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  • Anacker, C., Zunszain, P.A., Carvalho, L.A. & Pariante, C.M. (2011) The glucocorticoid receptor: pivot of depression and of antidepressant treatment? Psychoneuroendocrinology 36, 415425.
  • Appel, K., Schwahn, C., Mahler, J., Schulz, A., Spitzer, C., Fenske, K., Stender, J., Barnow, S., John, U., Teumer, A., Biffar, R., Nauck, M., Volzke, H., Freyberger, H.J. & Grabe, H.J. (2011) Moderation of adult depression by a polymorphism in the FKBP5 gene and childhood physical abuse in the general population. Neuropsychopharmacology 36, 19821991.
  • Binder, E.B. (2009) The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 34 (Suppl. 1), S186S195.
  • Binder, E.B., Salyakina, D., Lichtner, P. et al. (2004) Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet 36, 13191325.
  • Binder, E.B., Bradley, R.G., Liu, W., Epstein, M.P., Deveau, T.C., Mercer, K.B., Tang, Y., Gillespie, C.F., Heim, C.M., Nemeroff, C.B., Schwartz, A.C., Cubells, J.F. & Ressler, K.J. (2008) Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299, 12911305.
  • Binder, E.B., Kunzel, H.E., Nickel, T., Kern, N., Pfennig, A., Majer, M., Uhr, M., Ising, M. & Holsboer, F. (2009) HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients. Psychoneuroendocrinology 34, 99109.
  • Brent, D., Melhem, N., Ferrell, R., Emslie, G., Wagner, K.D., Ryan, N., Vitiello, B., Birmaher, B., Mayes, T., Zelazny, J., Onorato, M., Devlin, B., Clarke, G., DeBar, L. & Keller, M. (2010) Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study. Am J Psychiatry 167, 190197.
  • Carpenter, L.L., Ross, N.S., Tyrka, A.R., Anderson, G.M., Kelly, M. & Price, L.H. (2009) Dex/CRH test cortisol response in outpatients with major depression and matched healthy controls. Psychoneuroendocrinology 34, 12081213.
  • Hartmann, J., Wagner, K.V., Liebl, C., Scharf, S.H., Wang, X.D., Wolf, M., Hausch, F., Rein, T., Schmidt, U., Touma, C., Cheung-Flynn, J., Cox, M.B., Smith, D.F., Holsboer, F., Muller, M.B. & Schmidt, M.V. (2012) The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress. Neuropharmacology 62, 332339.
  • Heim, C. & Nemeroff, C.B. (2001) The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 49, 10231039.
  • Heiske, A., Jesberg, J., Krieg, J.C. & Vedder, H. (2003) Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells. Neuropsychopharmacology 28, 807817.
  • Hennings, J.M., Owashi, T., Binder, E.B. et al. (2009) Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. J Psychiatr Res 43, 215229.
  • Holsboer, F. (2000) The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 23, 477501.
  • Ising, M., Horstmann, S., Kloiber, S., Lucae, S., Binder, E.B., Kern, N., Kunzel, H.E., Pfennig, A., Uhr, M. & Holsboer, F. (2007) Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker? Biol Psychiatry 62, 4754.
  • Ising, M., Depping, A.M., Siebertz, A., Lucae, S., Unschuld, P.G., Kloiber, S., Horstmann, S., Uhr, M., Muller-Myhsok, B. & Holsboer, F. (2008) Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls. Eur J Neurosci 28, 389398.
  • Ising, M., Lucae, S., Binder, E.B., Bettecken, T., Uhr, M., Ripke, S., Kohli, M.A., Hennings, J.M., Horstmann, S., Kloiber, S., Menke, A., Bondy, B., Rupprecht, R., Domschke, K., Baune, B.T., Arolt, V., Rush, A.J., Holsboer, F. & Muller-Myhsok, B. (2009) A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry 66, 966975.
  • Jaaskelainen, T., Makkonen, H. & Palvimo, J.J. (2011) Steroid up-regulation of FKBP51 and its role in hormone signaling. Curr Opin Pharmacol 11, 326331.
  • Klengel, T., Mehta, D., Anacker, C., Rex-Haffner, M., Pruessner, J.C., Pariante, C.M., Pace, T.W., Mercer, K.B., Mayberg, H.S., Bradley, B., Nemeroff, C.B., Holsboer, F., Heim, C.M., Ressler, K.J., Rein, T. & Binder, E.B. (2013) Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci 16, 3341.
  • de Kloet, E.R., Joels, M. & Holsboer, F. (2005) Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6, 463475.
  • Kohli, M.A., Lucae, S., Saemann, P. et al. (2011) The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron 70, 252265.
  • Kunzel, H.E., Binder, E.B., Nickel, T., Ising, M., Fuchs, B., Majer, M., Pfennig, A., Ernst, G., Kern, N., Schmid, D.A., Uhr, M., Holsboer, F. & Modell, S. (2003) Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test. Neuropsychopharmacology 28, 21692178.
  • Lavebratt, C., Aberg, E., Sjoholm, L.K. & Forsell, Y. (2010) Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort. J Affect Disord 125, 249255.
  • Lee, R.S., Tamashiro, K.L., Yang, X., Purcell, R.H., Harvey, A., Willour, V.L., Huo, Y., Rongione, M., Wand, G.S. & Potash, J.B. (2010) Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice. Endocrinology 151, 43324343.
  • Lee, R.S., Tamashiro, K.L., Yang, X., Purcell, R.H., Huo, Y., Rongione, M., Potash, J.B. & Wand, G.S. (2011) A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice. Psychopharmacology (Berl) 218, 303312.
  • Lekman, M., Laje, G., Charney, D., Rush, A.J., Wilson, A.F., Sorant, A.J., Lipsky, R., Wisniewski, S.R., Manji, H., McMahon, F.J. & Paddock, S. (2008) The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biol Psychiatry 63, 11031110.
  • Lok, A., Mocking, R.J., Ruhe, H.G., Visser, I., Koeter, M.W., Assies, J., Bockting, C.L., Olff, M. & Schene, A.H. (2012) Longitudinal hypothalamic-pituitary-adrenal axis trait and state effects in recurrent depression. Psychoneuroendocrinology 37, 892902.
  • Luijk, M.P., Velders, F.P., Tharner, A., van Ijzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W., Hofman, A., Verhulst, F.C. & Tiemeier, H. (2010) FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction. Psychoneuroendocrinology 35, 14541461.
  • Manenschijn, L., Spijker, A.T., Koper, J.W., Jetten, A.M., Giltay, E.J., Haffmans, J., Hoencamp, E. & van Rossum, E.F. (2012) Long-term cortisol in bipolar disorder: Associations with age of onset and psychiatric co-morbidity. Psychoneuroendocrinology 37, 19601968.
  • McGirr, A., Diaconu, G., Berlim, M.T. & Turecki, G. (2011) Personal and family history of suicidal behaviour is associated with lower peripheral cortisol in depressed outpatients. J Affect Disord 131, 368373.
  • Mehta, D., Gonik, M., Klengel, T., Rex-Haffner, M., Menke, A., Rubel, J., Mercer, K.B., Putz, B., Bradley, B., Holsboer, F., Ressler, K.J., Muller-Myhsok, B. & Binder, E.B. (2011) Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Arch Gen Psychiatry 68, 901910.
  • Menke, A., Arloth, J., Putz, B., Weber, P., Klengel, T., Mehta, D., Gonik, M., Rex-Haffner, M., Rubel, J., Uhr, M., Lucae, S., Deussing, J.M., Muller-Myhsok, B., Holsboer, F. & Binder, E.B. (2012a) Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients. Neuropsychopharmacology 37, 14551464.
  • Menke, A., Rex-Haffner, M., Klengel, T., Binder, E.B. & Mehta, D. (2012b) Peripheral blood gene expression: it all boils down to the RNA collection tubes. BMC Res Notes 5, 1.
  • Pariante, C.M. & Miller, A.H. (2001) Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry 49, 391404.
  • Reynolds, P.D., Ruan, Y., Smith, D.F. & Scammell, J.G. (1999) Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. J Clin Endocrinol Metab 84, 663669.
  • Roy, A., Gorodetsky, E., Yuan, Q., Goldman, D. & Enoch, M.A. (2010) Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide. Neuropsychopharmacology 35, 16741683.
  • Ruijter, J.M., Ramakers, C., Hoogaars, W.M., Karlen, Y., Bakker, O., van den Hoff, M.J. & Moorman, A.F. (2009) Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data. Nucleic Acids Res 37, e45.
  • Sanchez, E.R. (1990) Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes. J Biol Chem 265, 2206722070.
  • Sarapas, C., Cai, G., Bierer, L.M., Golier, J.A., Galea, S., Ising, M., Rein, T., Schmeidler, J., Muller-Myhsok, B., Uhr, M., Holsboer, F., Buxbaum, J.D. & Yehuda, R. (2011) Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks. Dis Markers 30, 101110.
  • Scharf, S.H., Liebl, C., Binder, E.B., Schmidt, M.V. & Muller, M.B. (2011) Expression and regulation of the Fkbp5 gene in the adult mouse brain. PLoS One 6, e16883.
  • Smith, D.F., Faber, L.E. & Toft, D.O. (1990) Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins. J Biol Chem 265, 39964003.
  • Storer, C.L., Dickey, C.A., Galigniana, M.D., Rein, T. & Cox, M.B. (2011) FKBP51 and FKBP52 in signaling and disease. Trends Endocrinol Metab 22, 481490.
  • Supriyanto, I., Sasada, T., Fukutake, M., Asano, M., Ueno, Y., Nagasaki, Y., Shirakawa, O. & Hishimoto, A. (2010) Association of FKBP5 gene haplotypes with completed suicide in the Japanese population. Prog Neuropsychopharmacol Biol Psychiatry 35, 252256.
  • Touma, C., Gassen, N.C., Herrmann, L., Cheung-Flynn, J., Bull, D.R., Ionescu, I.A., Heinzmann, J.M., Knapman, A., Siebertz, A., Depping, A.M., Hartmann, J., Hausch, F., Schmidt, M.V., Holsboer, F., Ising, M., Cox, M.B., Schmidt, U. & Rein, T. (2011) FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior. Biol Psychiatry 70, 928936.
  • Velders, F.P., Kuningas, M., Kumari, M., Dekker, M.J., Uitterlinden, A.G., Kirschbaum, C., Hek, K., Hofman, A., Verhulst, F.C., Kivimaki, M., Van Duijn, C.M., Walker, B.R. & Tiemeier, H. (2011) Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology 36, 10531061.
  • Vermeer, H., Hendriks-Stegeman, B.I., van Suylekom, D., Rijkers, G.T., van Buul-Offers, S.C. & Jansen, M. (2004) An in vitro bioassay to determine individual sensitivity to glucocorticoids: induction of FKBP51 mRNA in peripheral blood mononuclear cells. Mol Cell Endocrinol 218, 4955.
  • Vreeburg, S.A., Hoogendijk, W.J., van Pelt, J., Derijk, R.H., Verhagen, J.C., van Dyck, R., Smit, J.H., Zitman, F.G. & Penninx, B.W. (2009) Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Arch Gen Psychiatry 66, 617626.
  • White, M.G., Bogdan, R., Fisher, P.M., Munoz, K.E., Williamson, D.E. & Hariri, A.R. (2012) FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. Genes Brain Behav 11, 869878.
  • Willour, V.L., Chen, H., Toolan, J., Belmonte, P., Cutler, D.J., Goes, F.S., Zandi, P.P., Lee, R.S., Mackinnon, D.F., Mondimore, F.M., Schweizer, B., Depaulo, J.R. Jr., Gershon, E.S., McMahon, F.J. & Potash, J.B. (2008) Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry 14, 261268.
  • Wittchen, H.U., Höfler, M., Gander, F., Pfister, H., Storz, S., Üstün, T.B., Müller, N. & Kessler, R.C. (1999) Screening for mental disorders: performance of the Composite International Diagnostic - Screener (CID-S). Int J Methods Psychiatr Res 8, 5970.
  • Xie, P., Kranzler, H.R., Poling, J., Stein, M.B., Anton, R.F., Farrer, L.A. & Gelernter, J. (2010) Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology 35, 16841692.
  • Yang, X., Ewald, E.R., Huo, Y., Tamashiro, K.L., Salvatori, R., Sawa, A., Wand, G.S. & Lee, R.S. (2012) Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochem Biophys Res Commun 420, 570575.
  • Yehuda, R., Golier, J.A., Halligan, S.L., Meaney, M. & Bierer, L.M. (2004) The ACTH response to dexamethasone in PTSD. Am J Psychiatry 161, 13971403.
  • Zimmermann, P., Bruckl, T., Nocon, A., Pfister, H., Binder, E.B., Uhr, M., Lieb, R., Moffitt, T.E., Caspi, A., Holsboer, F. & Ising, M. (2011) Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. Am J Psychiatry 168, 11071116.
  • Zobel, A., Schuhmacher, A., Jessen, F., Hofels, S., von Widdern, O., Metten, M., Pfeiffer, U., Hanses, C., Becker, T., Rietschel, M., Scheef, L., Block, W., Schild, H.H., Maier, W. & Schwab, S.G. (2010) DNA sequence variants of the FKBP5 gene are associated with unipolar depression. Int J Neuropsychopharmacol 13, 649660.