Periodontal disease associated with blood glucose levels in urban Koreans aged 50 years and older: the Dong-gu study

Authors

  • Young-Suk Jung,

    1. Department of Periodontology, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, South Korea
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  • Min-Ho Shin,

    Corresponding author
    1. Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea
    • Correspondence to:

      Ok-Su Kim, Department of Periodontology, School of Dentistry, Dental Science Institute, Chonnam National University, 77 YongBong Rho, Buk-gu, Gwangju, 500-757, South Korea.

      Tel.: +82 62 530 5576

      Fax: +82 62 530 5649

      E-mail: periodrk@chonnam.ac.kr

      and

      Min-Ho Shin, Department of Preventive Medicine, Chonnam National University Medical School, 5, Hak1dong, Donggu, Gwangju City, 501-746, South Korea.

      Tel.: +82 62 220 4166

      Fax: +82 62 233 0305

      E-mail: mhshinx@paran.com

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  • Sun-Seog Kweon,

    1. Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea
    2. Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Hwasun, South Korea
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  • Young-Hoon Lee,

    1. Department of Preventive Medicine, Wonkwang University College of Medicine, Iksan, South Korea
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  • Ok-Joon Kim,

    1. Department of Oral Pathology, School of Dentistry, Dental Science Institute, Chonnam National University, Gwangju, South Korea
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  • Young-Joon Kim,

    1. Department of Periodontology, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, South Korea
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  • Hyun-Ju Chung,

    1. Department of Periodontology, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, South Korea
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  • Ok-Su Kim

    Corresponding author
    1. Department of Periodontology, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, South Korea
    • Correspondence to:

      Ok-Su Kim, Department of Periodontology, School of Dentistry, Dental Science Institute, Chonnam National University, 77 YongBong Rho, Buk-gu, Gwangju, 500-757, South Korea.

      Tel.: +82 62 530 5576

      Fax: +82 62 530 5649

      E-mail: periodrk@chonnam.ac.kr

      and

      Min-Ho Shin, Department of Preventive Medicine, Chonnam National University Medical School, 5, Hak1dong, Donggu, Gwangju City, 501-746, South Korea.

      Tel.: +82 62 220 4166

      Fax: +82 62 233 0305

      E-mail: mhshinx@paran.com

    Search for more papers by this author

Abstract

Objective

To investigate the association of periodontal disease and the number of teeth present with the risk of prediabetes and diabetes as well as with blood glucose and HbA1c levels in adult Koreans.

Background

The relationship between periodontal disease and diabetes has not been fully elucidated.

Materials and methods

Cross-sectional data from 5535 participants aged ≥50 years were obtained from 2008 to 2010. Periodontal status was measured as pocket depth (PD), clinical attachment loss (CAL) and bleeding on probing (BOP) recorded. The percentage of sites with a PD ≥4 mm, CAL ≥4 mm (CAL4) and BOP (BOP%) were recorded. Participants were divided into three groups according to PD4, CAL4 and BOP% measurements. Number of teeth present was divided into four groups. Participants were classified as normoglycaemic, prediabetic or diabetic based on HbA1c and fasting glucose levels.

Results

After full adjustment, the highest tertile of CAL4 (OR: 1.47, 95% CI: 1.18–2.02, p < 0.001), PD4 (OR: 1.58, 95% CI: 1.26–1.97, p < 0.001) and BOP% (OR: 1.37, 95% CI: 1.07–1.75, p = 0.012) had significantly increased odds of diabetes. The number of teeth present was inversely related to diabetes (p < 0.001) and prediabetes (p = 0.032) risk. Periodontal disease severity was positively associated with HbA1c and glucose levels. The number of teeth present was positively associated with HbA1c, but not glucose, levels.

Conclusion

Periodontal disease and the number of teeth present are associated with an increased risk of diabetes and increased blood glucose and HbA1c levels in Koreans aged ≥50 years.

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