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  • 1
    Astrup J, Siesjö BK, Symon L. Thresholds in cerebral ischemia – the ischemic penumbra. Stroke 1981; 12:723725.
  • 2
    Shuaib A, Butcher K, Mohammad AA, Saqqur M, Liebeskind DS. Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target. Lancet Neurol 2011; 10:909921.
  • 3
    Wintermark M, Albers GW, Broderick JP et al.; for the Stroke Imaging Research (STIR) and VISTA-Imaging Investigators. Acute Stroke Imaging Research Roadmap II. Stroke 2013; doi: 10.1161/STROKEAHA.113.002015.
  • 4
    Heiss W-D. Ischemic penumbra: evidence from functional imaging in man. J Cereb Blood Flow Metab 2000; 20:12761293.
  • 5
    Lees KR, Bluhmki E, von Kummer R et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010; 375:16951703.
  • 6
    Albers GW, Thijs VN, Wechsler L et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol 2006; 60:508517.
  • 7
    Davis SM, Donnan GA, Parsons MW et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 2008; 7:299309.
  • 8
    Lansberg MG, Straka M, Kemp S et al. MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol 2012; 11:860867.
  • 9
    Ma H, Parsons MW, Christensen S et al. A multicentre, randomized, double blinded, placebo controlled phase 3 study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND). Int J Stroke 2012; 7:7480.
  • 10
    Schellinger PD, Thomalla G, Fiehler J et al. MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients. Stroke 2007; 38:26402645.
  • 11
    Hjort N, Christensen S, Sølling C et al. Ischemic injury detected by diffusion imaging 11 minutes after stroke. Ann Neurol 2005; 58:462465.
  • 12
    Schellinger PD, Bryan RN, Caplan LR et al. Evidence-based guideline: the role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2010; 75:177185.
  • 13
    Lansberg MG, Thijs VN, Bammer R et al. The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion. Stroke 2008; 39:24912496.
  • 14
    Davalos A, Blanco M, Pedraza S et al. The clinical-DWI mismatch: a new diagnostic approach to the brain tissue at risk of infarction. Neurology 2004; 62:21872192.
  • 15
    Lansberg MG, Thijs VN, Hamilton S et al. Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSE. Stroke 2007; 38:18261830.
  • 16
    Parsons MW, Christensen S, McElduff P et al. Pretreatment diffusion- and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis. J Cereb Blood Flow Metab 2010; 30:12141225.
  • 17
    Yoo AJ, Verduzco LA, Schaefer PW et al. MRI-based selection for intra-arterial stroke therapy: value of pretreatment diffusion-weighted imaging lesion volume in selecting patients with acute stroke who will benefit from early recanalization. Stroke 2009; 40:20462054.
  • 18
    Menezes NM, Ay H, Wang Zhu M et al. The real estate factor: quantifying the impact of infarct location on stroke severity. Stroke 2007; 38:194197.
  • 19
    Kranz PG, Eastwood JD. Does diffusion-weighted imaging represent the ischemic core? An evidence-based systematic review. AJNR Am J Neuroradiol 2009; 30:12061212.
  • 20
    Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol 2007; 6:258268.
  • 21
    Chemmanam T, Campbell BC, Christensen S et al. Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch. Neurology 2010; 75:10401047.
  • 22
    Sakamoto Y, Kimura K, Shibazaki K et al. Early ischaemic diffusion lesion reduction in patients treated with intravenous tissue plasminogen activator: infrequent, but significantly associated with recanalization. Int J Stroke 2013; 8:321326.
  • 23
    Labeyrie MA, Turc G, Hess A et al. Diffusion lesion reversal after thrombolysis: a MR correlate of early neurological improvement. Stroke 2012; 43:29862991.
  • 24
    Campbell BCV, Purushotham A, Christensen S et al. The infarct core is well represented by the acute diffusion lesion: sustained reversal is infrequent. J Cereb Blood Flow Metab 2012; 32:5056.
  • 25
    Li F, Liu KF, Silva MD et al. Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: correlation with histopathology. Stroke 2000; 31:946954.
  • 26
    Guadagno JV, Jones PS, Aigbirhio FI et al. Selective neuronal loss in rescued penumbra relates to initial hypoperfusion. Brain 2008; 131:26662678.
  • 27
    Tourdias T, Dousset V, Sibon I et al. Magnetization transfer imaging shows tissue abnormalities in the reversible penumbra. Stroke 2007; 38:31653171.
  • 28
    Purushotham A, Campbell BC, Straka M et al. Apparent diffusion coefficient threshold for delineation of ischemic core. Int J Stroke 2013, doi: 10.1111/ijs.12068.
  • 29
    An H, Ford AL, Vo K, Powers WJ, Lee JM, Lin W. Signal evolution and infarction risk for apparent diffusion coefficient lesions in acute ischemic stroke are both time- and perfusion-dependent. Stroke 2011; 42:12761281.
  • 30
    Straka M, Albers GW, Bammer R. Real-time diffusion-perfusion mismatch analysis in acute stroke. J Magn Reson Imaging 2010; 32:10241037.
  • 31
    Butcher K, Parsons M, Allport L et al. Rapid assessment of perfusion-diffusion mismatch. Stroke 2008; 39:7581.
  • 32
    Jones TH, Morawetz RB, Crowell RM et al. Thresholds of focal cerebral ischemia in awake monkeys. J Neurosurg 1981; 54:773782.
  • 33
    Marchal G, Beaudouin V, Rioux P et al. Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxel-based data analysis. Stroke 1996; 27:599606.
  • 34
    Hakim AM, Evans AC, Berger L et al. The effect of nimodipine on the evolution of human cerebral infarction studied by PET. J Cereb Blood Flow Metab 1989; 9:523534.
  • 35
    Baron JC. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications. Cerebrovasc Dis 2001; 11(Suppl. 1):28.
  • 36
    Christensen S, Mouridsen K, Wu O et al. Comparison of 10 perfusion MRI parameters in 97 sub-6-hour stroke patients using voxel-based receiver operating characteristics analysis. Stroke 2009; 40:20552061.
  • 37
    Zaro-Weber O, Moeller-Hartmann W, Heiss WD, Sobesky J. Maps of time to maximum and time to peak for mismatch definition in clinical stroke studies validated with positron emission tomography. Stroke 2010; 41:28172821.
  • 38
    Nagakane Y, Christensen S, Ogata T et al. Moving beyond a single perfusion threshold to define penumbra: a novel probabilistic mismatch definition. Stroke 2012; 43:15481555.
  • 39
    Olivot JM, Mlynash M, Zaharchuk G et al. Perfusion MRI (Tmax and MTT) correlation with xenon CT cerebral blood flow in stroke patients. Neurology 2009; 72:11401145.
  • 40
    Christensen S, Campbell BCV, Perez de la Ossa N et al. Optimal perfusion thresholds for prediction of tissue destined for infarction in the combined EPITHET and DEFUSE dataset. Stroke 2010; 41:e297.
  • 41
    Olivot JM, Mlynash M, Thijs VN et al. Optimal Tmax threshold for predicting penumbral tissue in acute stroke. Stroke 2009; 40:469475.
  • 42
    Campbell BCV, Christensen S, Tress BM et al. Failure of collateral blood flow is associated with infarct growth in ischemic stroke. J. Cereb Blood Flow and Metab 2013; 33:11681172.
  • 43
    Christensen S, Parsons MW, De Silva DA et al. Optimal mismatch definitions for detecting treatment response in acute stroke. Cerebrovasc Dis 2008; 25(Suppl. 2):33.
  • 44
    Kakuda W, Lansberg MG, Thijs VN et al. Optimal definition for PWI/DWI mismatch in acute ischemic stroke patients. J Cereb Blood Flow Metab 2008; 28:887891.
  • 45
    Warach S, Al-Rawi Y, Furlan AJ et al. Refinement of the magnetic resonance diffusion-perfusion mismatch concept for thrombolytic patient selection: insights from the desmoteplase in acute stroke trials. Stroke 2012; 43:23132318.
  • 46
    Kidwell CS, Wintermark M, De Silva DA et al. Multiparametric MRI and CT models of infarct core and favorable penumbral imaging patterns in acute ischemic stroke. Stroke 2013; 44:7379.
  • 47
    Kidwell CS, Jahan R, Gornbein J et al. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 2013; 368:914923.
  • 48
    Parsons MW, Albers GW. MR RESCUE: is the glass half-full or half-empty? Stroke 2013; 44:20552057.
  • 49
    Campbell BCV, Christensen S, Parsons MW et al. Advanced imaging improves prediction of hemorrhage after stroke thrombolysis. Ann Neurol 2013; 73:510519.
  • 50
    Campbell BCV, Christensen S, Butcher KS et al. Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke. Stroke 2010; 41:8288.
  • 51
    Kim JH, Bang OY, Liebeskind DS et al. Impact of baseline tissue status (diffusion-weighted imaging lesion) versus perfusion status (severity of hypoperfusion) on hemorrhagic transformation. Stroke 2010; 41:e135142.
  • 52
    Mlynash M, Lansberg MG, De Silva DA et al. Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set. Stroke 2011; 42:12701275.
  • 53
    Planas AM. Noninvasive brain imaging in small animal stroke models: MRI and PET; in Dirnagl U (ed.): Rodent Models of Stroke. Springer Protocols Neuromethods 47. New York, Humana Press, 2010:139165.
  • 54
    Traystman RJ. Effect of anaesthesia in stroke models; in Dirnagl U (ed.): Rodent Models of Stroke. Springer Protocols Neuromethods 47. New York, Humana Press, 2010:121138.
  • 55
    Bulloch R, McCulloch J, Graham DI, Lowe D, Chen MH, Teasdale GM. Focal ischemia in the cat: pre-treatment with a competitive NMDA receptor antagonist, D-CPP-ene. J Cereb Blood Flow Metab 1990; 10:668674.
  • 56
    Imai H, Konno K, Nakamura M et al. A new model of focal cerebral ischaemia in the miniature pig. J Neurosurg 2006; 104:123132.
  • 57
    Yonas H, Wolfson SK, Dujovny M, Boehnke M, Cook E. Selective lenticulostriate occlusion in the primate. A highly focal cerebral ischemia model. Stroke 1981; 12:567572.
  • 58
    Hesselbarth D, Franke C, Hata R, Brinker G, Hoehn-Berlage M. High resolution MRI and MRS: a feasibility study for the investigation of focal cerebral ischemia in mice. NMR Biomed 1998; 11:423429.
  • 59
    Paul R, Zhang ZG, Eliceiri BP et al. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke. Nat Med 2001; 7:222227.
  • 60
    Hughes PM, Allegrini PR, Rudin M, Perry VH, Mir AK, Wiessner C. Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model. J Cereb Blood Flow Metab 2002; 22:308317.
  • 61
    Anderson SA, Frank JA. MRI of mouse models of neurological disorders. NMR Biomed 2007; 20:200215.
  • 62
    Hoehn-Berlage M, Hossmann KA, Busch E, Eis M, Schmitz B, Gyngell ML. Inhibition of nonselective cation channels reduces focal ischemic injury of rat brain. J Cereb Blood Flow Metab 1997; 17:534542.
  • 63
    Li F, Han S, Tatlisumak T et al. A new method to improve in-bore middle cerebral artery occlusion in rats: demonstration with diffusion- and perfusion-weighted imaging. Stroke 1998; 29:17151720.
  • 64
    Hoehn-Berlage M, Norris DG, Kohno K, Mies G, Leibfritz D, Hossmann K-A. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbance. J Cereb Blood Flow Metab 1995; 5:10021011.
  • 65
    Lo EH, Pierce AR, Mandeville JB, Rosen BR. Neuroprotection with NBQX in rat focal cerebral ischemia. Effects on ADC probability distribution functions and diffusion–perfusion relationships. Stroke 1997; 28:439447.
  • 66
    Li F, Carano RAD, Irie K, Sotak CH, Fisher M. Temporal evolution of average apparent diffusion coefficient threshold to define ischemic abnormalities in a rat permanent occlusion model. J Stroke Cerebrovasc Dis 2000; 9:17.
  • 67
    Shen Q, Meng X, Fisher M, Sotak CH, Duong TQ. Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging. J Cereb Blood Flow Metab 2003; 23:14791488.
  • 68
    Meng X, Fisher M, Shen Q, Sotak CH, Duong TQ. Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia. Ann Neurol 2004; 55:207212.
  • 69
    Reid E, Graham D, Lopez-Gonzalez MR, Holmes WM, Macrae IM, McCabe C. Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without co-morbidity: comparison of methods. J Cereb Blood Flow Metab 2012; 32:17651777.
  • 70
    Foley LM, Hitchens TK, Barbe B et al. Quantitative temporal profiles of penumbra and infarction during permanent middle cerebral artery occlusion in rats. Transl Stroke Res 2010; 1:220229.
  • 71
    Letourneur A, Roussel S, Toutain J, Bernaudin M, Touzani O. Impact of genetic and renovascular chronic arterial hypertension on the acute spatiotemporal evolution of the ischemic penumbra: a sequential study with MRI in the rat. J Cereb Blood Flow Metab 2011; 31:504513.
  • 72
    Bardutzky J, Shen Q, Henninger N, Bouley J, Duong TQ, Fisher M. Differences in ischemic lesion evolution in different rat strains using diffusion and perfusion imaging. Stroke 2005; 36:20002005.
  • 73
    Robertson C, McCabe C, Gallagher L et al. Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography. J Cereb Blood Flow Metab 2011; 31:17781787.
  • 74
    Robertson C, McCabe C, Gallagher L et al. Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. J Cereb Blood Flow Metab 2011; 31:17881798.
  • 75
    Bråtane BT, Bouley J, Schneider A, Bastan B, Henninger N, Fisher M. Granulocyte-colony stimulating factor delays PWI/DWI mismatch evolution and reduces final infarct volume in permanent-suture and embolic focal cerebral ischemia models in the rat. Stroke 2009; 40:31023106.
  • 76
    Bråtane BT, Cui H, Cook DJ, Bouley J, Tymianski M, Fisher M. Neuroprotection by freezing ischemic penumbra evolution without cerebral blood flow augmentation with a postsynaptic density-95 protein inhibitor. Stroke 2011; 42:32653270.
  • 77
    McCabe C, Gallagher L, Gsell W, Graham D, Dominiczak AF, Macrae IM. Differences in the evolution of the ischaemic penumbra in the SHRSP and WKY rat. Stroke 2009; 40:38643868.