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Keywords:

  • Aflatoxin B1;
  • Ames test;
  • cell toxicity;
  • photodegradation products;
  • UPLC-Q-TOF/MS

Summary

A photodegradation study of Aflatoxin B1 (AFB1) on peanut surface was performed under UV irradiation at different UV irradiation intensities. With an initial quantity of 10 ng of AFB1, it can be degraded thoroughly within 80 min under the intensity of 800 μw cm−2. The photodegradation pathway of AFB1 on the peanut surface was proposed. Mutagenesis and cytotoxicity were assessed after exposure to different concentrations of AFB1 and the mixtures of photodegradation products on the peanut surface. The results of the Ames and in vitro cytotoxicity assay, providing clues to the assessment of safety issues of UV method applied in AFB1 decontamination, indicate that photodegradation products on the peanut surface has no toxicity, which can be explained by the differences in the chemical nature of the test compounds before and after UV irradiation.