Innate and adaptive immunity: the Yin and Yang of celiac disease
Article first published online: 28 JUL 2005
Volume 206, Issue 1, pages 219–231, August 2005
How to Cite
Jabri, B., Kasarda, D. D. and Green, P. H. R. (2005), Innate and adaptive immunity: the Yin and Yang of celiac disease. Immunological Reviews, 206: 219–231. doi: 10.1111/j.0105-2896.2005.00294.x
- Issue published online: 28 JUL 2005
- Article first published online: 28 JUL 2005
Summary: Celiac disease is a multigenetic complex inflammatory disorder with an autoimmune component, induced by gluten, a protein found in wheat. It is a unique human disease model to dissect the innate and adaptive immune mechanisms underlying T-cell-mediated tissue destruction and the development of T-cell lymphoma in conditions of chronic T-cell activation.