Original Article: Clinical Investigation
Epithelioid angiomyolipoma of the kidney: Radiological imaging
Article first published online: 31 MAR 2013
© 2013 The Japanese Urological Association
International Journal of Urology
Volume 20, Issue 11, pages 1105–1111, November 2013
How to Cite
Tsukada, J., Jinzaki, M., Yao, M., Nagashima, Y., Mikami, S., Yashiro, H., Nozaki, M., Mizuno, R., Oya, M. and Kuribayashi, S. (2013), Epithelioid angiomyolipoma of the kidney: Radiological imaging. International Journal of Urology, 20: 1105–1111. doi: 10.1111/iju.12117
- Issue published online: 29 OCT 2013
- Article first published online: 31 MAR 2013
- Manuscript Accepted: 17 JAN 2013
- Manuscript Received: 3 OCT 2012
- computed tomography;
- magnetic resonance imaging;
- renal cell carcinoma;
- renal neoplasms
To review the imaging findings of renal epithelioid angiomyolipomas.
Eight patients treated at two institutions were pathologically diagnosed as having epithelioid angiomyolipoma. All of them underwent computed tomography, and four underwent magnetic resonance imaging. The tumor size, existence of fat, heterogeneity, computed tomography attenuation, degree of enhancement, enhancement pattern and magnetic resonance imaging signal intensity were evaluated.
Intratumoral fat was not detected in any of the cases. On unenhanced computed tomography, the intratumoral attenuation was hyperattenuating in six of the seven patients who were examined using this modality. On T2-weighted images, the signal intensity of the solid component, cyst wall or septum was low in three of the four cases. Four of the eight cases were heterogeneous solid-type accompanied by hemorrhage, necrosis or hyalinization. One homogeneous solid-type lesion was large in size and was pathologically accompanied by neither hemorrhage nor necrosis. All three multilocular cystic types were pathologically accompanied by massive hemorrhage in the cystic component. One was accompanied by spontaneous perirenal hematoma.
The radiological appearance of most epithelioid angiomyolipomas has a tendency to be hyperattenuating on unenhanced computed tomography images, with low intensities on T2-weighted images. They can be heterogeneously solid, homogeneously solid or a multilocular cystic lesion with massive hemorrhage.