The current research has been conducted in full accordance with the World Medical Association Declaration of Helsinki.
Evaluation of periodontal pathogens of the mandibular third molar pericoronitis by using real time PCR
Article first published online: 19 MAY 2014
© 2014 FDI World Dental Federation
International Dental Journal
Volume 64, Issue 4, pages 200–205, August 2014
How to Cite
Sencimen, M., Saygun, I., Gulses, A., Bal, V., Acikel, C. H. and Kubar, A. (2014), Evaluation of periodontal pathogens of the mandibular third molar pericoronitis by using real time PCR. International Dental Journal, 64: 200–205. doi: 10.1111/idj.12109
- Issue published online: 25 JUL 2014
- Article first published online: 19 MAY 2014
- real-time polymerase chain reaction;
- periodontal bacteria
The aim of this study was to investigate the mandibular third molar pericoronitis flora by using real-time polymerase chain reaction (PCR).
Materials and methods
The quantitative values of Aggregatibacter actinomycetemcomitans (Aa), Campylobacter rectus (Cr), Fusobacterium nucleatum (Fn), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) were evaluated in comparison with the healthy third molar flora by using real time PCR.
Aa, Cr, Pg, and Pi were not statistically significant but numerically higher than the pericoronitis group. In contrast to samples from control subjects, statistically significant higher numbers of Tf were detected in samples from pericoronitis patients. The study revealed the strong relation between risk of pericoronitis and the presence of Tf. Individuals who have Tf in their samples present with an almost eight times relative risk of pericoronitis as the individuals with an absence of Tf in their samples.
Tf plays an important role in the development of clinical symptoms related to pericoronitis.