Accelerated Hazards Regression Model and Its Adequacy for Censored Survival Data
Article first published online: 21 MAY 2004
Volume 57, Issue 3, pages 853–860, September 2001
How to Cite
Qing Chen, Y. (2001), Accelerated Hazards Regression Model and Its Adequacy for Censored Survival Data. Biometrics, 57: 853–860. doi: 10.1111/j.0006-341X.2001.00853.x
- Issue published online: 21 MAY 2004
- Article first published online: 21 MAY 2004
- Received July 2000. Revised February 2001. Accepted March 2001.
- Accelerated hazards;
- Scale change;
- Survival data
Summary. The accelerated hazards regression model is introduced to study the relationship between survival times and covariates through a scale change between hazard functions. The model is also compared with several other popular classes of regression models for censored survival data in statistical literature. Test statistics are proposed and studied to assess the model's adequacy. Actual data from a randomized clinical trial of biodegradable carmustine polymer for treatment of brain cancer are analyzed to demonstrate the potential application of the regression model and the proposed test statistics.