Case of livedoid vasculopathy with extensive dermal capillary thrombi
Article first published online: 24 JAN 2010
© 2010 Japanese Dermatological Association
The Journal of Dermatology
Special Issue: Systemic Sclerosis (pages 1-84)
Volume 37, Issue 1, pages 94–97, January 2010
How to Cite
SHIMIZU, A., TAMURA, A., YAMANAKA, M., AMANO, H., NAGAI, Y. and ISHIKAWA, O. (2010), Case of livedoid vasculopathy with extensive dermal capillary thrombi. The Journal of Dermatology, 37: 94–97. doi: 10.1111/j.1346-8138.2009.00753.x
- Issue published online: 24 JAN 2010
- Article first published online: 24 JAN 2010
- Received 16 November 2007; accepted 11 August 2009.
- livedo reticularis;
- livedoid vasculopathy;
- thrombogenic factors
Livedoid vasculopathy (LV) is thought to be a thrombogenic disorder. Here, we report a case of LV presenting livedo reticularis with leg ulcers clinically and many thrombogenic cutaneous vessels histologically. These features strongly suggested the presence of thrombogenic factors involved with the development of the lesions. After examination of various possible thrombogenic factors including phosphatidylserine-dependent anti-prothrombin antibody, we failed to detect any responsible thrombogenic factors for this case of LV. Recently, diverse thrombogenic factors have been reported to be involved in LV. This case may suggest that unknown thrombogenic factors are additionally related to LV pathogenesis.