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- The function of DNA methylation in vertebrates and plants
- DNA methylation in insects
- Drosophila melanogaster: non-CpG methylation mediated by Dnmt2
- Mamestra brassicae: high levels of genome methylation
- Myzus persicae: methylation of amplified esterase genes
- Planococcus citri: DNA methylation and genomic imprinting
Cytosine DNA methylation has been demonstrated in numerous eukaryotic organisms and has been shown to play an important role in human disease. The function of DNA methylation has been studied extensively in vertebrates, but establishing its primary role has proved difficult and controversial. Analysing methylation in insects has indicated an apparent functional diversity that seems to argue against a strict functional conservation. To investigate this hypothesis, we here assess the data reported in four different insect species in which DNA methylation has been analysed more thoroughly: the fruit fly Drosophila melanogaster, the cabbage moth Mamestra brassicae, the peach-potato aphid Myzus persicae and the mealybug Planococcus citri.