• 1
    Adult Treatment Panel III. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. JAMA. 2001;285:24862497.
  • 2
    Hunt ME, O'Malley PG, Feuerstein I, et al. The relationship between the ‘metabolic score’ and sub-clinical atherosclerosis detected with electron beam computed tomography. Coron Artery Dis. 2003;14:317322.
  • 3
    Ford ES, Giles WH, Dietz WH. Prevalence of metabolic syndrome among adults. JAMA. 2002;287:356359.
  • 4
    Lakka HM, Laaksonen DE, Lakka TA. et al. The metabolic syndrome and total cardiovascular disease mortality in middle-aged men. JAMA. 2002;288:27092716.
  • 5
    Klein BE, Klein R, Lee KE. Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in beaver dam. Diabetes Care. 2002;25:17901794.
  • 6
    Ninomiya JK, L'Italien G, Criqui MH, et al. Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation. 2004;109:4246.
  • 7
    Deedwania PC. Metabolic syndrome and vascular disease: is nature or nurture leading the new epidemic of cardiovascular disease? Circulation. 2004;109:24.
  • 8
    Malik S, Wong ND, Franklin SS. et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 2004;110:12451250.
  • 9
    Hu G, Qiao Q, Tuomilehto J. et al., for the DECODE Study Group. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med. 2004;164:10661076.
  • 10
    Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care. 2004;27:24442449.
  • 11
    Torjesen PA, Birkeland KI, Anderssen SA. et al. Lifestyle changes may reverse development of the insulin resistance syndrome: the Oslo Diet and Exercise Study: a randomized trial. Diabetes Care. 1997;20:2631.
  • 12
    Watkins LL, Sherwood A, Feinglos M. et al. Effects of exercise and weight loss on cardiac risk factors associated with syndrome X. Arch Intern Med. 2003;163:18891895.
  • 13
    Anderssen SA, Hjermann I, Urdal P. et al. Improved carbohydrate metabolism after physical training and dietary intervention in individuals with the ‘atherothrombogenic syndrome’. Oslo Diet and Exercise Study (ODES). A randomized trial. J Intern Med. 1996;240:203209.
  • 14
    Castaneda C, Layne JE, Munoz-Orians L, et al. A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes Care. 2002;25:23352341.
  • 15
    Kang HS, Gutin B, Barbeau P. et al. Physical training improves insulin resistance syndrome markers in obese adolescents. Med Sci Sports Exerc. 2002;34:19201927.
  • 16
    McAuley KA, Williams SM, Mann JI. et al. Intensive lifestyle changes are necessary to improve insulin sensitivity: a randomized controlled trial. Diabetes Care. 2002;25:445452.
  • 17
    Knowler WC, Barrett-Connor E, Fowler SE, et al. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393403.
  • 18
    O'Malley PG, Feuerstein IM, Taylor AJ. Impact of electron beam tomography, with or without case management, on motivation, behavioral change, and cardiovascular risk profile: a randomized controlled trial. JAMA. 2003;289:22152223.
  • 19
    Moher D, Schulz KF, Altman D. for the CONSORT Group. The CONSORT Statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA. 2001;285:19871991.
  • 20
    O'Malley PG, Taylor A, Gibbons RV, et al. Rationale and design of the Prospective Army Coronary Calcium (PACC) study: the utility of EBCT as a screening test for coronary artery disease, and as an intervention for risk factor modification among over 40 active duty personnel. Am Heart J. 1999;137:932941.
  • 21
    Taylor AJ, Wong H, Wish K. et al. Validation of the MEDFICTS dietary questionnaire: a clinical tool to assess adherence to American Heart Association dietary fat intake guidelines. Nutr J. 2003;2:4.
  • 22
    Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999;282:17371744.
  • 23
    Taylor AJ, Watkins T, Bell D. Physical activity and the presence and extent of calcified coronary atherosclerosis. Med Sci Sports Exerc. 2002;34:228233.
  • 24
    DiClemente CC, Prochaska JO, Fairhurst SK. The process of smoking cessation: an analysis of the precontemplation, contemplation, and preparation stages of change. J Consult Clin Psychol. 1991;59:295304.
  • 25
    Biener L, Abrams DB. The contemplation ladder: validation of a measure of readiness to consider smoking cessation. Health Psychol. 1991;10:360365.
  • 26
    Lichtman JH, Amatruda J, Yaari S. et al. Clinical trial of an educational intervention to achieve recommended cholesterol levels in patients with coronary artery disease. Am Heart J. 2004;147:522528.
  • 27
    Stefanick ML, Mackey S, Sheehan M. et al. Effects of diet and exercise in men and post-menopausal women with low levels of HDL cholesterol and high levels of LDL cholesterol. N Engl J Med. 1998;339:1220.
  • 28
    Lindstrom J, Louheranta A, Mannelin M. et al., for the Finnish Diabetes Prevention Study Group. The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care. 2003;26:32303236.
  • 29
    DeBusk RF, Miller NH, Superko HR, et al. A case-management system for coronary risk factor modification after acute myocardial infarction. Ann Intern Med. 1994;120:721729.
  • 30
    Haskell WL, Alderman EL, Fair JM. et al. Effects of intensive multiple risk factor reduction on coronary atherosclerosis and clinical cardiac events in men and women with coronary artery disease. The Stanford Coronary Risk Intervention Project (SCRIP). Circulation. 1994;89:975990.
  • 31
    Gordon NF, English CD, Contractor AS, et al. Effectiveness of three models for comprehensive cardiovascular disease risk reduction. Am J Cardiol. 2002;89:12631268.
  • 32
    The Multipl. Risk Factor Intervention Trial Research Group. Mortality rates after 10.5 years for participants in the Multiple Risk Factor Intervention Trial. Findings related to a priori hypotheses of the trial. JAMA. 1990;263:17951801.
  • 33
    Katzel LI, Bleecker ER, Colman EG. et al. Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. A randomized controlled trial. JAMA. 1995;274:19151921.
  • 34
    Appel LJ, Champagne CM, Harsha DW. et al. Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. JAMA. 2003;289:20832093.
  • 35
    Gump BB, Matthews KA. Special intervention reduces CVD mortality for adherent participants in the multiple risk factor intervention trial. Ann Behav Med. 2003;26:6168.
  • 36
    Killen JD, Telch MJ, Robinson TN. et al. Cardiovascular disease risk reduction for tenth graders. A multi-factor school-based approach. JAMA. 1988;260:17281733.
  • 37
    Harrell JS, Gansky SA, McMurray RG. et al. School-based interventions improve heart health in children with multiple cardiovascular disease risk factors. Pediatrics. 1998;102:371380.
  • 38
    Meland E, Maeland JG, Laerum E. The importance of self-efficacy in cardiovascular risk factor change. Scand J Public Health. 1999;27:1117.
  • 39
    Daviglus ML, Liu K, Pirzada A. et al. Cardiovascular risk profile earlier in life and Medicare costs in the last year of life. Arch Intern Med. 2005;165:10281034.
  • 40
    Cutler JA, Grandits GA, Grimm RH. et al. Risk factor changes after cessation of intervention in the Multiple Risk Factor Intervention Trial. Prev Med. 1991;20:183196.
  • 41
    Hung HC, Joshipura KJ, Jiang R. et al. Fruit and vegentake and risk of major chronic diseaseTable I. J Natl Cancer Inst. 2004;96:15771584.
  • 42
    Sexton M, Bross D, Hebel JR. et al. Risk-factor changes in wives with husbands at high risk of coronary heart disease (CHD): the spin-off effect. J Behav Med. 1987;10:251261.
  • 43
    Ketola E, Makela M, Klockars M. Individualized multifactorial lifestyle intervention trial for high risk cardiovascular patients in primary care. Br J Gen Pract. 2001;51:291294.
  • 44
    Johannesson M, Agewall S, Hartford M. et al. The cost-effectiveness of a cardiovascular multiple-risk-factor intervention programme in treated hypertensive men. J Intern Med. 1995;237:1926.