Case of localized scleroderma associated with osteomyelitis
Article first published online: 24 JAN 2010
© 2010 Japanese Dermatological Association
The Journal of Dermatology
Special Issue: Systemic Sclerosis (pages 1-84)
Volume 37, Issue 1, pages 81–84, January 2010
How to Cite
MUROI, E., OGAWA, F., YAMAOKA, T., SUEYOSHI, F. and SATO, S. (2010), Case of localized scleroderma associated with osteomyelitis. The Journal of Dermatology, 37: 81–84. doi: 10.1111/j.1346-8138.2009.00751.x
- Issue published online: 24 JAN 2010
- Article first published online: 24 JAN 2010
- Received 16 February 2009; accepted 11 August 2009.
- anti-single-stranded DNA antibody;
- localized scleroderma;
- magnetic resonance image;
We report a 4-year-old girl presenting with progressive linear scleroderma affecting the right leg. Biopsy specimen disclosed typical histopathological findings of localized scleroderma. Right leg magnetic resonance imaging (MRI) showed high signal areas on T2-weighted images on the subcutaneous fatty tissue, muscles and bone marrow, suggesting that skin inflammation extended to the bone marrow. Oral corticosteroid therapy was instituted with improvement of both skin sclerosis and MRI findings. Our observations suggest that MRI examination should be considered in patients with localized scleroderma to evaluate the extension of the inflammation.