Conflicts of interest: None.
Pharmacology and therapeutics
Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults
Article first published online: 2 APR 2014
© 2014 The International Society of Dermatology
International Journal of Dermatology
Volume 53, Issue 10, pages 1293–1298, October 2014
How to Cite
Kang, H. S., Lee, M. W., Paek, J. O., Yu, H. J. and Kim, J. S. (2014), Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults. International Journal of Dermatology, 53: 1293–1298. doi: 10.1111/ijd.12377
- Issue published online: 15 SEP 2014
- Article first published online: 2 APR 2014
Immunotherapy has been used for many years in the treatment of warts. Diphenylcyclopropenone is frequently used as an immunotherapeutic agent.
A total of 143 patients with 180 cases of warts were included in this study. We divided the patients into two groups: 72 children/adolescents and 71 adults aged 20 and over. We evaluated two types of sensitization reaction, using an erythema and blister index and a pruritus index.
Of the 180 cases of warts, 159 (88.3%) were completely cured: 86 (92.5%) of the 93 cases in children/adolescents and 73 (83.9%) of the 87 cases in adults. The time required for complete cure was 17.72 ± 2.69 weeks in children/adolescents and 22.92 ± 2.59 weeks in adults (P < 0.05).
Diphenylcyclopropenone immunotherapy can be used effectively for both children/adolescents and adults. The time required for complete cure is shorter in children/adolescents than in adults.