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imm12000-sup-0001-FigureS1.tifimage/tif1988KFigure S1. T-cell receptor (TCR) derived from isolated T-cell clones Aa2.2 and Bb5.14 are expressed after genetic transfer into allogeneic effector T cells and show no sign of T cell fratricide.
imm12000-sup-0002-FigureS2.tifimage/tif782KFigure S2. Diverse T-cell receptor (TCR) -transduced effector populations mediate specific cytotoxicity modulated by Toll-like receptor ligand treatment.
imm12000-sup-0003-FigureS3.tifimage/tif2207KFigure S3. B cells have a stimulating effect on proliferation of effector cells transduced with both T-cell receptor (TCR).
imm12000-sup-0004-FigureS4.tifimage/tif1766KFigure S4. Cytokines secreted by T-cell receptor (TCR) -transduced effector T cells reveal a mixed T helper lineage pattern which is dependent on the TCR as well as the target cell.
imm12000-sup-0005-FigureS5.tifimage/tif1262KFigure S5. Opposite effects induced by Toll-like receptor (TLR) ligand treatment of target B cells are associated to characteristics of the transgenic T-cell receptor (TCR) additionally demonstrated by transduction of allogeneic effector cells.
imm12000-sup-0006-FigureS6.tifimage/tif677KFigure S6. Toll-like receptor (TLR) treatment of T-cell receptor (TCR) -transduced effector cells has no effect on functionality of transduced autologous T cells.
imm12000-sup-0007-FigureS7.tifimage/tif613KFigure S7. Toll-like receptor (TLR) ligand treatment of C1R cells transfected with selected HLA restriction elements mediates opposite effects on cytokine secretion by T-cell receptor (TCR) -transduced effector populations.
imm12000-sup-0008-TableS1.pdfapplication/PDF180KTable S1. Cytokine Response of Aa2.2 and Bb5.14 transduced effector cells in response to (A) chronic lymphatic leukaemia (CLL), (B) acute myeloid leukaemia (AML) and (C) non-haematopoietic cell lines.
imm12000-sup-0009-TableS2.pdfapplication/PDF167KTable S2. Immune modulation of T-cell receptor (TCR) -transduced T cells by Toll-like receptor (TLR) -ligand treated B cells.
imm12000-sup-0010-SupplementFigurelegends.pdfapplication/PDF137K 

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