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Figure S1 Percent distribution of women aged 15-44 by contraceptive method: USA, 2006-2008.

Based on data from: Mosher W, Jones J. Use of contraception in the USA: 1982-2008. National Center for Health Statistics. Vital Health Stat 23. 2010;29:1-44.

Table S1 Formulations of currently marketed combined oral contraceptives.

Table S2 Risk of headache associated with COC containing 20 mcg of EE vs COC containing 30-50 mcg EE.

Table S3 Risk of headache leading to discontinuation of COC containing 20 mcg of EE vs COC containing 30-35 mcg of EE.

Table S4 Risk ratio of headache associated with COC use according to type of progestin.

Table S5 Risk ratio of headache leading to discontinuation of COC according to type of progestin.

Table S6 Risk ratio of migraine associated with COC use according to type of progestin.

Table S7 Risk ratio of migraine leading to discontinuation of COC according to type of progestin.

Table S8 Medical Eligibility Criteria (MEC) for Contraceptive Use of progestin-only and Copper-IUD contraceptives (based on US, WHO, and UK MEC).

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