Haemophilia

© John Wiley & Sons Ltd

Cover image for Haemophilia

May 2002

Volume 8, Issue 3

Pages 159–468

  1. The Management of Haemophilia

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. The Alonso and Magallón memorial (pages 159–160)

      E. C. Rodriguez-Merchan, J. Tusell, M. Moreno and A. Lavandeira

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00595.x

    2. Concentrate safety and efficacy (pages 161–165)

      C. K. KASPER

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00601.x

    3. Conduct of clinical trials in developing countries (pages 166–169)

      C. K. KASPER

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00594.x

    4. Continuous infusion of coagulation factors (pages 170–177)

      A. Batorova and U. Martinowitz

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00635.x

    5. Paediatric care of the child with haemophilia (pages 178–182)

      R. LJUNG

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00631.x

    6. Prophylaxis in developed and in emerging countries (pages 183–188)

      J. TUSELL and R. PÉREZ-BIANCO

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00619.x

    7. The use of haemostatic drugs in haemophilia: desmopressin and antifibrinolytic agents (pages 189–193)

      A. Villar, V. Jimenez-Yuste, M. Quintana and F. Hernandez-Navarro

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00645.x

    8. Orphan drugs: legal aspects, current situation (pages 194–198)

      A. Lavandeira

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00643.x

    9. Haemophilia in the developing world: the Brazilian experience (pages 199–204)

      S. V. Antunes

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00638.x

    10. Haemophilia care in the developing world: benchmarking for excellence (pages 205–210)

      P. ISARANGKURA

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00600.x

    11. Quality management and quality assurance in haemophilia care: a model at the Bonn haemophilia centre (pages 211–216)

      H-H. Brackmann, W. Effenberger, R. Schwaab, L. Hess, P. Hanfland and J. Oldenburg

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00644.x

    12. Linking medicine and economics: health economics and quality of life in haemophilia care (pages 217–220)

      W. Schramm and K. Berger

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00639.x

  2. Product Safety

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Haemophilia 2002: emerging risks of treatment (pages 221–229)

      B. L. EVATT, A. FARRUGIA, A. D. SHAPIRO and J. T. WILDE

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00612.x

    2. Risk of variant Creuzfeldt–Jakob disease from factor concentrates: current perspectives (pages 230–235)

      A. FARRUGIA

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00618.x

    3. Evolving perspectives in product safety for haemophilia (pages 236–243)

      A. FARRUGIA

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00596.x

  3. Laboratory Aspects of Haemophilia Theraphy

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Laboratory aspects of haemophilia therapy (pages 244–249)

      T. W. BARROWCLIFFE, K. MERTENS, F. E. PRESTON and J. INGERSLEV

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00602.x

  4. Genetic Aspects of Haemophilia Theraphy

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Modifier genes in haemophilia: their expansion in the human genome (pages 250–254)

      E. F. TIZZANO, M. CORNET, M. DOMÈNECH and M. BAIGET

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00623.x

  5. Genetic Aspects of Haemophilia Therapy

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Development of gene therapy for blood disorders by gene transfer into haematopoietic stem cells (pages 255–260)

      S. KARLSSON, A. OOKA and N-B. WOODS

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00470.x

  6. Genetic Aspects of Haemophilia Theraphy

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Gene therapy: reality or myth for the global bleeding disorders community? (pages 261–267)

      K. Kelley, I. Verma and G. F. Pierce

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00646.x

    2. Ethical issues in the genetic aspects of haemophilia (pages 268–272)

      F. SHENFIELD

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00605.x

  7. Inhibitors

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Pathophysiology of inhibitors to factor VIII in patients with haemophilia A (pages 273–279)

      S. LACROIX-DESMAZES, N. MISRA, J. BAYRY, C. ARTAUD, B. DRAYTON, S. V. KAVERI and M. D. KAZATCHKINE

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00624.x

    2. Inhibitors: resolving diagnostic and therapeutic dilemmas (pages 280–287)

      D. DIMICHELE

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00626.x

    3. Orthopaedic surgery in haemophilic patients with inhibitors: an overview (pages 288–291)

      I. HVID and E. C. RODRIGUEZ-MERCHAN

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00607.x

  8. von Willebrand Disease

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. von Willebrand disease: still an intriguing disorder in the era of molecular medicine (pages 292–300)

      F. RODEGHIERO

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00611.x

    2. Advances in the therapy of von Willebrand disease (pages 301–307)

      J. BATLLE, M. S. NOYA, P. GIANGRANDE and M. F. LÓPEZ-FERNÁNDEZ

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00622.x

  9. Rare Coagulation Deficiencies

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Rare coagulation deficiencies (pages 308–321)

      F. Peyvandi, S. Duga, S. Akhavan and P. M. Mannucci

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00633.x

  10. Hepatitis C Infection

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. The natural history and antiviral treatment of hepatitis C in haemophilia (pages 322–329)

      C. LEE and G. DUSHEIKO

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00620.x

  11. Reproductive Issues

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Menorrhagia from a haematologist's point of view. Part I: initial evaluation (pages 330–338)

      P. A. Kouides

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00634.x

    2. Menorrhagia from a haematologist's point of view. Part II: management (pages 339–347)

      J. E. SIEGEL and P. A. KOUIDES

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00621.x

    3. Reproductive choices for couples with haemophilia (pages 348–352)

      J. O. O. Oyesiku and C. F. Turner

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00625.x

    4. Sexuality and haemophilia: connections across the life-span (pages 353–359)

      K. L. Parish

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00647.x

  12. Musculoskeletal Aspects of Haemophilia

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Orthopaedic surgery of haemophilia in the 21st century: an overview (pages 360–368)

      E. C. RODRIGUEZ-MERCHAN

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00562.x

    2. The treatment of intra-articular synovitis by the use of chemical and radioactive substances (pages 369–371)

      M. HEIM

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00598.x

    3. Arthroscopic synovectomy: state of the art (pages 372–374)

      J. D. WIEDEL

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00606.x

    4. Intra-articular hyaluronic acid in the treatment of haemophilic chronic arthropathy (pages 375–381)

      F. FERNÁNDEZ-PALAZZI, R. VISO, A. BOADAS, A. RUIZ-SÁEZ, H. CAVIGLIA and N. BLUMENFELD DE BOSCH

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00627.x

    5. Total knee replacement in haemophilia (pages 382–386)

      N. J. GODDARD, E. C. RODRIGUEZ-MERCHAN and J. D. WIEDEL

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00604.x

    6. Total knee arthroplasty in HIV-positive haemophilic patients (pages 387–392)

      E. C. RODRIGUEZ-MERCHAN and J. D. WIEDEL

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00610.x

    7. Haemophilic cysts (pseudotumours) (pages 393–401)

      E. C. RODRIGUEZ-MERCHAN

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00609.x

    8. Haemophilic pseudotumours of the limbs and their percutaneous treatment (pages 402–406)

      H. A. Caviglia, F. FernÁndez-Palazzi and M. S. Gilbert

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00641.x

    9. Orthoses in haemophilia (pages 407–412)

      F. Querol, J. A. Aznar, S. Haya and A. Cid

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00637.x

    10. Current concepts in electrotherapy (pages 413–418)

      T. WATSON

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00613.x

    11. Clinimetric instruments to assess functional health status in patients with haemophilia: a literature review (pages 419–427)

      P. De Kleijn, L. Heijnen and N. L. U. Van Meeteren

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00640.x

    12. Evaluation of outcome of care in patients with haemophilia (pages 428–434)

      K. BEETON

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00599.x

  13. Ethical Issues

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Progress in haemophilic care: ethical issues (pages 435–438)

      E. BERNTORP

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00615.x

    2. Ethics of haemophilia care in the developing world (pages 439–440)

      M. CHANDY

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00597.x

  14. The patient with Haemophilia

    1. Top of page
    2. The Management of Haemophilia
    3. Product Safety
    4. Laboratory Aspects of Haemophilia Theraphy
    5. Genetic Aspects of Haemophilia Theraphy
    6. Genetic Aspects of Haemophilia Therapy
    7. Genetic Aspects of Haemophilia Theraphy
    8. Inhibitors
    9. von Willebrand Disease
    10. Rare Coagulation Deficiencies
    11. Hepatitis C Infection
    12. Reproductive Issues
    13. Musculoskeletal Aspects of Haemophilia
    14. Ethical Issues
    15. The patient with Haemophilia
    1. Patient autonomy: evolution of the doctor–patient relationship (pages 441–446)

      B. STEINHART

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00614.x

    2. Becoming a partner in your healthcare (pages 447–449)

      R. PAPER

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00603.x

    3. The physician–patient relationship: recent developments and changes (pages 450–454)

      T. HellÍn

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00636.x

    4. Access to medical information in Spain (pages 455–460)

      A. GonzÁlez QuinzÁ

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2001.00632.x

    5. The impact of chronic disease on the family (pages 461–465)

      G. Goldstein and G. Kenet

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00642.x

    6. Education and career development (pages 466–468)

      C. S. MÁRQUEZ

      Article first published online: 16 MAY 2002 | DOI: 10.1046/j.1365-2516.2002.00608.x

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