The present research was planned to determine the traditional practices used by infertile women to become pregnant and their effects on the quality of life. A hospital-based, descriptive and cross-sectional study. Participant Information Forms and SF-36 quality of life scales were applied to 269 women diagnosed as infertile. Some of the infertile women (32.7%) were determined to use a traditional method. The traditional methods used by women included herbal remedies (those edible and drinkable) (87.5%), sitting on the herbal mixtures (8%) and using both practices (4.5%). The SF-36 Mental Health component was determined to be better in infertile women not using traditional practices than those using traditional practices (P < 0.05). Considering the results of the study, health professionals can question women about the traditional practices and guide them about their damages.