The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca
Article first published online: 7 APR 2014
© 2014 The Authors. FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 281, Issue 9, pages 2240–2253, May 2014
How to Cite
Sayer, C., Martinez-Torres, R. J., Richter, N., Isupov, M. N., Hailes, H. C., Littlechild, J. A. and Ward, J. M. (2014), The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca. FEBS Journal, 281: 2240–2253. doi: 10.1111/febs.12778
- Issue published online: 1 MAY 2014
- Article first published online: 7 APR 2014
- Accepted manuscript online: 11 MAR 2014 01:12PM EST
- Manuscript Accepted: 5 MAR 2014
- Manuscript Revised: 3 MAR 2014
- Manuscript Received: 29 JAN 2014
- EPSRC. Grant Number: EP/G005834/1
- ERA-IB. Grant Number: BB/L002035/1
- Wellcome Trust
Fig. S1. Representation of synthetic gene design.
Fig. S2. Enzyme activity of the Nectria TAm synthetic genes.
Table S1. Chiral HPLC details for chiral amines prepared using Nectria TAm.
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