irv12219-sup-0001-FigS1.tifimage/tif667KFigure S1. HA Variability among Ontario's influenza A (H3N2) virus during 2010–2011 Influenza season.
irv12219-sup-0002-FigS2.tifimage/tif461KFigure S2. Amino acid sequence alignment of A/Ontario/C706264/2010(H3N2) to MDCK grown A/Perth/16/2009 (Genbank accession # GQ293081.1).
irv12219-sup-0003-Figure-Legends.docxWord document14K 
irv12219-sup-0004-TabS1-S2.docxWord document21K

Table S1. Parameter estimates, dN/dS, values of log-Likelihood (l), positive selection sites, and Likelihood Ratio Tests (LRT) in the Hemagglutinin gene analysis of influenza A H3N2 viruses circulating in Ontario, Canada between November 2010 and February 2011.

Table S2. Comparative analysis of ON H3N2 HA mutational patterns at antigenic sites with other geographical regions.

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