Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques
Article first published online: 5 OCT 2006
Skin Research and Technology
Volume 12, Issue 4, pages 241–246, November 2006
How to Cite
Dal'Belo, S. E., Rigo Gaspar, L. and Berardo Gonçalves Maia Campos, P. M. (2006), Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Research and Technology, 12: 241–246. doi: 10.1111/j.0909-752X.2006.00155.x
- Issue published online: 5 OCT 2006
- Article first published online: 5 OCT 2006
- Accepted for publication 14 July 2005
- Aloe vera extract;
- skin hydration
Background/purpose: The polysaccharide-rich composition of Aloe vera extracts (Aloe barbadensis Miller), often used in cosmetic formulations, may impart moisturizing properties to the product. The aim of this study was to evaluate the effect of cosmetic formulations containing different concentrations of freeze-dried Aloe vera extract on skin hydration, after a single and a 1- and 2-week period of application, by using skin bioengineering techniques.
Methods: Stable formulations containing 5% (w/w) of a trilaureth-4 phosphate-based blend were supplemented with 0.10%, 0.25% or 0.50% (w/w) of freeze-dried Aloe vera extract and applied to the volar forearm of 20 female subjects. Skin conditions in terms of the water content of the stratum corneum and of transepidermal water loss (TEWL) (CorneometerTM CM 825 and TewameterTM TM 210) were analysed before and after a single and 1- and 2-week period of daily application.
Results: After a single application, only formulations supplemented with 0.25% and 0.50% (w/w) of Aloe vera extract increased the water content of the stratum corneum, while after the 2-week period application, all formulations containing the extract (0.10%, 0.25% and 0.50%) had the same effect, in both cases as compared with the vehicle. TEWL was not modified after a single and after 1- and 2-week period of application, when compared with the vehicle.
Conclusion: Our results show that freeze-dried Aloe vera extract is a natural effective ingredient for improving skin hydration, possibly through a humectant mechanism. Consequently, it may be used in moisturizing cosmetic formulations and also as a complement in the treatment of dry skin.