Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes
Article first published online: 10 NOV 2013
© 2013 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
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Influenza and Other Respiratory Viruses
Volume 8, Issue 1, pages 21–24, January 2014
How to Cite
2014) Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes. Influenza and Other Respiratory Viruses 8(1), 21–24.et al. (
- Issue published online: 20 DEC 2013
- Article first published online: 10 NOV 2013
- Manuscript Accepted: 19 SEP 2013
- Japan Initiative for Global research Network on Infectious Diseases (J-GRID)
- Ministry of Education, Culture, Sports, Science and Technology (MEXT)
- Japan, Science and Technology Research Partnership for Sustainable Development (SATREPS)
- Japan Science and Technology Agency (JST)
- Japan International Cooperation Agency (JICA)
- Japan Society for the Promotion of Science (JSPS)
- Enterovirus 68;
- pediatric pneumonia;
Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.