SEARCH

SEARCH BY CITATION

References

  • 1
    Lewartowski B (2000) Excitation–contraction coupling in cardiac muscle revisited. J Physiol Pharmacol 51, 371386.
  • 2
    Lamb GD (2000) Excitation–contraction coupling in skeletal muscle: comparisons with cardiac muscle. Clin Exp Pharmacol Physiol 27, 216224.
  • 3
    Beam KG & Bannister RA (2010) Looking for answers to EC coupling's persistent questions. J Gen Physiol 136, 712.
  • 4
    Franzini-Armstrong C (1970) Studies of the Triad: I. Structure of the junction in Frog Twitch fibers. J Cell Biol 47, 488499.
  • 5
    Campbell KP, Knudson CM, Imagawa T, Leung AT, Sutko JL, Kahl SD, Raab CR & Madson L (1987) Identification and characterization of the high affinity [3H]ryanodine receptor of the junctional sarcoplasmic reticulum Ca2 +  release channel. J Biol Chem 262, 64606463.
  • 6
    Inui M, Saito A & Fleischer S (1987) Purification of the ryanodine receptor and identity with feet structures of junctional terminal cisternae of sarcoplasmic reticulum from fast skeletal muscle. J Biol Chem 262, 17401747.
  • 7
    Lai FA, Erickson HP, Rousseau E, Liu QY & Meissner G (1988) Purification and reconstitution of the calcium release channel from skeletal muscle. Nature 331, 315319.
  • 8
    Rogers EF, Koniuszy FR, Shavel J Jr. & Folkers K (1948) Plant insecticides; ryanodine, a new alkaloid from Ryania speciosa Vahl. J Am Chem Soc 70, 30863088.
  • 9
    Mignery GA, Sudhof TC, Takei K & De Camilli P (1989) Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor. Nature 342, 192195.
  • 10
    Furuichi T, Yoshikawa S & Mikoshiba K (1989) Nucleotide sequence of cDNA encoding P400 protein in the mouse cerebellum. Nucleic Acids Res 17, 53855386.
  • 11
    Tu H, Wang Z & Bezprozvanny I (2005) Modulation of mammalian inositol 1,4,5-trisphosphate receptor isoforms by calcium: a role of calcium sensor region. Biophys J 88, 10561069.
  • 12
    Roderick HL, Berridge MJ & Bootman MD (2003) Calcium-induced calcium release. Curr Biol 13, R425.
  • 13
    Prole DL & Taylor CW (2011) Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites. PLoS One 6, e26218.
  • 14
    Ponting CP (2000) Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferases. Trends Biochem Sci 25, 4850.
  • 15
    Takeshima H, Nishimura S, Matsumoto T, Ishida H, Kangawa K, Minamino N, Matsuo H, Ueda M, Hanaoka M, Hirose T et al. (1989) Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. Nature 339, 439445.
  • 16
    Zorzato F, Fujii J, Otsu K, Phillips M, Green NM, Lai FA, Meissner G & MacLennan DH (1990) Molecular cloning of cDNA encoding human and rabbit forms of the Ca2 +  release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. J Biol Chem 265, 22442256.
  • 17
    Otsu K, Willard HF, Khanna VK, Zorzato F, Green NM & MacLennan DH (1990) Molecular cloning of cDNA encoding the Ca2 +  release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. J Biol Chem 265, 1347213483.
  • 18
    Nakai J, Imagawa T, Hakamat Y, Shigekawa M, Takeshima H & Numa S (1990) Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/calcium release channel. FEBS Lett 271, 169177.
  • 19
    Coussin F, Macrez N, Morel JL & Mironneau J (2000) Requirement of ryanodine receptor subtypes 1 and 2 for Ca(2 + )-induced Ca(2 + ) release in vascular myocytes. J Biol Chem 275, 95969603.
  • 20
    Giannini G, Conti A, Mammarella S, Scrobogna M & Sorrentino V (1995) The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. J Cell Biol 128, 893904.
  • 21
    Ottini L, Marziali G, Conti A, Charlesworth A & Sorrentino V (1996) Alpha and beta isoforms of ryanodine receptor from chicken skeletal muscle are the homologues of mammalian RyR1 and RyR3. Biochem J 315, 207216.
  • 22
    Oyamada H, Murayama T, Takagi T, Iino M, Iwabe N, Miyata T, Ogawa Y & Endo M (1994) Primary structure and distribution of ryanodine-binding protein isoforms of the bullfrog skeletal muscle. J Biol Chem 269, 1720617214.
  • 23
    Maryon EB, Coronado R & Anderson P (1996) unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction. J Cell Biol 134, 885893.
  • 24
    Takeshima H, Nishi M, Iwabe N, Miyata T, Hosoya T, Masai I & Hotta Y (1994) Isolation and characterization of a gene for a ryanodine receptor/calcium release channel in Drosophila melanogaster. FEBS Lett 337, 8187.
  • 25
    Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T & Mikoshiba K (2005) Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant. J Biol Chem 280, 1030510317.
  • 26
    De Smedt F, Verjans B, Mailleux P & Erneux C (1994) Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells. FEBS Lett 347, 6972.
  • 27
    Blondel O, Takeda J, Janssen H, Seino S & Bell GI (1993) Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues. J Biol Chem 268, 1135611363.
  • 28
    Bush KT, Stuart RO, Li SH, Moura LA, Sharp AH, Ross CA & Nigam SK (1994) Epithelial inositol 1,4,5-trisphosphate receptors. Multiplicity of localization, solubility, and isoforms. J Biol Chem 269, 2369423699.
  • 29
    De Smedt H, Missiaen L, Parys JB, Henning RH, Sienaert I, Vanlingen S, Gijsens A, Himpens B & Casteels R (1997) Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin. Biochem J 322, 575583.
  • 30
    Newton CL, Mignery GA & Sudhof TC (1994) Co-expression in vertebrate tissues and cell lines of multiple inositol 1,4,5-trisphosphate (InsP3) receptors with distinct affinities for InsP3. J Biol Chem 269, 2861328619.
  • 31
    Shibao K, Hirata K, Robert ME & Nathanson MH (2003) Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis. Gastroenterology 125, 11751187.
  • 32
    Takeshima H, Iino M, Takekura H, Nishi M, Kuno J, Minowa O, Takano H & Noda T (1994) Excitation–contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene. Nature 369, 556559.
  • 33
    Takeshima H, Komazaki S, Hirose K, Nishi M, Noda T & Iino M (1998) Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J 17, 33093316.
  • 34
    Takeshima H, Ikemoto T, Nishi M, Nishiyama N, Shimuta M, Sugitani Y, Kuno J, Saito I, Saito H, Endo M et al. (1996) Generation and characterization of mutant mice lacking ryanodine receptor type 3. J Biol Chem 271, 1964919652.
  • 35
    Futatsugi A, Kato K, Ogura H, Li ST, Nagata E, Kuwajima G, Tanaka K, Itohara S & Mikoshiba K (1999) Facilitation of NMDAR-independent LTP and spatial learning in mutant mice lacking ryanodine receptor type 3. Neuron 24, 701713.
  • 36
    Bertocchini F, Ovitt CE, Conti A, Barone V, Scholer HR, Bottinelli R, Reggiani C & Sorrentino V (1997) Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles. EMBO J 16, 69566963.
  • 37
    Matsuo N, Tanda K, Nakanishi K, Yamasaki N, Toyama K, Takao K, Takeshima H & Miyakawa T (2009) Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: decreased social contact duration in two social interaction tests. Front Behav Neurosci 3, 3.
  • 38
    Kouzu Y, Moriya T, Takeshima H, Yoshioka T & Shibata S (2000) Mutant mice lacking ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium/calmodulin-dependent protein kinase II in the hippocampus. Brain Res Mol Brain Res 76, 142150.
  • 39
    Balschun D, Wolfer DP, Bertocchini F, Barone V, Conti A, Zuschratter W, Missiaen L, Lipp HP, Frey JU & Sorrentino V (1999) Deletion of the ryanodine receptor type 3 (RyR3) impairs forms of synaptic plasticity and spatial learning. EMBO J 18, 52645273.
  • 40
    Matsumoto M, Nakagawa T, Inoue T, Nagata E, Tanaka K, Takano H, Minowa O, Kuno J, Sakakibara S, Yamada M et al. (1996) Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 379, 168171.
  • 41
    Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J et al. (2005) IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science 309, 22322234.
  • 42
    Fukuda N, Shirasu M, Sato K, Ebisui E, Touhara K & Mikoshiba K (2008) Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors. Eur J Neurosci 27, 26652675.
  • 43
    Yamazaki H, Nozaki H, Onodera O, Michikawa T, Nishizawa M & Mikoshiba K (2011) Functional characterization of the P1059L mutation in the inositol 1,4,5-trisphosphate receptor type 1 identified in a Japanese SCA15 family. Biochem Biophys Res Commun 410, 754758.
  • 44
    Lanner JT, Georgiou DK, Joshi AD & Hamilton SL (2010) Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Cold Spring Harb Perspect Biol 2, a003996.
  • 45
    Bezprozvanny I (2005) The inositol 1,4,5-trisphosphate receptors. Cell Calcium 38, 261272.
  • 46
    Cai X (2008) Unicellular Ca2 +  signaling ‘toolkit’ at the origin of metazoa. Mol Biol Evol 25, 13571361.
  • 47
    Cai X & Clapham DE (2012) Ancestral Ca2 +  signaling machinery in early animal and fungal evolution. Mol Biol Evol 29, 91100.
  • 48
    Mackrill JJ (2012) Ryanodine receptor calcium release channels: an evolutionary perspective. Adv Exp Med Biol 740, 159182.
  • 49
    Tung C-C, Lobo PA, Kimlicka L & Van Petegem F (2010) The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule. Nature 468, 585588.
  • 50
    Seo MD, Velamakanni S, Ishiyama N, Stathopulos PB, Rossi AM, Khan SA, Dale P, Li C, Ames JB, Ikura M et al. (2012) Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature 483, 108112.
  • 51
    Lin CC, Baek K & Lu Z (2011) Apo and InsP(3)-bound crystal structures of the ligand-binding domain of an InsP(3) receptor. Nat Struct Mol Biol 18, 11721174.
  • 52
    Bruno AM, Huang JY, Bennett DA, Marr RA, Hastings ML & Stutzmann GE (2012) Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 33, e1001e1006.
  • 53
    Berridge MJ (2011) Calcium signalling and Alzheimer's disease. Neurochem Res 36, 11491156.
  • 54
    Brandom BW, Larach MG, Chen MS & Young MC (2011) Complications associated with the administration of dantrolene 1987 to 2006: a report from the North American Malignant Hyperthermia Registry of the Malignant Hyperthermia Association of the United States. Anesth Analg 112, 11151123.
  • 55
    Durham WJ, Aracena-Parks P, Long C, Rossi AE, Goonasekera SA, Boncompagni S, Galvan DL, Gilman CP, Baker MR, Shirokova N et al. (2008) RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. Cell 133, 5365.
  • 56
    Hwang JH, Zorzato F, Clarke NF & Treves S (2012) Mapping domains and mutations on the skeletal muscle ryanodine receptor channel. Trends Mol Med 18, 644657.
  • 57
    Jurkat-Rott K, McCarthy T & Lehmann-Horn F (2000) Genetics and pathogenesis of malignant hyperthermia. Muscle Nerve 23, 417.
  • 58
    Avila G & Dirksen RT (2001) Functional effects of central core disease mutations in the cytoplasmic region of the skeletal muscle ryanodine receptor. J Gen Physiol 118, 277290.
  • 59
    Jungbluth H (2007) Central core disease. Orphanet J Rare Dis 2, 25.
  • 60
    Robinson RL, Brooks C, Brown SL, Ellis FR, Halsall PJ, Quinnell RJ, Shaw MA & Hopkins PM (2002) RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes. Hum Mutat 20, 8897.
  • 61
    Jungbluth H (2007) Multi-minicore disease. Orphanet J Rare Dis 2, 31.
  • 62
    Capacchione JF & Muldoon SM (2009) The relationship between exertional heat illness, exertional rhabdomyolysis, and malignant hyperthermia. Anesth Analg 109, 10651069.
  • 63
    Kolb ME, Horne ML & Martz R (1982) Dantrolene in human malignant hyperthermia. Anesthesiology 56, 254262.
  • 64
    Rosero EB, Adesanya AO, Timaran CH & Joshi GP (2009) Trends and outcomes of malignant hyperthermia in the United States, 2000 to 2005. Anesthesiology 110, 8994.
  • 65
    Paul-Pletzer K, Yamamoto T, Bhat MB, Ma J, Ikemoto N, Jimenez LS, Morimoto H, Williams PG & Parness J (2002) Identification of a dantrolene-binding sequence on the skeletal muscle ryanodine receptor. J Biol Chem 277, 3491834923.
  • 66
    Zhao F, Li P, Chen SR, Louis CF & Fruen BR (2001) Dantrolene inhibition of ryanodine receptor Ca2 +  release channels. Molecular mechanism and isoform selectivity. J Biol Chem 276, 1381013816.
  • 67
    MacLennan DH & Phillips MS (1992) Malignant hyperthermia. Science 256, 789794.
  • 68
    Sewry CA, Muller C, Davis M, Dwyer JS, Dove J, Evans G, Schroder R, Furst D, Helliwell T, Laing N et al. (2002) The spectrum of pathology in central core disease. Neuromuscul Disord 12, 930938.
  • 69
    Laitinen PJ, Brown KM, Piippo K, Swan H, Devaney JM, Brahmbhatt B, Donarum EA, Marino M, Tiso N, Viitasalo M et al. (2001) Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 103, 485490.
  • 70
    Lehnart SE, Wehrens XH, Laitinen PJ, Reiken SR, Deng SX, Cheng Z, Landry DW, Kontula K, Swan H & Marks AR (2004) Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak. Circulation 109, 32083214.
  • 71
    El Masry HZ & Yadav AV (2008) Arrhythmogenic right ventricular dysplasia/cardiomyopathy. Expert Rev Cardiovasc Ther 6, 249260.
  • 72
    Van Petegem F (2012) Ryanodine receptors: structure and function. J Biol Chem 287, 3162431632.
  • 73
    Tong J, Oyamada H, Demaurex N, Grinstein S, McCarthy TV & MacLennan DH (1997) Caffeine and halothane sensitivity of intracellular Ca2 +  release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease. J Biol Chem 272, 2633226339.
  • 74
    Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H & Chen SR (2004) RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2 +  release (SOICR). Proc Natl Acad Sci USA 101, 1306213067.
  • 75
    Tateishi H, Yano M, Mochizuki M, Suetomi T, Ono M, Xu X, Uchinoumi H, Okuda S, Oda T, Kobayashi S et al. (2009) Defective domain–domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2 +  leak in failing hearts. Cardiovasc Res 81, 536545.
  • 76
    Suetomi T, Yano M, Uchinoumi H, Fukuda M, Hino A, Ono M, Xu X, Tateishi H, Okuda S, Doi M et al. (2011) Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca2 +  release leading to catecholaminergic polymorphic ventricular tachycardia/clinical perspective. Circulation 124, 682694.
  • 77
    Ikemoto N & Yamamoto T (2000) Postulated role of inter-domain interaction within the ryanodine receptor in Ca(2 + ) channel regulation. Trends Cardiovasc Med 10, 310316.
  • 78
    Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N & Marks AR (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101, 365376.
  • 79
    Wehrens XH, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N et al. (2003) FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell 113, 829840.
  • 80
    Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW et al. (2008) Leaky Ca2 +  release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest 118, 22302245.
  • 81
    George CH, Higgs GV & Lai FA (2003) Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. Circ Res 93, 531540.
  • 82
    Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR & Bers DM (2010) Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res 106, 17431752.
  • 83
    Jiang D, Wang R, Xiao B, Kong H, Hunt DJ, Choi P, Zhang L & Chen SR (2005) Enhanced store overload-induced Ca2 +  release and channel sensitivity to luminal Ca2 +  activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death. Circ Res 97, 11731181.
  • 84
    Liu N, Colombi B, Memmi M, Zissimopoulos S, Rizzi N, Negri S, Imbriani M, Napolitano C, Lai FA & Priori SG (2006) Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model. Circ Res 99, 292298.
  • 85
    Xiao J, Tian X, Jones PP, Bolstad J, Kong H, Wang R, Zhang L, Duff HJ, Gillis AM, Fleischer S et al. (2007) Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias. J Biol Chem 282, 3482834838.
  • 86
    Karunasekara Y, Dulhunty AF & Casarotto MG (2009) The voltage-gated calcium-channel beta subunit: more than just an accessory. Eur Biophys J 39, 7581.
  • 87
    Wilkens CM, Kasielke N, Flucher BE, Beam KG & Grabner M (2001) Excitation–contraction coupling is unaffected by drastic alteration of the sequence surrounding residues L720–L764 of the alpha 1S II–III loop. Proc Natl Acad Sci USA 98, 58925897.
  • 88
    Tanabe T, Beam KG, Adams BA, Niidome T & Numa S (1990) Regions of the skeletal muscle dihydropyridine receptor critical for excitation–contraction coupling. Nature 346, 567569.
  • 89
    Kugler G, Weiss RG, Flucher BE & Grabner M (2004) Structural requirements of the dihydropyridine receptor alpha1S II–III loop for skeletal-type excitation–contraction coupling. J Biol Chem 279, 47214728.
  • 90
    Kugler G, Grabner M, Platzer J, Striessnig J & Flucher BE (2004) The monoclonal antibody mAB 1A binds to the excitation–contraction coupling domain in the II–III loop of the skeletal muscle calcium channel alpha(1S) subunit. Arch Biochem Biophys 427, 91100.
  • 91
    Carbonneau L, Bhattacharya D, Sheridan DC & Coronado R (2005) Multiple loops of the dihydropyridine receptor pore subunit are required for full-scale excitation–contraction coupling in skeletal muscle. Biophys J 89, 243255.
  • 92
    Dulhunty AF, Haarmann CS, Green D, Laver DR, Board PG & Casarotto MG (2002) Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle. Prog Biophys Mol Biol 79, 4575.
  • 93
    Karunasekara Y, Rebbeck RT, Weaver LM, Board PG, Dulhunty AF & Casarotto MG (2012) An alpha-helical C-terminal tail segment of the skeletal L-type Ca2 +  channel beta1a subunit activates ryanodine receptor type 1 via a hydrophobic surface. FASEB J. 26, 50495059.
  • 94
    Fabiato A (1983) Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol 245, C114.
  • 95
    Endo M, Tanaka M & Ogawa Y (1970) Calcium induced release of calcium from the sarcoplasmic reticulum of skinned skeletal muscle fibres. Nature 228, 3436.
  • 96
    Rios E & Brum G (1987) Involvement of dihydropyridine receptors in excitation–contraction coupling in skeletal muscle. Nature 325, 717720.
  • 97
    Damiani E & Margreth A (2000) Pharmacological clues to calmodulin-mediated activation of skeletal ryanodine receptor using [3H]-ryanodine binding. J Muscle Res Cell Motil 21, 18.
  • 98
    Rodney GG, Williams BY, Strasburg GM, Beckingham K & Hamilton SL (2000) Regulation of RYR1 activity by Ca(2 + ) and calmodulin. Biochemistry 39, 78077812.
  • 99
    Huang X, Fruen B, Farrington DT, Wagenknecht T & Liu Z (2012) Calmodulin-binding locations on the skeletal and cardiac ryanodine receptors. J Biol Chem 287, 3032830335.
  • 100
    Yamaguchi N, Xin C & Meissner G (2001) Identification of apocalmodulin and Ca2 + -calmodulin regulatory domain in skeletal muscle Ca2 +  release channel, ryanodine receptor. J Biol Chem 276, 2257922585.
  • 101
    Buratti R, Prestipino G, Menegazzi P, Treves S & Zorzato F (1995) Calcium dependent activation of skeletal muscle Ca2 +  release channel (ryanodine receptor) by calmodulin. Biochem Biophys Res Commun 213, 10821090.
  • 102
    Tripathy A, Xu L, Mann G & Meissner G (1995) Calmodulin activation and inhibition of skeletal muscle Ca2 +  release channel (ryanodine receptor). Biophys J 69, 106119.
  • 103
    Balshaw DM, Xu L, Yamaguchi N, Pasek DA & Meissner G (2001) Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor). J Biol Chem 276, 2014420153.
  • 104
    Yamaguchi N, Xu L, Pasek DA, Evans KE & Meissner G (2003) Molecular basis of calmodulin binding to cardiac muscle Ca(2 + ) release channel (ryanodine receptor). J Biol Chem 278, 2348023486.
  • 105
    Most P, Remppis A, Pleger ST, Loffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H et al. (2003) Transgenic overexpression of the Ca2 + -binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. J Biol Chem 278, 3380933817.
  • 106
    Prosser BL, Wright NT, Hernandez-Ochoa EO, Varney KM, Liu Y, Olojo RO, Zimmer DB, Weber DJ & Schneider MF (2008) S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation–contraction coupling. J Biol Chem 283, 50465057.
  • 107
    Maximciuc AA, Putkey JA, Shamoo Y & Mackenzie KR (2006) Complex of calmodulin with a ryanodine receptor target reveals a novel, flexible binding mode. Structure 14, 15471556.
  • 108
    Wright NT, Prosser BL, Varney KM, Zimmer DB, Schneider MF & Weber DJ (2008) S100A1 and calmodulin compete for the same binding site on ryanodine receptor. J Biol Chem 283, 2667626683.
  • 109
    Prosser BL, Hernandez-Ochoa EO & Schneider MF (2011) S100A1 and calmodulin regulation of ryanodine receptor in striated muscle. Cell Calcium 50, 323331.
  • 110
    Amador FJ, Liu S, Ishiyama N, Plevin MJ, Wilson A, MacLennan DH & Ikura M (2009) Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation ‘hot spot’ loop. Proc Natl Acad Sci USA 106, 1104011044.
  • 111
    Lobo PA & Van Petegem F (2009) Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations. Structure 17, 15051514.
  • 112
    Lobo PA, Kimlicka L, Tung CC & Van Petegem F (2011) The deletion of exon 3 in the cardiac ryanodine receptor is rescued by beta strand switching. Structure 19, 790798.
  • 113
    Sharma P, Ishiyama N, Nair U, Li W, Dong A, Miyake T, Wilson A, Ryan T, Maclennan DH, Kislinger T et al. (2012) Structural determination of the phosphorylation domain of the ryanodine receptor. FEBS J 279, 39523964.
  • 114
    Yuchi Z, Lau K & Van Petegem F (2012) Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain. Structure 20, 12011211.
  • 115
    White RR, Kwon YG, Taing M, Lawrence DS & Edelman AM (1998) Definition of optimal substrate recognition motifs of Ca2 + -calmodulin-dependent protein kinases IV and II reveals shared and distinctive features. J Biol Chem 273, 31663172.
  • 116
    Ponting C, Schultz J & Bork P (1997) SPRY domains in ryanodine receptors (Ca(2 + )-release channels). Trends Biochem Sci 22, 193194.
  • 117
    Tae H, Casarotto MG & Dulhunty AF (2009) Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor. Eur Biophys J 39, 5159.
  • 118
    Casarotto MG, Cui Y, Karunasekara Y, Harvey PJ, Norris N, Board PG & Dulhunty AF (2006) Structural and functional characterization of interactions between the dihydropyridine receptor II–III loop and the ryanodine receptor. Clin Exp Pharmacol Physiol 33, 11141117.
  • 119
    Kimura T, Pace SM, Wei L, Beard NA, Dirksen RT & Dulhunty AF (2007) A variably spliced region in the type 1 ryanodine receptor may participate in an inter-domain interaction. Biochem J 401, 317324.
  • 120
    Cui Y, Tae HS, Norris NC, Karunasekara Y, Pouliquin P, Board PG, Dulhunty AF & Casarotto MG (2009) A dihydropyridine receptor alpha1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor. Int J Biochem Cell Biol 41, 677686.
  • 121
    Tae HS, Cui Y, Karunasekara Y, Board PG, Dulhunty AF & Casarotto MG (2011) Cyclization of the intrinsically disordered alpha1S dihydropyridine receptor II–III loop enhances secondary structure and in vitro function. J Biol Chem 286, 2258922599.
  • 122
    Dulhunty AF, Karunasekara Y, Curtis SM, Harvey PJ, Board PG & Casarotto MG (2005) The recombinant dihydropyridine receptor II–III loop and partly structured ‘C’ region peptides modify cardiac ryanodine receptor activity. Biochem J 385, 803813.
  • 123
    Lu X, Xu L & Meissner G (1994) Activation of the skeletal muscle calcium release channel by a cytoplasmic loop of the dihydropyridine receptor. J Biol Chem 269, 65116516.
  • 124
    Stange M, Tripathy A & Meissner G (2001) Two domains in dihydropyridine receptor activate the skeletal muscle Ca(2 + ) release channel. Biophys J 81, 14191429.
  • 125
    Rebbeck RT, Karunasekara Y, Gallant EM, Board PG, Beard NA, Casarotto MG & Dulhunty AF (2011) The beta(1a) subunit of the skeletal DHPR binds to skeletal RyR1 and activates the channel via its 35-residue C-terminal tail. Biophys J 100, 922930.
  • 126
    Sheridan DC, Cheng W, Carbonneau L, Ahern CA & Coronado R (2004) Involvement of a heptad repeat in the carboxyl terminus of the dihydropyridine receptor beta1a subunit in the mechanism of excitation–contraction coupling in skeletal muscle. Biophys J 87, 929942.
  • 127
    Neuhuber B, Gerster U, Doring F, Glossmann H, Tanabe T & Flucher BE (1998) Association of calcium channel alpha1S and beta1a subunits is required for the targeting of beta1a but not of alpha1S into skeletal muscle triads. Proc Natl Acad Sci USA 95, 50155020.
  • 128
    Leuranguer V, Papadopoulos S & Beam KG (2006) Organization of calcium channel beta1a subunits in triad junctions in skeletal muscle. J Biol Chem 281, 35213527.
  • 129
    Radermacher M, Rao V, Grassucci R, Frank J, Timerman AP, Fleischer S & Wagenknecht T (1994) Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle. J Cell Biol 127, 411423.
  • 130
    Serysheva II, Orlova EV, Chiu W, Sherman MB, Hamilton SL & van Heel M (1995) Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel. Nat Struct Biol 2, 1824.
  • 131
    Ludtke SJ, Serysheva II, Hamilton SL & Chiu W (2005) The pore structure of the closed RyR1 channel. Structure 13, 12031211.
  • 132
    Samso M, Wagenknecht T & Allen PD (2005) Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat Struct Mol Biol 12, 539544.
  • 133
    Serysheva II, Ludtke SJ, Baker ML, Cong Y, Topf M, Eramian D, Sali A, Hamilton SL & Chiu W (2008) Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci USA 105, 96109615.
  • 134
    Samso M, Feng W, Pessah IN & Allen PD (2009) Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol 7, e85.
  • 135
    Kimlicka L & Van Petegem F (2011) The structural biology of ryanodine receptors. Sci China Life Sci 54, 712724.
  • 136
    Raina SA, Tsai J, Samso M & Fessenden JD (2012) FRET-based localization of fluorescent protein insertions within the ryanodine receptor type 1. PLoS One 7, e38594.
  • 137
    Meng X, Xiao B, Cai S, Huang X, Li F, Bolstad J, Trujillo R, Airey J, Chen SR, Wagenknecht T et al. (2007) Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor. J Biol Chem 282, 2592925939.
  • 138
    Yin CC, D'Cruz LG & Lai FA (2008) Ryanodine receptor arrays: not just a pretty pattern? Trends Cell Biol 18, 149156.
  • 139
    Yin CC & Lai FA (2000) Intrinsic lattice formation by the ryanodine receptor calcium-release channel. Nat Cell Biol 2, 669671.
  • 140
    Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Chiu W & Serysheva II (2011) Flexible architecture of IP3R1 by cryo-EM. Structure 19, 11921199.
  • 141
    Yuchi Z & Van Petegem F (2011) Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors. Channels (Austin) 5, 120123.
  • 142
    Mikoshiba K (2007) The IP3 receptor/Ca2+ channel and its cellular function. Biochem Soc Symp 74, 922.
  • 143
    Boehning D & Joseph SK (2000) Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors. EMBO J 19, 54505459.
  • 144
    Edgar RC (2004) MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 32, 17921797.
  • 145
    Tamura K, Peterson D, Peterson N, Stecher G, Nei M & Kumar S (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28, 27312739.