Endogenous neuroprotection: Hamartin modulates an austere approach to staying alive in a recession
- Conflict of interest: None declared.
Correspondence: Alastair M. Buchan, Medical Sciences Division, University of Oxford, Level 3 Room 3600, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Tuberous sclerosis complex 1 (hamartin) is an effective endogenous neuroprotectant. Understanding the endogenous mechanism for neuroprotection mediated by hamartin may afford a novel approach to effective treatment of neurological diseases such as stroke, neurodegenerative diseases, and epilepsy, with possible applications to nonneurological conditions.