Design Considerations for Efficient and Effective Microarray Studies
Version of Record online: 11 DEC 2003
Volume 59, Issue 4, pages 822–828, December 2003
How to Cite
Kathleen Kerr, M. (2003), Design Considerations for Efficient and Effective Microarray Studies. Biometrics, 59: 822–828. doi: 10.1111/j.0006-341X.2003.00096.x
- Issue online: 11 DEC 2003
- Version of Record online: 11 DEC 2003
- Received September 2002. Revised June 2003. Accepted July 2003.
- Block design;
- Composite sampling;
- Experimental design;
- Gene expression;
Summary. This article describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this article 1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and 2) provides some general guidelines for statisticians designing microarray studies.