This review article is based upon a chapter to be published in Dodick, D. and Silberstein, S. (ed.) Migraine, Second Edition. The book is to be published by Oxford University Press. Publication of this review article is with support from Oxford University Press.
Migraine Genetics – A Review: Part I
Article first published online: 12 JUL 2013
© 2013 Oxford University Press Headache: The Journal of Head and Face Pain © 2013 American Headache Society
Headache: The Journal of Head and Face Pain
Volume 53, Issue 8, pages 1207–1217, September 2013
How to Cite
Silberstein, S. and Dodick, D. (2013), Migraine Genetics – A Review: Part I. Headache: The Journal of Head and Face Pain, 53: 1207–1217. doi: 10.1111/head.12156
Conflict of Interest: None.
- Issue published online: 10 SEP 2013
- Article first published online: 12 JUL 2013
- Manuscript Accepted: 22 APR 2013
- deoxyribonucleic acid;
- ribonucleic acid;
Significant progress in molecular genetics has advanced our understanding of the genetic basis of migraine. The fundamentals of molecular genetics, and the recent advances in the field, are important for clinicians to understand, as they provide a foundation for critical appraisal of the literature, unprecedented insights into the pathogenesis of the disorder, and reveal promising treatment targets for future drug development. This paper provides a primer of molecular genetics and will be followed by a companion paper on the genetic advances in migraine, the methodology of genome wide association studies, and the potential clinical implications.