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FEMS Microbiology Letters

Cover image for Vol. 351 Issue 2

Special Issue: Systems and Synthetic Biology

February 2014

Volume 351, Issue 2

Pages i–iii, 113–215

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
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      Issue Information (pages i–iii)

      Version of Record online: 24 FEB 2014 | DOI: 10.1111/1574-6968.12252

  2. Editorial

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
    1. You have free access to this content
  3. MiniReviews

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
    1. You have full text access to this OnlineOpen article
      Steps towards the synthetic biology of polyketide biosynthesis (pages 116–125)

      Matthew Cummings, Rainer Breitling and Eriko Takano

      Version of Record online: 7 JAN 2014 | DOI: 10.1111/1574-6968.12365

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      This authors discuss how traditional molecular biology contributed to understanding and engineering polyketide biosynthesis and how it can now be combined with recent advances in synthetic biology to create new antibiotics.

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      ‘Drugs from Bugs’: bacterial effector proteins as promising biological (immune-) therapeutics (pages 126–132)

      Christian Rüter and Philip R. Hardwidge

      Version of Record online: 11 DEC 2013 | DOI: 10.1111/1574-6968.12333

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      The diversity of bacterial effector proteins provides a rich toolkit for therapeutic or biotechnological applications.

  4. Perspective

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
    1. You have full text access to this OnlineOpen article
      Sense codon emancipation for proteome-wide incorporation of noncanonical amino acids: rare isoleucine codon AUA as a target for genetic code expansion (pages 133–144)

      Nina Bohlke and Nediljko Budisa

      Version of Record online: 27 JAN 2014 | DOI: 10.1111/1574-6968.12371

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      Sense codon emancipation and codon reassignment: a synthetic biology approach to the extension of the universal genetic code.

  5. Current Controversy in Microbiology

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
    1. You have free access to this content
      How many 16S-based studies should be included in a metagenomic conference? It may be a matter of etymology (pages 145–146)

      Alfonso Esposito and Matthias Kirschberg

      Version of Record online: 30 JAN 2014 | DOI: 10.1111/1574-6968.12375

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      DNA extracted from the environment contains a mixture of DNA belonging to all organisms regardless of their exact location (stones, soil, or plants) and therefore is named ‘metagenomic’. Metagenomic DNA can be used to make studies on single genes, and this kind of study is named ‘metagenetics’.

  6. Research Letters

    1. Top of page
    2. Issue Information
    3. Editorial
    4. MiniReviews
    5. Perspective
    6. Current Controversy in Microbiology
    7. Research Letters
    1. You have free access to this content
      Discovery of two novel β-glucosidases from an Amazon soil metagenomic library (pages 147–155)

      Jessica C. Bergmann, Ohana Yonara A. Costa, John M. Gladden, Steven Singer, Richard Heins, Patrik D'haeseleer, Blake A. Simmons and Betania F. Quirino

      Version of Record online: 16 DEC 2013 | DOI: 10.1111/1574-6968.12332

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      Two novel beta-glucosidase enzymes were found through a functional screening of a metagenomic library constructed from total DNA isolation of Amazon soil. One of the enzymes was successfully purified and chemically characterized. This is the first report of β-glucosidase discovery using a metagenomic approach from an Amazon soil microbial community.

    2. You have full text access to this OnlineOpen article
      Bacteriophage T4 can produce progeny virions in extremely slowly growing Escherichia coli host: comparison of a mathematical model with the experimental data (pages 156–161)

      Piotr Golec, Joanna Karczewska-Golec, Marcin Łoś and Grzegorz Węgrzyn

      Version of Record online: 20 JAN 2014 | DOI: 10.1111/1574-6968.12372

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      Bacteriophage T4 is able to give progeny in host Escherichia coli cells that grow with a doubling time as long as 21 h.

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      Selection of a DNA aptamer against norovirus capsid protein VP1 (pages 162–169)

      Rico Beier, Claudia Pahlke, Philipp Quenzel, Anja Henseleit, Elke Boschke, Gianaurelio Cuniberti and Dirk Labudde

      Version of Record online: 13 JAN 2014 | DOI: 10.1111/1574-6968.12366

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      The article describes the process of finding an aptamer against the norovirus capsid using experiments and analysis, thus establishing a link between molecular biology and bioinformatics.

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      Recombinant protein expression in Lactococcus lactis using the P170 expression system (pages 170–178)

      Casper M. Jørgensen, Astrid Vrang and Søren M. Madsen

      Version of Record online: 19 DEC 2013 | DOI: 10.1111/1574-6968.12351

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      This study describes the development of a simple production system for manufacturing recombinant proteins and enzymes in a safe bacterial host.

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      Sensitivity of bacteria to diamond nanoparticles of various size differs in gram-positive and gram-negative cells (pages 179–186)

      Jana Beranová, Gabriela Seydlová, Halyna Kozak, Oldřich Benada, Radovan Fišer, Anna Artemenko, Ivo Konopásek and Alexander Kromka

      Version of Record online: 31 JAN 2014 | DOI: 10.1111/1574-6968.12373

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      The antibacterial activity of diamond nanoparticles depends both on the size and surface termination of the nanoparticles and also on the structure of the bacterial cell wall.

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      The communities of tomato (Solanum lycopersicum L.) leaf endophytic bacteria, analyzed by 16S-ribosomal RNA gene pyrosequencing (pages 187–194)

      Fernando M. Romero, María Marina and Fernando L. Pieckenstain

      Version of Record online: 3 FEB 2014 | DOI: 10.1111/1574-6968.12377

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      A culture-independent approach was used to analyze the structure and diversity of bacterial communities that endophytically colonize leaves of cultivated tomato.

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      Comparison of the effects of silver phosphate and selenium nanoparticles on Staphylococcus aureus growth reveals potential for selenium particles to prevent infection (pages 195–201)

      Dagmar Chudobova, Kristyna Cihalova, Simona Dostalova, Branislav Ruttkay-Nedecky, Miguel Angel Merlos Rodrigo, Katerina Tmejova, Pavel Kopel, Lukas Nejdl, Jiri Kudr, Jaromir Gumulec, Sona Krizkova, Jindrich Kynicky, Rene Kizek and Vojtech Adam

      Version of Record online: 30 DEC 2013 | DOI: 10.1111/1574-6968.12353

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      Inhibition of Staphylococcus aureus growth by selenium, but not silver, nanoparticles offers scope for controlling infection.

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      Expression of Porphyromonas gingivalis small RNA in response to hemin availability identified using microarray and RNA-seq analysis (pages 202–208)

      Priscilla Phillips, Ann Progulske-Fox, Scott Grieshaber and Nicole Grieshaber

      Version of Record online: 19 NOV 2013 | DOI: 10.1111/1574-6968.12320

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      RNA expressed in the oral pathogen Porphyromonas gingivalis in response to hemin availability and growth phase were comparatively analyzed to identify regulatory small RNAs.

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      Novel Amycolatopsis balhimycina biochemical abilities unveiled by proteomics (pages 209–215)

      Rosa Alduina, Giuseppe Gallo, Gianni Renzone, Tilmann Weber, Andrea Scaloni and Anna M. Puglia

      Version of Record online: 19 NOV 2013 | DOI: 10.1111/1574-6968.12324

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      A 1DE-proteomic approach was used to implement proteomic data on the vancomycin-producing actinomycete Amycolatopsis balhimycina

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