Biochemical Variables Related to Calcium Metabolism in Epileptics
Article first published online: 24 APR 2009
1979 Association for the Publication of the Journal of Internal Medicine
Acta Medica Scandinavica
Volume 205, Issue 1-6, pages 401–404, January/December 1979
How to Cite
Dymling, J. F., Lidgren, L. and Wallöe, A. (1979), Biochemical Variables Related to Calcium Metabolism in Epileptics. Acta Medica Scandinavica, 205: 401–404. doi: 10.1111/j.0954-6820.1979.tb06072.x
- Issue published online: 24 APR 2009
- Article first published online: 24 APR 2009
- anticonvulsant drugs;
- fragility fractures.
ABSTRACT. Five biochemical variables, S-Ca, U- Ca, S-P, U-P and S-ALP, all involved in calcium metabolism, have been investigated in 86 epileptics on long-term medication. We found hypocalciuria in half of the epileptics and increased S-ALP in one third. In contrast to earlier reports there was no hypocalcemia, whereas hypercalcemia was found in 7 epileptics. We have previously reported a high frequency of fractures in these epileptics. An increased fracture rate was found in the 13 epileptics with both hypocalciuria and increased S-ALP, indicating osteomalacia.