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Figure S1. Weekly vital statistics (NCHS) mortality time series and model predictions for pneumonia and influenza (P&I) in (A) under 5-year-olds, (B) 5- to-24-year-olds, (C) 25- to-44-year-olds, (D) 45- to-64-year-olds, and (E) Over 65 years.

Figure S2. Same as Figure S1 but for respiratory causes.

Figure S3. Same as Figure S1 but for respiratory and cardiac (R&C) causes.

Figure S4. Weekly inpatient mortality rates due to pneumonia and influenza in (A) under 5-year-olds, (B) 5- to-24-year-olds, (C) 25- to-44-year-olds, (D) 45- to-64-year-olds, and (E) over 65 years, 2003/04–2009/10 seasons.

Figure S5. Same as Figure S4, but for respiratory and cardiac causes (R&C).

Table S1. Diagnostic codes used to extract deaths due to pneumonia and influenza (P&I), respiratory causes, and respiratory and cardiac causes (R&C) in inpatient records and vital statistics data.

Table S2. Proportion of cause- and age-specific US deaths captured by the State Inpatient Databases system for two mortality outcomes listed anywhere on the hospitalization record: Pneumonia and Influenza (P&I) and respiratory causes.

Table S3. Age-specific excess mortality rates due to pneumonia and influenza (P&I), respiratory causes, and respiratory and cardiac causes, derived from NCHS vital statistics data.

Table S4. Age distribution of excess deaths during the pandemic and historical seasons from the NCHS and SID datasets.

Table S5. Number of influenza-related excess deaths and years of life lost (YLL) derived from respiratory and cardiac mortality in vital statistics data (NCHS) for select historical years and the truncated pandemic period (Apr–Dec 2009).

Table S6. Spearman's and Pearson's correlation coefficients between weekly time series of vital statistics (multiple causes) and inpatient mortality (underlying and multiple causes) for three disease outcomes, 1990–2008.

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