Conflict of interest: None declared.
Endogenous neuroprotection: Hamartin modulates an austere approach to staying alive in a recession
Article first published online: 23 JUL 2013
© 2013 The Authors. International Journal of Stroke © 2013 World Stroke Organization
International Journal of Stroke
Volume 8, Issue 6, pages 449–450, August 2013
How to Cite
Hadley, G., De Luca, G. C., Papadakis, M. and Buchan, A. M. (2013), Endogenous neuroprotection: Hamartin modulates an austere approach to staying alive in a recession. International Journal of Stroke, 8: 449–450. doi: 10.1111/ijs.12130
- Issue published online: 23 JUL 2013
- Article first published online: 23 JUL 2013
- acute stroke therapy;
- ischemic stroke;
- productive autophagy;
Tuberous sclerosis complex 1 (hamartin) is an effective endogenous neuroprotectant. Understanding the endogenous mechanism for neuroprotection mediated by hamartin may afford a novel approach to effective treatment of neurological diseases such as stroke, neurodegenerative diseases, and epilepsy, with possible applications to nonneurological conditions.