Pathogens and Disease

Cover image for Pathogens and Disease

March 2013

Volume 67, Issue 2

Pages i–ii, 89–158

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. Issue Information (pages i–ii)

      Version of Record online: 11 MAR 2013 | DOI: 10.1111/j.1574-695X.2012.01016.x

  2. Letter to the Editor

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. In Chlamydia veritas (pages 89–90)

      Patrik Bavoil, Bernard Kaltenboeck and Gilbert Greub

      Version of Record online: 12 FEB 2013 | DOI: 10.1111/2049-632X.12026

  3. Molecular Pathogenesis

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. Research Article

      Colonization of gerbils with Helicobacter pylori O-chain-deficient mutant SS1 HP0826::Kan results in gastritis and is associated with de novo synthesis of extended homopolymers (pages 91–99)

      Vandana Chandan, Anthony H.T. Jeremy, Michael F. Dixon, Eleonora Altman and Jean E. Crabtree

      Version of Record online: 25 FEB 2013 | DOI: 10.1111/2049-632X.12021

      This article investigates the role of lipopolysaccharide O-antigen in Helicobacter pylori colonization and gastritis in Mongolian gerbils, with contrasting findings to those in mouse models, and indicates that adaptation in LPS polysaccharide composition may promote H. pylori infection.

    2. Short Communications

      You have full text access to this OnlineOpen article
      Transformation of a plasmid-free, genital tract isolate of Chlamydia trachomatis with a plasmid vector carrying a deletion in CDS6 revealed that this gene regulates inclusion phenotype (pages 100–103)

      Yibing Wang, Lesley T. Cutcliffe, Rachel J. Skilton, Kenneth Persson, Carina Bjartling and Ian N. Clarke

      Version of Record online: 13 FEB 2013 | DOI: 10.1111/2049-632X.12024

      The revised manuscript is a short, definitive manuscript which applies new DNA transformation technologies to Chlamydia to address the function of plasmid genes in glycogen metabolism.

    3. Proteus mirabilis uroepithelial cell adhesin (UCA) fimbria plays a role in the colonization of the urinary tract (pages 104–107)

      Rafael Pellegrino, Paola Scavone, Ana Umpiérrez, Duncan J. Maskell and Pablo Zunino

      Version of Record online: 21 FEB 2013 | DOI: 10.1111/2049-632X.12027

      This work is highly significant as it verifies using relevant in vivo infection models that the Proteus mirabilis uroepithelial cell adhesin (UCA) fimbria is indeed of great importance for colonization of the urinary tract.

  4. Host Responses to Infection and Diseases

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. MiniReview

      Autophagy as an innate defense against mycobacteria (pages 108–118)

      Eun-Kyeong Jo

      Version of Record online: 21 FEB 2013 | DOI: 10.1111/2049-632X.12023

      A contemporary, comprehensive and timely review of autophagy in mycobacterial infections with particular relevance to tuberculosis. A review of this proportion supported by excellent figures has long been needed.

    2. Research Article

      Pili play an important role in enhancing the bacterial clearance from the middle ear in a mouse model of acute otitis media with Moraxella catarrhalis (pages 119–131)

      Toshiaki Kawano, Takashi Hirano, Satoru Kodama, Marcelo Takahiro Mitsui, Kamruddin Ahmed, Akira Nishizono and Masashi Suzuki

      Version of Record online: 26 FEB 2013 | DOI: 10.1111/2049-632X.12025

      This article describes an experimental murine acute otitis media model of Moraxella catarrhalis infection, and finds that expression of pili by this bacterial pathogen influences the infection by stimulating innate immune signaling.

  5. Shortomics

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. Short Communication

      Bordetella holmesii: initial genomic analysis of an emerging opportunist (pages 132–135)

      Paul J. Planet, Apurva Narechania, Saul R. Hymes, Christina Gagliardo, Richard C. Huard, Susan Whittier, Phyllis Della-Latta and Adam J. Ratner

      Version of Record online: 26 FEB 2013 | DOI: 10.1111/2049-632X.12028

      An inexpensive draft genome of Bordetella holmesii reveals unsuspected phylogeny, virulence factors of this emerging pathogen, and a predicted toluene-4-monoxygenase.

  6. Translational Research

    1. Top of page
    2. Issue Information
    3. Letter to the Editor
    4. Molecular Pathogenesis
    5. Host Responses to Infection and Diseases
    6. Shortomics
    7. Translational Research
    1. Research Article

      Acid-detoxified Inaba lipopolysaccharide (pmLPS) is a superior cholera conjugate vaccine immunogen than hydrazine-detoxified lipopolysaccharide and induces vibriocidal and protective antibodies (pages 136–158)

      Cyrille Grandjean, Terri K. Wade, David Ropartz, Logan Ernst and William F. Wade

      Version of Record online: 25 FEB 2013 | DOI: 10.1111/2049-632X.12022

      Vibrio cholerae continues to be a major disease worldwide and requires improved vaccines. This study reports the use of an experimental Vibrio cholerae Inaba LPS-protein conjugate vaccine and shows that pmLPS is a superior immunogen and a viable potential vaccine candidate.

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