The copyright line of this article has been changed on 02 June 2014, since its first online publication.
Translation of the ‘time is brain’ concept into clinical practice: focus on prehospital stroke management
Article first published online: 4 MAR 2014
© 2014 The Authors. International Journal of Stroke published by John Wiley & Sons Ltd on behalf of World Stroke Organization.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
International Journal of Stroke
Volume 9, Issue 3, pages 333–340, April 2014
How to Cite
Ragoschke-Schumm, A., Walter, S., Haass, A., Balucani, C., Lesmeister, M., Nasreldein, A., Sarlon, L., Bachhuber, A., Licina, T., Grunwald, I. Q. and Fassbender, K. (2014), Translation of the ‘time is brain’ concept into clinical practice: focus on prehospital stroke management. International Journal of Stroke, 9: 333–340. doi: 10.1111/ijs.12252
Conflict of interest: None declared.
- Issue published online: 17 MAR 2014
- Article first published online: 4 MAR 2014
- Manuscript Accepted: 4 DEC 2013
- Manuscript Received: 17 SEP 2013
- emergency medical service;
- mobile stroke unit;
- prehospital phase;
- stroke management;
Acute stroke is one of the main causes of death and chronic disability. Thrombolysis with recombinant tissue plasminogen activator within the first hours after onset of symptoms is an effective therapeutic option for ischemic stroke. However, fewer than 2% to 7% of patients receive this treatment, primarily because most patients reach the hospital too late for the initiation of successful therapy. Several measures can reduce detrimental delay until treatment. It is of importance to use continual public awareness campaigns to reduce delays in patients' alarm of emergency medical services. Further relevant measures are repetitive education of emergency medical services teams to ensure the systematic use of scales designed for recognition of stroke symptoms and the proper triage of patients to stroke centers. A most important time-saving measure is prenotification of the receiving hospital by the emergency medical services team. In the future, treatment already at the emergency site may allow more than a small minority of patients to benefit from available treatment.