Yongping Liang and Jun Wang are co-first authors.
Coexistence of internal carotid artery stenosis with intracranial aneurysm
Article first published online: 26 AUG 2013
© 2013 The Authors. International Journal of Stroke © 2013 World Stroke Organization
International Journal of Stroke
Volume 9, Issue 3, pages 306–307, April 2014
How to Cite
Liang, Y., Wang, J. and Li, B. (2014), Coexistence of internal carotid artery stenosis with intracranial aneurysm. International Journal of Stroke, 9: 306–307. doi: 10.1111/ijs.12096
Conflict of interest: We declare that we have no conflict of interest.
- Issue published online: 17 MAR 2014
- Article first published online: 26 AUG 2013
- Manuscript Accepted: 19 JAN 2013
- Manuscript Received: 25 DEC 2012
- carotid artery stenosis;
- intracranial aneurysm;
- metabolic syndrome;
- tandem pathology
Studies have hypothesized that alterations in haemodynamics and rheological properties in the main vessels like the main stem of the carotid artery or the internal carotid arteries are responsible for the formation of cerebral aneurysms.
The objectives of the current analyses were to collate data that have examined the occurrence of cerebral aneurysm with coexisting internal carotid artery stenosis.
Data sources were collated from detailed PubMed search obtained from 1990 till current. Published literature that deals with the epidemiologic properties as well as prevalence was scanned for data extraction. Publications that reported coexistence of internal carotid artery stenosis with intracranial aneurysm, detected by any modality of imaging, was included in the current study. Spearman's correlation analyses were used to obtain significant information of coexistence of an intracranial aneurysm with an extracranial internal carotid artery stenosis.
The frequency of concurrent extracranial internal carotid artery stenosis and an unruptured cerebral artery aneurysm is not known exactly, but has been estimated to be approximately 4%. The major limitations of the current analyses actually can be retrospectively traced to the lack of detailed analyses in this important area of investigation.
Although low in absolute occurrence, there is a significant correlation of the existence of an intracranial aneurysm with carotid artery stenosis. Thus, if peripheral stenosis is detected by any imaging modality including carotid Ultrasonography scan, we recommend digital subtraction intracranial angiography to detect any potential aneurysm and define its radiologic morphology.