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Supplementary Material 1. Web registration system of the CRCS-5 registry.

Supplementary Material 2. Definitions in data collection process.

Supplementary Material 3. Case report form of the CRCS-5 registry.

Supplementary Material 4. Immediate response to recanalization treatment.

Supplementary Material 5. Details of surgical treatment.

Supplementary Material 6. Distribution of mRS score at the time of discharge.

Supplementary Material 7. Differences in stroke characteristics, etiologic work-ups, and management among CRCS-5 participating centers.

Supplementary Material 8. Review of previous major stroke registries.

References for the Supporting information.

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