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Fig. S1. Calibration curve for molecular weight (MW) determination of C. elegans and A. suum DcpS proteins obtained by means of gel filtration.

Data S1. Materials and methods.

Table S1. Specificity and binding affinity of human DcpS towards cap analogs, determined in the same experimental conditions as for C. elegans DcpS: 50 mm Tris/HCl buffer containing 200 mm KCl, 0.5 mm EDTA and 1 mm dithiothreitol (pH 7.6), at 20 °C.

Table S2. Sampling parameters used in all docking experiments with autodock 4.2.

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