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Influence of a Myocardial Infarction on Blood Pressure and Serum Cholesterol

Authors

  • Michael McCall,

    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
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  • Dag Elmfeldt,

    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
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  • Anders Vedin,

    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
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  • Claes Wilhelmsson,

    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
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  • Hans Wedel,

    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
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  • Lars Wilhelmsen M.D

    Corresponding author
    1. the Section of Preventive Cardiology, Department of Medicine I, Sahlgrenska Hospital, Department of Medicine, östra Hospital, Göteborg, Sweden, and Department of Medicine, Perth Medical Centre, Nedlands, Australia
      Department of Medicine, östra Hospital, S-41685 Göteborg, Sweden.
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Department of Medicine, östra Hospital, S-41685 Göteborg, Sweden.

Abstract

ABSTRACT Blood pressure (BP) was measured before and after acute myocardial infarction (MI) in 21 men aged 49–60 years from a random population sample. Men on drugs affecting BP before MI or during follow-up were excluded. Pre- and postinfarction cholesterol levels were analyzed in 49 men not on hyperlipidemic treatment recruited from the same population sample. The mean fall in systolic BP (SBP) was 14 mmHg both five weeks and one year after the acute event, but 10 mmHg after two years. The mean fall in diastolic BP (DBP) was 10 mmHg five weeks after the MI and remained at this level for two years. The decreases in SBP and DBP were significant. There was a positive correlation between the maximum rise in SGOT during the acute phase of MI and the decrease in DBP between preinfarction readings and readings five weeks after the MI. Serum cholesterol was unchanged three months, and one and two years after the MI as compared to the preinfarction level.

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