SEARCH

SEARCH BY CITATION

Keywords:

  • adjuvant therapy;
  • bypassing therapy;
  • haemophilia A;
  • inhibitors;
  • refractory bleeding

Summary

In haemophilia patients with well-established high-titer inhibitors, even seemingly minor acute bleeding episodes or surgical procedures may become refractory to treatment and transform into limb- or life-threatening situations. In the absence of evidence-based treatment guidelines, this article presents 10 cases of difficult to control acute and surgical bleeding and offers consensus opinions regarding their management from a panel of experienced haemophilia treaters.