Marantic endocarditis presenting with multifocal neurological symptoms


  • Funding: TJ is funded through a Victorian cancer agency fellowship.
  • Conflict of interest: None.


Thomas John, 145 Studley Road, Heidelberg, Vic. 3084, Australia.



Non-bacterial thrombotic endocarditis (NBTE), also known as marantic endocarditis, has been reported to occur in 0.3–9.3% of the adult population at autopsy. NBTE associated with malignancy is an underrecognised cause of thromboembolic disorders. The clinical spectrum encountered and investigation results can be non-specific, often mimicking other acute conditions such as infective endocarditis. We describe the case of a 34-year-old woman with non-localising and multifocal neurological symptoms, who was subsequently diagnosed with NBTE secondary to a resectable primary lung adenocarcinoma.