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Antimicrobial activity and surface properties of an acrylic resin containing a biocide polymer

Authors

  • Marco A. Compagnoni,

    Corresponding author
    1. Department of Dental Materials and Prosthodontics, Araraquara Dental School, Univ Estadual Paulista - UNESP, Araraquara, São Paulo, Brazil
    • Correspondence to:

      Dr Marco Antonio Compagnoni,

      Department of Dental Materials and Prosthodontics,

      Araraquara Dental School, UNESP,

      Univ Estadual Paulista, Rua Humaitá 1680,

      14801-903 Araraquara, SP, Brazil.

      Tel.: +55 16 33016411

      Fax: +55 16 33016406

      E-mail: compagno@foar.unesp.br

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  • Ana C. Pero,

    1. Department of Dental Materials and Prosthodontics, Araraquara Dental School, Univ Estadual Paulista - UNESP, Araraquara, São Paulo, Brazil
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  • Stella M. M. Ramos,

    1. Laboratoire PMCN – CNRS UMR 5586, Université Lyon 1, Université de Lyon, France
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  • Juliê Marra,

    1. Department of Prosthodontics, Paulista University, UNIP, Goiânia, Goiás, Brazil
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  • André G. Paleari,

    1. Department of Dental Materials and Prosthodontics, Araraquara Dental School, Univ Estadual Paulista - UNESP, Araraquara, São Paulo, Brazil
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  • Larissa S. Rodriguez

    1. Department of Dental Materials and Prosthodontics, Araraquara Dental School, Univ Estadual Paulista - UNESP, Araraquara, São Paulo, Brazil
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Abstract

Objective

To evaluate the antimicrobial activity and surface properties of an acrylic resin containing the biocide polymer poly (2-tert-butylaminoethyl) methacrylate (PTBAEMA).

Background

Several approaches have been proposed to prevent oral infections, including the incorporation of antimicrobial agents to acrylic resins.

Materials and methods

Specimens of an acrylic resin (Lucitone 550) were divided into two groups: 0% (control) and 10% PTBAEMA. Antimicrobial activity was assessed by adherence assay of one of the microorganisms, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Surface topography was characterised by atomic force microscopy and wettability properties determined by contact angle measurements.

Results

Data of viable cells (log (CFU + 1)/ml) for S. aureus (control: 7.9 ± 0.8; 10%: 3.8 ± 3.3) and S. mutans (control: 7.5 ± 0.7; 10%: 5.1 ± 2.7) showed a significant decrease with 10% of PTBAEMA (Mann–Whitney, p < 0.05). For C. albicans (control: 6.6 ± 0.2; 10%: 6.6 ± 0.4), there was no significant difference between control and 10% of PTBAEMA (Kruskal–Wallis, p > 0.05). Incorporating 10% PTBAEMA increased surface roughness and decreased contact angles.

Conclusion

Incorporating 10% PTBAEMA into acrylic resins increases wettability and roughness of acrylic resin surface; and decreases the adhesion of S. mutans and S. aureus on acrylic surface, but did not exhibit antimicrobial effect against C. albicans.

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