Complications after polymethylmethacrylate (PMMA) injections in the face: a literature review

Authors

  • Clarissa C. G. Medeiros,

    1. Oral Medicine Division, São Lucas Hospital - Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil
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  • Karen Cherubini,

    1. Oral Medicine Division, São Lucas Hospital - Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil
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  • Fernanda G. Salum,

    1. Oral Medicine Division, São Lucas Hospital - Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil
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  • Maria Antonia Z. de Figueiredo

    Corresponding author
    1. Oral Medicine Division, São Lucas Hospital - Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil
    • Correspondence to:

      Maria Antonia Zancanaro de Figueiredo, Hospital São Lucas PUCRS, Av. Ipiranga, 6690 – Sala 231 – 2º andar, 90610-000, Porto Alegre, RS, Brazil.

      Tel.:/Fax: +55 51 3320-3254

      E-mail: antonia.figueiredo@pucrs.br

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Abstract

Objective

This article is a review of the several types of complications due to facial fillers containing polymethylmethacrylate (PMMA).

Background

Polymethylmethacrylate facial fillers are used to soften the results of the ageing process and to augment tissue. Although considered safe for the most part by advocates, they have been associated with many adverse reactions such as ecchymosis, haematomas, swelling, itching, erythema, hypertrophic scarring, hypersensitivity, palpable nodules, tissue necrosis, blindness and foreign body granuloma.

Materials and methods

The articles presented in this review are the result of a search and selection of literature from the National Center for Biotechnology Information (NCBI) database, which met the inclusion criteria for the study.

Conclusion

Polymethylmethacrylate is widely used because it is inexpensive, readily accessible and simple to apply. However, some complications are severe and permanent and can be confused with other types of stomatological lesions.

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