ypr10) display complex patterns of developmental, dark-induced and exogenous-stimulus-dependent expression. Eur J Biochem 239, 281293.
  • 75
    Warner SA, Gill A & Draper J (1994) The developmental expression of the asparagus intracellular PR protein (AoPR1) gene correlates with sites of phenylpropanoid biosynthesis. Plant J 6, 3143.
  • 76
    Poupard P, Brunel N, Leduc N, Viemont JD, Strullu DG & Simoneau P (2001) Expression of a Bet v 1 homologue gene encoding a PR 10 protein in birch roots: induction by auxin and localization of the transcripts by in situ hybridization. Aust J Plant Physiol 28, 5763.
  • 77
    Lebel S, Schellenbaum P, Walter B & Maillot P (2010) Characterisation of the Vitis vinifera PR10 multigene family. BMC Plant Biol 10, 184.
  • 78
    Broderick K, Pittock C, Arioli T, Creaser EH, Weinman JJ & Rolfe BG (1997) Pathogenesis-related proteins in Trifolium subterraneum: a general survey and subsequent characterisation of a protein inducible by ethephon and redlegged earth mite attack. Aust J Plant Physiol 24, 819829.
  • 79
    Poupard P, Strullu DG & Simoneau P (1998) Two members of the Bet v 1 gene family encoding birch pathogenesis-related proteins display different patterns of root expression and wound-inducibility. Aust J Plant Physiol 25, 459464.
  • 80
    Warner SA, Scott R & Draper J (1993) Isolation of an asparagus intracellular PR gene (AoPR1) wound-responsive promoter by the inverse polymerase chain reaction and its characterization in transgenic tobacco. Plant J 3, 191201.
  • 81
    Mylona P, Moerman M, Yang WC, Gloudemans T, Van de Kerckhove J, van Kammen A, Bisseling T & Franssen HJ (1994) The root epidermis-specific pea gene RH2 is homologous to a pathogenesis-related gene. Plant Mol Biol 26, 3950.
  • 82
    Yamamoto M, Torikai S & Oeda K (1997) A major root protein of carrots with high homology to intracellular pathogenesis-related (PR) proteins and pollen allergens. Plant Cell Physiol 38, 10801086.
  • 83
    Constabel CP & Brisson N (1995) Stigma-specific and vascular-specific expression of the Pr-10a gene of potato – a novel pattern of expression of a pathogenesis-related gene. Mol Plant Microbe Interact 8, 104113.
  • 84
    Atkinsona RG, Perrya J, Matsuib T, Rossa GS & Macrae EA (1996) A stress-, pathogenesis-, and allergen-related cDNA in apple fruit is also ripening-related. NZ J Crop Horticult Sci 24, 103107.
  • 85
    Larsen JN, Stroman P & Ipsen H (1992) PCR based cloning and sequencing of isogenes encoding the tree pollen major allergen Car b I from Carpinus betulus, hornbeam. Mol Immunol 29, 703711.
  • 86
    Apold J, Florvaag E & Elsayed S (1981) Comparative studies on tree-pollen allergens. 1. Isolation and partial characterization of a major allergen from birch pollen (Betula-Verrucosa). Int Arch Allergy Immunol 64, 439447.
  • 87
    Barratt DHP & Clark JA (1991) Proteins arising during the late stages of embryogenesis in Pisum-Sativum L. Planta 184, 1423.
  • 88
    Wu F, Yan M, Li Y, Chang S, Song X, Zhou Z & Gong W (2003) cDNA cloning, expression, and mutagenesis of a PR-10 protein SPE-16 from the seeds of Pachyrrhizus erosus. Biochem Biophys Res Commun 312, 761766.
  • 89
    Strauss JF III, Kishida T, Christenson LK, Fujimoto T & Hiroi H (2003) START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells. Mol Cell Endocrinol 202, 5965.
  • 90
    Radauer C, Lackner P & Breiteneder H (2008) The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands. BMC Evol Biol 8, 286.
  • 91
    Liu JJ & Ekramoddoullah AKM (2006) The family 10 of plant pathogenesis-related proteins: their structure, regulation, and function in response to biotic and abiotic stresses. Physiol Mol Plant P 68, 313.
  • 92
    Ilari A, Franceschini S, Bonamore A, Arenghi F, Botta B, Macone A, Pasquo A, Bellucci L & Boffi A (2009) Structural basis of enzymatic (S)-norcoclaurine biosynthesis. J Biol Chem 284, 897904.
  • 93
    Lytle BL, Song J, de la Cruz NB, Peterson FC, Johnson KA, Bingman CA, Phillips GN Jr & Volkman BF (2009) Structures of two Arabidopsis thaliana major latex proteins represent novel helix-grip folds. Proteins 76, 237243.
  • 94
    Michalska K, Fernandes H, Sikorski M & Jaskolski M (2010) Crystal structure of Hyp-1, a St. John's wort protein implicated in the biosynthesis of hypericin. J Struct Biol 169, 161171.
  • 95
    Breiteneder H, Hoffmann-Sommergruber K, O'Riordain G, Susani M, Ahorn H, Ebner C, Kraft D & Scheiner O (1995) Molecular characterization of Api g 1, the major allergen of celery (Apium graveolens), and its immunological and structural relationships to a group of 17-kDa tree pollen allergens. Eur J Biochem 233, 484489.
  • 96
    Vanek-Krebitz M, Hoffmann-Sommergruber K, da Camara L, Machado M, Susani M, Ebner C, Kraft D, Scheiner O & Breiteneder H (1995) Cloning and sequencing of Mal d 1, the major allergen from apple (Malus domestica), and its immunological relationship to Bet v 1, the major birch pollen allergen. Biochem Biophys Res Commun 214, 538551.
  • 97
    Nessler CL, Kurz WG & Pelcher LE (1990) Isolation and analysis of the major latex protein genes of opium poppy. Plant Mol Biol 15, 951953.
  • 98
    Osmark P, Boyle B & Brisson N (1998) Sequential and structural homology between intracellular pathogenesis-related proteins and a group of latex proteins. Plant Mol Biol 38, 12431246.
  • 99
    Pozueta-Romero J, Klein M, Houlne G, Schantz ML, Meyer B & Schantz R (1995) Characterization of a family of genes encoding a fruit-specific wound-stimulated protein of bell pepper (Capsicum annuum): identification of a new family of transposable elements. Plant Mol Biol 28, 10111025.
  • 100
    Aggelis A, John I, Karvouni Z & Grierson D (1997) Characterization of two cDNA clones for mRNAs expressed during ripening of melon (Cucumis melo L.) fruits. Plant Mol Biol 33, 313322.
  • 101
    Jones CS, Davies HV, McNicol RJ & Taylor MA (1998) Cloning of three genes up-regulated in ripening raspberry fruit (Rubus idaeus cv. Glen clova). J Plant Physiol 153, 643648.
  • 102
    Stromvik MV, Sundararaman VP & Vodkin LO (1999) A novel promoter from soybean that is active in a complex developmental pattern with and without its proximal 650 base pairs. Plant Mol Biol 41, 217231.
  • 103
    Nam YW, Tichit L, Leperlier M, Cuerq B, Marty I & Lelievre JM (1999) Isolation and characterization of mRNAs differentially expressed during ripening of wild strawberry (Fragaria vesca L.) fruits. Plant Mol Biol 39, 629636.
  • 104
    Suyama T, Yamada K, Mori H, Takeno K & Yamaki S (1999) Cloning cDNAs for genes preferentially expressed during fruit growth in cucumber. J Am Soc Hortic Sci 124, 136139.
  • 105
    Kloos DU, Oltmanns H, Dock C, Stahl D & Hehl R (2002) Isolation and molecular analysis of six taproot expressed genes from sugar beet. J Exp Bot 53, 15331534.
  • 106
    Wu FZ, Lu TC, Shen Z, Wang BC & Wang HX (2008) N-terminal acetylation of two major latex proteins from Arabidopsis thaliana using electrospray ionization tandem mass spectrometry. Plant Mol Biol Rep 26, 8897.
  • 107
    Ruperti B, Bonghi C, Ziliotto F, Pagni S, Rasori A, Varotto S, Tonutti P, Giovannoni JJ & Ramina A (2002) Characterization of a major latex protein (MLP) gene down-regulated by ethylene during peach fruitlet abscission. Plant Sci 163, 265272.
  • 108
    Sun H, Kim MK, Pulla RK, Kim YJ & Yang DC (2009) Isolation and expression analysis of a novel major latex-like protein (MLP151) gene from Panax ginseng. Mol Biol Rep 37, 22152222.
  • 109
    Pasternak O, Bujacz GD, Fujimoto Y, Hashimoto Y, Jelen F, Otlewski J, Sikorski MM & Jaskolski M (2006) Crystal structure of Vigna radiata cytokinin-specific binding protein in complex with zeatin. Plant Cell 18, 26222634.
  • 110
    Fernandes H, Pasternak O, Bujacz G, Bujacz A, Sikorski MM & Jaskolski M (2008) Lupinus luteus pathogenesis-related protein as a reservoir for cytokinin. J Mol Biol 378, 10401051.
  • 111
    Fernandes H, Bujacz A, Bujacz G, Jelen F, Jasinski M, Kachlicki P, Otlewski J, Sikorski MM & Jaskolski M (2009) Cytokinin-induced structural adaptability of a Lupinus luteus PR-10 protein. FEBS J 276, 15961609.
  • 112
    Kofler S, Asam C, Eckhard U, Wallner M, Ferreira F & Brandstetter H (2012) Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen bet v 1. J Mol Biol 422, 109123.
  • 113
    Sheard LB & Zheng N (2009) Plant biology: signal advance for abscisic acid. Nature 462, 575576.
  • 114
    Sussman MR & Phillips GN Jr (2009) Plant science. How plant cells go to sleep for a long, long time. Science 326, 13561357.
  • 115
    Hedden P (2008) Plant biology: gibberellins close the lid. Nature 456, 455456.
  • 116
    Murase K, Hirano Y, Sun TP & Hakoshima T (2008) Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. Nature 456, 459463.
  • 117
    Shimada A, Ueguchi-Tanaka M, Nakatsu T, Nakajima M, Naoe Y, Ohmiya H, Kato H & Matsuoka M (2008) Structural basis for gibberellin recognition by its receptor GID1. Nature 456, 520523.
  • 118
    Santner A & Estelle M (2009) Recent advances and emerging trends in plant hormone signalling. Nature 459, 10711078.
  • 119
    Samanani N, Liscombe DK & Facchini PJ (2004) Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis. Plant J 40, 302313.
  • 120
    Bais HP, Vepachedu R, Lawrence CB, Stermitz FR & Vivanco JM (2003) Molecular and biochemical characterization of an enzyme responsible for the formation of hypericin in St. John's wort (Hypericum perforatum L.). J Biol Chem 278, 3241332422.
  • 121
    Luk LY, Bunn S, Liscombe DK, Facchini PJ & Tanner ME (2007) Mechanistic studies on norcoclaurine synthase of benzylisoquinoline alkaloid biosynthesis: an enzymatic Pictet–Spengler reaction. Biochemistry 46, 1015310161.
  • 122
    Lee EJ & Facchini P (2010) Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family. Plant Cell 22, 34893503.
  • 123
    Kosuth J, Katkovcinova Z, Olexova P & Cellarova E (2007) Expression of the hyp-1 gene in early stages of development of Hypericum perforatum L. Plant Cell Rep 26, 211217.
  • 124
    Kusari S, Zuhlke S, Kosuth J, Cellarova E & Spiteller M (2009) Light-independent metabolomics of endophytic Thielavia subthermophila provides insight into microbial hypericin biosynthesis. J Nat Prod 72, 18251835.
  • 125
    Hoffmann-Sommergruber K, Vanek-Krebitz M, Radauer C, Wen J, Ferreira F, Scheiner O & Breiteneder H (1997) Genomic characterization of members of the Bet v 1 family: genes coding for allergens and pathogenesis-related proteins share intron positions. Gene 197, 91100.
  • 126
    Gonneau M, Pagant S, Brun F & Laloue M (2001) Photoaffinity labelling with the cytokinin agonist azido-CPPU of a 34 kDa peptide of the intracellular pathogenesis-related protein family in the moss Physcomitrella patens. Plant Mol Biol 46, 539548.
  • 127
    Facchini PJ & St-Pierre B (2005) Synthesis and trafficking of alkaloid biosynthetic enzymes. Curr Opin Plant Biol 8, 657666.
  • 128
    Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN & Bourne PE (2000) The Protein Data Bank. Nucleic Acids Res 28, 235242.
  • 129
    Biesiadka J, Bujacz G, Sikorski MM & Jaskolski M (2002) Crystal structures of two homologous pathogenesis-related proteins from yellow lupine. J Mol Biol 319, 12231234.
  • 130
    Berkner H, Neudecker P, Mittag D, Ballmer-Weber BK, Schweimer K, Vieths S & Rosch P (2009) Cross-reactivity of pollen and food allergens: soybean Gly m 4 is a member of the Bet v 1 superfamily and closely resembles yellow lupine proteins. Biosci Rep 29, 183192.
  • 131
    Saraste M, Sibbald PR & Wittinghofer A (1990) The P-loop – a common motif in ATP- and GTP-binding proteins. Trends Biochem Sci 15, 430434.
  • 132
    Koistinen KM, Soininen P, Venalainen TA, Hayrinen J, Laatikainen R, Perakyla M, Tervahauta AI & Karenlampi SO (2005) Birch PR-10c interacts with several biologically important ligands. Phytochemistry 66, 25242533.
  • 133
    Mattila K & Renkonen R (2009) Modelling of Bet v 1 binding to lipids. Scand J Immunol 70, 116124.
  • 134
    Muller P, Kopke S & Sheldrick GM (2003) Is the bond-valence method able to identify metal atoms in protein structures? Acta Crystallogr D Biol Crystallogr 59, 3237.
  • 135
    Brese NE & O'Keeffe M (1991) Bond-valence parameters for solids. Acta Crystallogr B 47, 192197.
  • 136
    Krissinel E & Henrick K (2004) Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D Biol Crystallogr 60, 22562268.
  • 137
    Laskowski RA (1995) SURFNET: a program for visualizing molecular surfaces, cavities, and intermolecular interactions. J Mol Graph 13, 323330, 307–328.
  • 138
    Gajhede M, Osmark P, Poulsen FM, Ipsen H, Larsen JN, Joost van Neerven RJ, Schou C, Lowenstein H & Spangfort MD (1996) X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy. Nat Struct Biol 3, 10401045.
  • 139
    Pasternak O, Biesiadka J, Dolot R, Handschuh L, Bujacz G, Sikorski MM & Jaskolski M (2005) Structure of a yellow lupin pathogenesis-related PR-10 protein belonging to a novel subclass. Acta Crystallogr D Biol Crystallogr 61, 99107.
  • 140
    Kabsch W (1976) Solution for best rotation to relate 2 sets of vectors. Acta Crystallogr A 32, 922923.
  • 141
    Pasternak O, Bujacz A, Biesiadka J, Bujacz G, Sikorski M & Jaskolski M (2008) MAD phasing using the (Ta6Br12)2+ cluster: a retrospective study. Acta Crystallogr D Biol Crystallogr 64, 595606.
  • 142
    Holm L & Rosenstrom P (2010) Dali server: conservation mapping in 3D. Nucleic Acids Res 38, W545W549.
  • 143
    Kallen CB, Billheimer JT, Summers SA, Stayrook SE, Lewis M & Strauss JF III (1998) Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein. J Biol Chem 273, 2628526288.
  • 144
    Miller WL (2007) StAR search – what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import. Mol Endocrinol 21, 589601.
  • 145
    Stocco DM & Clark BJ (1996) Role of the steroidogenic acute regulatory protein (StAR) in steroidogenesis. Biochem Pharmacol 51, 197205.
  • 146
    Clark BJ, Wells J, King SR & Stocco DM (1994) The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem 269, 2831428322.
  • 147
    Alpy F & Tomasetto C (2005) Give lipids a START: the StAR-related lipid transfer (START) domain in mammals. J Cell Sci 118, 27912801.
  • 148
    Tsujishita Y & Hurley JH (2000) Structure and lipid transport mechanism of a StAR-related domain. Nat Struct Biol 7, 408414.
  • 149
    Romanowski MJ, Soccio RE, Breslow JL & Burley SK (2002) Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain. Proc Natl Acad Sci USA 99, 69496954.
  • 150
    Roderick SL, Chan WW, Agate DS, Olsen LR, Vetting MW, Rajashankar KR & Cohen DE (2002) Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat Struct Biol 9, 507511.
  • 151
    Pennisi E (2009) Plant biology. Stressed out over a stress hormone. Science 324, 10121013.
  • 152
    Klingler JP, Batelli G & Zhu JK (2010) ABA receptors: the START of a new paradigm in phytohormone signalling. J Exp Bot 61, 31993210.
  • 153
    Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V et al. (2009) A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature 462, 602608.
  • 154
    Ames BD, Korman TP, Zhang W, Smith P, Vu T, Tang Y & Tsai SC (2008) Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. Proc Natl Acad Sci USA 105, 53495354.
  • 155
    Bufe A, Spangfort MD, Kahlert H, Schlaak M & Becker WM (1996) The major birch pollen allergen, Bet v 1, shows ribonuclease activity. Planta 199, 413415.
  • 156
    Faber C, Lindemann A, Sticht H, Ejchart A, Kungl A, Susani M, Frank RW, Kraft D, Breitenbach M & Rosch P (1996) Secondary structure and tertiary fold of the birch pollen allergen Bet v 1 in solution. J Biol Chem 271, 1924319250.
  • 157
    Koistinen KM, Kokko HI, Hassinen VH, Tervahauta AI, Auriola S & Karenlampi SO (2002) Stress-related RNase PR-10c is post-translationally modified by glutathione in birch. Plant, Cell Environ 25, 707715.
  • 158
    Wu F, Li Y, Chang S, Zhou Z, Wang F, Song X, Lin Y & Gong W (2002) Purification, characterization and preliminary crystallographic studies of a PR-10 protein from Pachyrrhizus erosus seeds. Acta Crystallogr D Biol Crystallogr 58, 21652167.
  • 159
    Scholl I, Kalkura N, Shedziankova Y, Bergmann A, Verdino P, Knittelfelder R, Kopp T, Hantusch B, Betzel C, Dierks K et al. (2005) Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice. J Immunol 175, 66456650.
  • 160
    Ma Y, Gadermaier G, Bohle B, Bolhaar S, Knulst A, Markovic-Housley Z, Breiteneder H, Briza P, Hoffmann-Sommergruber K & Ferreira F (2006) Mutational analysis of amino acid positions crucial for IgE-binding epitopes of the major apple (Malus domestica) allergen, Mal d 1. Int Arch Allergy Immunol 139, 5362.
  • 161
    Yan Q, Qi X, Jiang Z, Yang S & Han L (2008) Characterization of a pathogenesis-related class 10 protein (PR-10) from Astragalus mongholicus with ribonuclease activity. Plant Physiol Biochem 46, 9399.
  • 162
    Zawadzki P, Slosarek G, Boryski J & Wojtaszek P (2010) A fluorescence correlation spectroscopy study of ligand interaction with cytokinin-specific binding protein from mung bean. Biol Chem 391, 4353.
  • 163
    Samanani N & Facchini PJ (2002) Purification and characterization of norcoclaurine synthase. The first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants. J Biol Chem 277, 3387833883.
  • 164
    Moiseyev GP, Beintema JJ, Fedoreyeva LI & Yakovlev GI (1994) High sequence similarity between a ribonuclease from ginseng calluses and fungus-elicited proteins from parsley indicates that intracellular pathogenesis-related proteins are ribonucleases. Planta 193, 470472.
  • 165
    Swoboda I, Hoffmann Sommergruber K, O'Riordain G, Scheiner O, Heberle Bors E & Vicente O (1996) Bet v 1 proteins, the major birch pollen allergens and members of a family of conserved pathogenesis-related proteins, show ribonuclease activity in vitro. Physiol Plant 96, 433438.
  • 166
    Bantignies B, Seguin J, Muzac I, Dedaldechamp F, Gulick P & Ibrahim R (2000) Direct evidence for ribonucleolytic activity of a PR-10-like protein from white lupin roots. Plant Mol Biol 42, 871881.
  • 167
    Zhou XJ, Lu S, Xu YH, Wang JW & Chen XY (2002) A cotton cDNA (GaPR-10) encoding a pathogenesis-related 10 protein with in vitro ribonuclease activity. Plant Sci 162, 629636.
  • 168
    Liu X, Huang B, Lin J, Fei J, Chen Z, Pang Y, Sun X & Tang K (2006) A novel pathogenesis-related protein (SsPR10) from Solanum surattense with ribonucleolytic and antimicrobial activity is stress- and pathogen-inducible. J Plant Physiol 163, 546556.
  • 169
    Srivastava S, Emery RJN, Kurepin LV, Reid DM, Fristensky B & Kav NNV (2006) Pea PR 10.1 is a ribonuclease and its transgenic expression elevates cytokinin levels. Plant Growth Regul 49, 1725.
  • 170
    Srivastava S, Emery RJN, Rahman MH & Kav NNV (2007) A crucial role for cytokinins in pea ABR17-mediated enhanced germination and early seedling growth of Arabidopsis thaliana under saline and low-temperature stresses. J Plant Growth Regul 26, 2637.
  • 171
    Krishnaswamy S, Baral PK, James MN & Kav NN (2011) Site-directed mutagenesis of histidine 69 and glutamic acid 148 alters the ribonuclease activity of pea ABR17 (PR10.4). Plant Physiol Biochem 49, 958962.
  • 172
    Zubini P, Zambelli B, Musiani F, Ciurli S, Bertolini P & Baraldi E (2009) The RNA hydrolysis and the cytokinin binding activities of PR-10 proteins are differently performed by two isoforms of the Pru p 1 peach major allergen and are possibly functionally related. Plant Physiol 150, 12351247.
  • 173
    Pungartnik C, da Silva AC, de Melo SA, Gramacho KP, de Mattos Cascardo JC, Brendel M, Micheli F & da Silva Gesteira A (2009) High-affinity copper transport and Snq2 export permease of Saccharomyces cerevisiae modulate cytotoxicity of PR-10 from Theobroma cacao. Mol Plant Microbe Interact 22, 3951.
  • 174
    Chen ZY, Brown RL, Rajasekaran K, Damann KE & Cleveland TE (2006) Identification of a maize kernel pathogenesis-related protein and evidence for its involvement in resistance to Aspergillus flavus infection and aflatoxin production. Phytopathology 96, 8795.
  • 175
    Xie YR, Chen ZY, Brown RL & Bhatnagar D (2010) Expression and functional characterization of two pathogenesis-related protein 10 genes from Zea mays. J Plant Physiol 167, 121130.
  • 176
    Choi DS, Hwang IS & Hwang BK (2012) Requirement of the cytosolic interaction between PATHOGENESIS-RELATED PROTEIN10 and LEUCINE-RICH REPEAT PROTEIN1 for cell death and defense signaling in pepper. Plant Cell 24, 16751690.
  • 177
    Fernandes H, Konieczna M, Kolodziejczyk R, Bujacz G, Sikorski M & Jaskolski M (2008) Crystallization and preliminary crystallographic studies of Hyp-1, a St John's wort protein implicated in the biosynthesis of hypericin. Acta Crystallogr F Struct Biol Cryst Commun 64, 405408.
  • 178
    Kosuth J, Smelcerovic A, Borsch T, Zuehlke S, Karppinen K, Spiteller M, Hohtola A & Cellarova E (2011) The hyp-1 gene is not a limiting factor for hypericin biosynthesis in the genus Hypericum. Funct Plant Biol 38, 3543.
  • 179
    Kusari S, Lamshoft M, Zuhlke S & Spiteller M (2008) An endophytic fungus from Hypericum perforatum that produces hypericin. J Nat Prod 71, 159162.
  • 180
    Liscombe DK, MacLeod BP, Loukanina N, Nandi OI & Facchini PJ (2005) Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms. Phytochemistry 66, 25012520.
  • 181
    Minami H, Dubouzet E, Iwasa K & Sato F (2007) Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem 282, 62746282.
  • 182
    Andrade LB, Oliveira AS, Ribeiro JK, Kiyota S, Vasconcelos IM, de Oliveira JT & de Sales MP (2010) Effects of a novel pathogenesis-related class 10 (PR-10) protein from Crotalaria pallida Roots with papain inhibitory activity against root-knot nematode Meloidogyne incognita. J Agric Food Chem 58, 41454152.
  • 183
    Flores T, Alape-Giron A, Flores-Diaz M & Flores HE (2002) Ocatin. A novel tuber storage protein from the Andean tuber crop oca with antibacterial and antifungal activities. Plant Physiol 128, 12911302.
  • 184
    Wang KH, Sipes BS & Schmitt DP (2002) Crotalaria as a cover crop for nematode management: areview. Nematropica 32, 3557.
  • 185
    Ariizumi T & Toriyama K (2011) Genetic regulation of sporopollenin synthesis and pollen exine development. Annu Rev Plant Biol 62, 437460.
  • 186
    Huang JC, Chang FC & Wang CS (1997) Characterization of a lily tapetal transcript that shares sequence similarity with a class of intracellular pathogenesis-related (IPR) proteins. Plant Mol Biol 34, 681686.
  • 187
    Ukaji N, Kuwabara C, Takezawa D, Arakawa K & Fujikawa S (2004) Accumulation of pathogenesis-related (PR) 10/Bet v 1 protein homologues in mulberry (Morus bombycis Koidz.) tree during winter. Plant, Cell Environ 27, 11121121.
  • 188
    Goulas E, Richard-Molard C, Le Dily F, Le Dantec C, Ozouf J & Ourry A (2007) A cytosolic vegetative storage protein (TrVSP) from white clover is encoded by a cold-inducible gene. Physiol Plant 129, 567577.
  • 189
    Archambault A & Stromvik MV (2011) PR-10, defensin and cold dehydrin genes are among those over expressed in Oxytropis (Fabaceae) species adapted to the Arctic. Funct Integr Genomics 11, 497505.
  • 190
    Yu X, Ekramoddoullah AK & Misra S (2000) Characterization of Pin m III cDNA in western white pine. Tree Physiol 20, 663671.
  • 191
    Mogensen JE, Ipsen H, Holm J & Otzen DE (2004) Elimination of a misfolded folding intermediate by a single point mutation. Biochemistry 43, 33573367.
  • 192
    Renkonen J, Mattila P, Lehti S, Makinen J, Sormunen R, Tervo T, Paavonen T & Renkonen R (2009) Birch pollen allergen Bet v 1 binds to and is transported through conjunctival epithelium in allergic patients. Allergy 64, 868875.
  • 193
    Joenvaara S, Mattila P, Renkonen J, Makitie A, Toppila-Salmi S, Lehtonen M, Salmi P, Lehti S, Makinen J, Sormunen R et al. (2009) Caveolar transport through nasal epithelium of birch pollen allergen Bet v 1 in allergic patients. J Allergy Clin Immunol 124, 135142. e131–121.
  • 194
    Neudecker P, Schweimer K, Nerkamp J, Scheurer S, Vieths S, Sticht H & Rosch P (2001) Allergic cross-reactivity made visible: solution structure of the major cherry allergen Pru av 1. J Biol Chem 276, 2275622763.
  • 195
    Nagata R, Kawachi E, Hashimoto Y & Shudo K (1993) Cytokinin-specific binding protein in etiolated mung bean seedlings. Biochem Biophys Res Commun 191, 543549.
  • 196
    Clouse SD (1996) Molecular genetic studies confirm the role of brassinosteroids in plant growth and development. Plant J 10, 18.
  • 197
    Clouse S (2001) Brassinosteroids. Curr Biol 11, R904.
  • 198
    Markovic-Housley Z, Basle A, Padavattan S, Maderegger B, Schirmer T & Hoffmann-Sommergruber K (2009) Structure of the major carrot allergen Dau c 1. Acta Crystallogr D Biol Crystallogr 65, 12061212.
  • 199
    Breiteneder H & Ebner C (2000) Molecular and biochemical classification of plant-derived food allergens. J Allergy Clin Immunol 106, 2736.
  • 200
    Schenk MF, Cordewener JH, America AH, Van't Westende WP, Smulders MJ & Gilissen LJ (2009) Characterization of PR-10 genes from eight Betula species and detection of Bet v 1 isoforms in birch pollen. BMC Plant Biol 9, 24.
  • 201
    Vieths S, Scheurer S & Ballmer-Weber B (2002) Current understanding of cross-reactivity of food allergens and pollen. Ann N Y Acad Sci 964, 4768.
  • 202
    Ipsen H & Lowenstein H (1983) Isolation and immunochemical characterization of the major allergen of birch pollen (Betula verrucosa). J Allergy Clin Immunol 72, 150159.
  • 203
    Swoboda I, Jilek A, Ferreira F, Engel E, Hoffmann-Sommergruber K, Scheiner O, Kraft D, Breiteneder H, Pittenauer E, Schmid E et al. (1995) Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid chromatography, mass spectrometry, and cDNA cloning. J Biol Chem 270, 26072613.
  • 204
    Ferreira F, Hirtenlehner K, Jilek A, Godnik-Cvar J, Breiteneder H, Grimm R, Hoffmann-Sommergruber K, Scheiner O, Kraft D, Breitenbach M et al. (1996) Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy. J Exp Med 183, 599609.
  • 205
    Spangfort MD, Mirza O, Svensson LA, Larsen JN, Gajhede M & Ipsen H (1999) Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment. Acta Crystallogr D Biol Crystallogr 55, 20352036.
  • 206
    Mirza O, Henriksen A, Ipsen H, Larsen JN, Wissenbach M, Spangfort MD & Gajhede M (2000) Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J Immunol 165, 331338.
  • 207
    Spangfort MD, Mirza O, Ipsen H, Van Neerven RJ, Gajhede M & Larsen JN (2003) Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. J Immunol 171, 30843090.
  • 208
    Yeo D, Abe T, Abe H, Sakurai A, Takio K, Dohmae N, Takahashi N & Yoshida S (1996) Partial characterization of a 17 kDa acidic protein, EFP, induced by thiocarbamate in the early flowering phase in Asparagus seedlings. Plant Cell Physiol 37, 935940.
  • 209
    Eckey-Kaltenbach H, Kiefer E, Grosskopf E, Ernst D & Sandermann H Jr (1997) Differential transcript induction of parsley pathogenesis-related proteins and of a small heat shock protein by ozone and heat shock. Plant Mol Biol 33, 343350.
  • 210
    Neudecker P, Lehmann K, Nerkamp J, Haase T, Wangorsch A, Fotisch K, Hoffmann S, Rosch P, Vieths S & Scheurer S (2003) Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure. Biochem J 376, 97107.
  • 211
    Holm J, Gajhede M, Ferreras M, Henriksen A, Ipsen H, Larsen JN, Lund L, Jacobi H, Millner A, Wurtzen PA et al. (2004) Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses. J Immunol 173, 52585267.
  • 212
    Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F & Achatz G (2010) Antigen aggregation decides the fate of the allergic immune response. J Immunol 184, 725735.
  • 213
    Schirmer T, Hoffimann-Sommergrube K, Susani M, Breiteneder H & Markovic-Housley Z (2005) Crystal structure of the major celery allergen Api g 1: molecular analysis of cross-reactivity. J Mol Biol 351, 11011109.
  • 214
    Bollen MA, Wichers HJ, Helsper JPFG, Savelkoul HFJ & van Boekel MAJS (2010) Thermodynamic characterization of the PR-10 allergens Bet v 1, Api g 1 and Dau c 1 and pH-dependence of nApi g 1 and nDau c 1. Food Chem 119, 241248.
  • 215
    Gaier S, Marsh J, Oberhuber C, Rigby NM, Lovegrove A, Alessandri S, Briza P, Radauer C, Zuidmeer L, van Ree R et al. (2008) Purification and structural stability of the peach allergens Pru p 1 and Pru p 3. Mol Nutr Food Res 52, S220S229.
  • 216
    Berkner H, Schweimer K, Matecko I & Rosch P (2008) Conformation, catalytic site, and enzymatic mechanism of the PR10 allergen-related enzyme norcoclaurine synthase. Biochem J 413, 281290.
  • 217
    Gruber P, Vieths S, Wangorsch A, Nerkamp J & Hofmann T (2004) Maillard reaction and enzymatic browning affect the allergenicity of Pru av 1, the major allergen from cherry (Prunus avium). J Agric Food Chem 52, 40024007.
  • 218
    Laffer S, Hamdi S, Lupinek C, Sperr WR, Valent P, Verdino P, Keller W, Grote M, Hoffmann-Sommergruber K, Scheiner O et al. (2003) Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family. Biochem J 373, 261269.
  • 219
    Himly M, Nony E, Chabre H, Van Overtvelt L, Neubauer A, van Ree R, Buchheit KH, Vieths S, Moingeon P & Ferreira F (2009) Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v 1.0101 as biological reference preparation. Allergy 64, 10381045.
  • 220
    Sancho AI, Wangorsch A, Jensen BM, Watson A, Alexeev Y, Johnson PE, Mackie AR, Neubauer A, Reese G, Ballmer-Weber B et al. (2011) Responsiveness of the major birch allergen Bet v 1 scaffold to the gastric environment: impact on structure and allergenic activity. Mol Nutr Food Res 55, 16901699.
  • 221
    Mutschlechner S, Egger M, Briza P, Wallner M, Lackner P, Karle A, Vogt AB, Fischer GF, Bohle B & Ferreira F (2010) Naturally processed T cell-activating peptides of the major birch pollen allergen. J Allergy Clin Immunol 125, 711718, 718 e711–718 e712.
  • 222
    Schimek EM, Zwolfer B, Briza P, Jahn-Schmid B, Vogel L, Vieths S, Ebner C & Bohle B (2005) Gastrointestinal digestion of Bet v 1-homologous food allergens destroys their mediator-releasing, but not T cell-activating, capacity. J Allergy Clin Immunol 116, 13271333.
  • 223
    Luttkopf D, Muller U, Skov PS, Ballmer-Weber BK, Wuthrich B, Skamstrup Hansen K, Poulsen LK, Kastner M, Haustein D & Vieths S (2002) Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01. Mol Immunol 38, 515525.
  • 224
    Arakane F, King SR, Du Y, Kallen CB, Walsh LP, Watari H, Stocco DM & Strauss JF III (1997) Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity. J Biol Chem 272, 3265632662.
  • 225
    Hirel PH, Schmitter MJ, Dessen P, Fayat G & Blanquet S (1989) Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid. Proc Natl Acad Sci USA 86, 82478251.
  • 226
    Flinta C, Persson B, Jornvall H & von Heijne G (1986) Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem 154, 193196.
  • 227
    Schweimer K, Sticht H, Nerkamp J, Boehm M, Breitenbach M, Vieths S & Rosch P (1999) NMR spectroscopy reveals common structural features of the birch pollen allergen Bet v 1 and the cherry allergen Pru a 1. Appl Magn Reson 17, 449464.
  • 228
    Seutter von Loetzen C, Schweimer K, Schwab W, Rosch P & Hartl-Spiegelhauer O (2012) Solution structure of the strawberry allergen Fra a 1. Biosci Rep 32, 567575.
  • 229
    Chenna R, Sugawara H, Koike T, Lopez R, Gibson TJ, Higgins DG & Thompson JD (2003) Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res 31, 34973500.
  • 230
    Letunic I & Bork P (2011) Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy. Nucleic Acids Res 39, W475W478.