• 1
    Jauch EC, Saver JL, Adams HP Jr et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2013; 44:870947.
  • 2
    National Institute of Neurological Disorders and Stroke. Guidelines. The Brain Attack Coalition web site. Available at (accessed 20 October 2013).
  • 3
    The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333:15811588.
  • 4
    Lindsay MP, Gubitz G, Bayley M, Phillips S, on behalf of the Canadian Stroke Best Practices and Standards Working Group (eds). Canadian Best Practice Recommendations for Stroke Care, 4th edn. Ottawa, ON, Canadian Stroke Network, 2013.
  • 5
    National Stroke Foundation. Clinical Guidelines for Stroke Management. Melbourne, 2010. ISBN0-978-0-9805933-3-4.
  • 6
    European Stroke Organisation (ESO) Executive Committee; ESO Writing Committee. Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. Cerebrovasc Dis 2008; 25:457507. doi: 10.1159/000131083; [Epub 6 May 2008].
  • 7
    Wahlgren N, Ahmed N, Davalos A et al. Thrombolysis with alteplase for acute ischaemic stroke in the safe implementation of thrombolysis in stroke-monitoring study (SITS-MOST): an observational study. Lancet 2007; 369:275282.
  • 8
    Hacke W, Kaste M, Fieschi C et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European Cooperative Acute Stroke Study (ECASS). JAMA 1995; 274:10171025.
  • 9
    Yamaguchi T, Mori E, Minematsu K et al. Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT). Stroke 2006; 37:18101815.
  • 10
    Suwanwela NC, Phanthumchinda K, Likitjaroen Y. Thrombolytic therapy in acute ischemic stroke in Asia: the first prospective evaluation. Clin Neurol Neurosurg 2006; 108:549552.
  • 11
    Minematsu K, Toyoda K, Hirano T et al. Guidelines for the intravenous application of recombinant tissue-type plasminogen activator (alteplase), the second edition, October 2012: a guideline from the Japan Stroke Society. J Stroke Cerebrovasc Dis 2013; 22:571600.
  • 12
    The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke: the NINDS t-PA stroke study group. Stroke 1997; 28:21092118.
  • 13
    Derex L, Hermier M, Adeleine P et al. Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator. J Neurol Neurosurg Psychiatry 2005; 76:7075.
  • 14
    Dharmasaroja PA, Muengtaweepongsa S, Pattaraarchachai J, Dharmasaroja P. Intracerebral hemorrhage following intravenous thrombolysis in Thai patients with acute ischemic stroke. J Clin Neurosci 2012; 19:799803.
  • 15
    Ertl-Wagner B, Brandt T, Seifart C, Forsting M. Diagnostic and therapeutic consequences of repeat brain imaging and follow-up vascular imaging in stroke patients. AJNR Am J Neuroradiol 1999; 20:3742.
  • 16
    Schneider LB, Libman RB, Kanner R. Utility of repeat brain imaging in stroke. AJNR Am J Neuroradiol 1996; 17:12591263.
  • 17
    Zahuranec DB, Sanchez BN, Brown DL et al. Computed tomography findings for intracerebral hemorrhage have little incremental impact on post-stroke mortality prediction model performance. Cerebrovasc Dis 2012; 34:8692.
  • 18
    Paliwal PR, Ahmad A, Shen L et al. Persistence of hyperdense middle cerebral artery sign on follow-up CT scan after intravenous thrombolysis is associated with poor outcome. Cerebrovasc Dis 2012; 33:446452.
  • 19
    Dharmasaroja PA, Muengtaweepongsa S, Dharmasaroja P. Post rtPA CT brain may not be mandatory in all stroke patients when resources are limited. Clin Neurol Neurosurg 2013; 115:285288.
  • 20
    Siegler JE, Boehme AK, Dorsey AM et al. Comprehensive Stroke Center Registry: advantages, limitations, and lessons learned. Med Student Res J 2013; 1:2129.
  • 21
    Bender R, Lange S. Adjusting for multiple testing – when and how? J Clin Epidemiol 2001; 54:343349.
  • 22
    Lansberg MG, O'Donnell MJ, Khatri P et al. Antithrombotic and thrombolytic therapy for ischemic stroke: antithrombotic therapy and prevention of thrombosis, 9th ed: American college of chest physicians evidence-based clinical practice guidelines. Chest 2012; 141:e601S636.
  • 23
    Brott T, Broderick J, Kothari R et al. Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke 1997; 28:15.
  • 24
    Kimura K, Iguchi Y, Shibazaki K, Aoki J, Terasawa Y. Hemorrhagic transformation of ischemic brain tissue after t-PA thrombolysis as detected by MRI may be asymptomatic, but impair neurological recovery. J Neurol Sci 2008; 272:136142.
  • 25
    Kablau M, Kreisel SH, Sauer T et al. Predictors and early outcome of hemorrhagic transformation after acute ischemic stroke. Cerebrovasc Dis 2011; 32:334341.