• 1
    Anagnostopoulos, I., Herbst, H., Niedobitek, G., and Stein, H. 1989. Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization. Blood 74: 810816.
  • 2
    Asada, H., Okada, N., Tei, H., Yamamura, T., Hashimoto, K., Kondo, K., Yamanishi, K., and Yoshikawa, K. 1994. Epstein-Barr virus-associated large granular lymphocyte leukemia with cutaneous infiltration. J. Am. Acad. Dermatol. 31: 251255.
  • 3
    Baichwal, V.R., and Sugden, B. 1988. Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus. Oncogene 2: 461467.
  • 4
    Burke, A.P., Yen, T.S., Shekitka, K.M., and Sobin, L.H. 1990. Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction. Mod. Pathol. 3: 377380.
  • 5
    Chan, J.K. 1999. Peripheral T-cell and NK-cell neoplasms: an integrated approach to diagnosis. Mod. Pathol. 12: 177199.
  • 6
    Chang, K.L., Chen, Y.Y., Shibata, D., and Weiss, L.M. 1992. Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues. Diagn. Mol. Pathol. 1: 246255.
  • 7
    Chiang, A.K., Srivastava, G., Lau, P.W., and Ho, F.C. 1996. Differences in T-cell-receptor gene rearrangement and transcription in nasal lymphomas of natural killer and T-cell types: implications on cellular origin. Hum. Pathol. 27: 701707.
  • 8
    Chiang, A.K., Tao, Q., Srivastava, G., and Ho, F.C. 1996. Nasal NK-and T-cell lymphomas share the same type of Epstein-Barr virus latency as nasopharyngeal carcinoma and Hodgkin's disease. Int. J. Cancer. 68: 285290.
  • 9
    Cho, K.H., Kim, C.W., Lee, D.Y., Sohn, S.J., Kim, D.W., and Chung, J.H. 1996. An Epstein-Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face. Br. J. Dermatol. 134: 791796.
  • 10
    Cleary, M.L., Nalesnik, M.A., Shearer, W.T., and Sklar, J. 1988. Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus. Blood 72: 349352.
  • 11
    Devergne, O., Hatzivassiliou, E., Izumi, K.M., Kaye, K.M., Kleijnen, M.F., Kieff, E., and Mosialos, G. 1996. Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation. Mol. Cell. Biol. 16: 70987108.
  • 12
    Doll, D.C., and List, A.F. 1982. Burkitt's lymphoma in a homosexual. Lancet 1: 10261027.
  • 13
    Epstein, M.A., Achong, B.G., and Barr, Y.M. 1964. Virus particles in cultured lymphocytes from Burkitt's lymphoma. Lancet 1: 702703.
  • 14
    Gires, O., Kohlhuber, F., Kilger, E., Baumann, M., Kieser, A., Kaiser, C., Zeidler, R., Scheffer, B., Ueffing, M., and Hammerschmidt, W. 1999. Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins. EMBO J. 18: 30643073.
  • 15
    Goldgeier, M.H., Nordlund, J.J., Lucky, A.W., Sibrack, L.A., McCarthy, M.J., and McGuire, J. 1982. Hydroa vacciniforme: diagnosis and therapy. Arch. Dermatol. 118: 588591.
  • 16
    Hanto, D.W., Gajl Peczalska, K.J., Frizzera, G., Arthur, D.C., Balfour, H.H. Jr., McClain, K., Simmons, R.L., and Najarian, J.S. 1983. Epstein-Barr virus (EBV) induced polyclonal and monoclonal B-cell lymphoproliferative diseases occurring after renal transplantation. Clinical, pathologic, and virologic findings and implications for therapy. Ann. Surg. 198: 356369.
  • 17
    Harabuchi, Y., Yamanaka, N., Kataura, A., Imai, S., Kinoshita, T., Mizuno, F., and Osato, T. 1990. Epstein-Barr virus in nasal T-cell lymphomas in patients with lethal midline granuloma. Lancet 335: 128130.
  • 18
    Henderson, S., Rowe, M., Gregory, C., Croom Carter, D., Wang, F., Longnecker, R., Kieff, E., and Rickinson, A. 1991. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65: 11071115.
  • 19
    Henle, G., Henle, W., and Diehl, V. 1968. Relation of Burkitt's tumor-associated herpes-type virus to infectious mononucleosis. Proc. Natl. Acad. Sci. U.S.A. 59: 94101.
  • 20
    Ho, F.C., Srivastava, G., Loke, S.L., Fu, K.H., Leung, B.P., Liang, R., and Choy, D. 1990. Presence of Epstein-Barr virus DNA in nasal lymphomas of B and ‘T’ cell type. Hematol. Oncol. 8: 271281.
  • 21
    Imai, S., Sugiura, M., Oikawa, O., Koizumi, S., Hirao, M., Kimura, H., Hayashibara, H., Terai, N., Tsutsumi, H., Oda, T., Chiba, S., and Osato, T. 1996. Epstein-Barr virus (EBV)-carrying and-expressing T-cell lines established from severe chronic active EBV infection. Blood 87: 14461457.
  • 22
    Ishihara, S., Tawa, A., Yumura Yagi, K., Murata, M., Hara, J., Yabuuchi, H., Hirai, K., and Kawa Ha, K. 1989. Clonal T-cell lymphoproliferation containing Epstein-Barr (EB) virus DNA in a patient with chronic active EB virus infection. Jpn. J. Cancer Res. 80: 99101.
  • 23
    Iwatsuki, K., Ohtsuka, M., Harada, H., Han, G., and Kaneko, F. 1997. Clinicopathologic manifestations of Epstein-Barr virus-associated cutaneous lymphoproliferative disorders. Arch. Dermatol. 133: 10811086.
  • 24
    Iwatsuki, K., Xu, Z., Takata, M., Iguchi, M., Ohtsuka, M., Akiba, H., Mitsuhashi, Y., Takenoshita, H., Sugiuchi, R., Tagami, H., and Kaneko, F. 1999. The association of latent Epstein-Barr virus infection with hydroa vacciniforme. Br. J. Dermatol. 140: 715721.
  • 25
    Iwatsuki, K., Ohtsuka, M., Akiba, H., and Kaneko, F. 1999. Atypical hydroa vacciniforme in childhood: from a smoldering stage to Epstein-Barr virus-associated lymphoid malignancy. J. Am. Acad. Dermatol. 40: 283284.
  • 26
    Iwatsuki, K., Xu, Z., Ohtsuka, M., and Kaneko, F. 2000. Cutaneous lymphoproliferative disorders associated with Epstein-Barr virus infection: a clinical overview. J. Dermatol. Sci. 22: 181195.
  • 27
    Jaffe, E.S., Krenacs, L., Kumar, S., Kingma, D.W., and Raffeld, M. 1999. Extranodal peripheral T-cell and NK-cell neoplasms. Am. J. Clin. Pathol. 111: S4655.
  • 28
    Kanno, T., Brown, K., and Siebenlist, U. 1995. Evidence in support of a role for human T-cell leukemia virus type I Tax in activating NF-kappa B via stimulation of signaling pathways. J. Biol. Chem. 270: 1174511748.
  • 29
    Kaye, K.M., Izumi, K.M., and Kieff, E. 1993. Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation. Proc. Natl. Acad. Sci. U.S.A. 90: 91509154.
  • 30
    Kieff, E. 1996. Epstein-Barr virus, p. 23432396. In Fields, B.N., Kinipe, D.M., Howley, P.M. (eds), Virology, 3rd ed., Lippincott-Raven Publishers, Philadelphia.
  • 31
    Kimura, H., Hoshino, Y., Kanegane, H., Tsuge, I., Okamura, T., Kawa, K., and Morishima, T. 2001. Clinical and virologic characteristics of chronic active Epstein-Barr virus infection. Blood 98: 280286.
  • 32
    Klein, G., and Purtilo, D. 1981. Summary: symposium on Epstein-Barr virus-induced lymphoproliferative diseases in immunodeficient patients. Cancer Res. 41: 43024304.
  • 33
    Knowles, D.M., Cesarman, E., Chadburn, A., Frizzera, G., Chen, J., Rose, E.A., and Michler, R.E. 1995. Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders. Blood 85: 552565.
  • 34
    Kulwichit, W., Edwards, R.H., Davenport, E.M., Baskar, J.F., Godfrey, V., and Raab Traub, N. 1998. Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 95: 1196311968.
  • 35
    Magana, M., Sangueza, P., Gil Beristain, J., Sanchez Sosa, S., Salgado, A., Ramon, G., and Sangueza, O.P. 1998. Angiocentric cutaneous T-cell lymphoma of childhood (hydroa-like lymphoma): a distinctive type of cutaneous T-cell lymphoma. J. Am. Acad. Dermatol. 38: 574579.
  • 36
    McKinsey, T.A., Brockman, J.A., Scherer, D.C., Al Murrani, S.W., Green, P.L., and Ballard, D.W. 1996. Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB. Mol. Cell Biol. 16: 20832090.
  • 37
    Mosialos, G., Birkenbach, M., Yalamanchili, R., VanArsdale, T., Ware, C., and Kieff, E. 1985. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80: 389399.
  • 38
    Nagata, H., Konno, A., Kimura, N., Zhang, Y., Kimura, M., Demachi, A., Sekine, T., Yamamoto, K., and Shimizu, N. 2001. Characterization of novel natural killer (NK)-cell and gammadelta T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus. Blood 97: 708713.
  • 39
    Nagata, H., Numata, T., Konno, A., Mikata, I., Kurasawa, K., Hara, S., Nishimura, M., Yamamoto, K., and Shimizu, N. 2001. Presence of natural killer-cell clones with variable proliferative capacity in chronic active Epstin-Barr virus infection. Pathol. Int. 51: 778785.
  • 40
    Oono, T., Arata, J., Masuda, T., and Ohtsuki, Y. 1986. Coexistence of hydroa vacciniforme and malignant lymphoma. Arch. Dermatol. 122: 13061309.
  • 41
    Raab Traub, N., and Flynn, K. 1986. The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell 47: 883889.
  • 42
    Rickinson, A.B., Murray, R.J., Brooks, J., Griffin, H., Moss, D.J., Masucci, M.G. 1992. T cell recognition of Epstein-Barr virus associated lymphomas. Cancer Surv. 13: 5380.
  • 43
    Ruiz Maldonado, R., Parrilla, F.M., Orozco Covarrubias, M.L., Ridaura, C., Tamayo, S.L., and Duran, M.C. 1995. Edematous, scarring vasculitic panniculitis: a new multisystemic disease with malignant potential. J. Am. Acad. Dermatol. 32: 3744.
  • 44
    Shearer, W.T., Ritz, J., Finegold, M.J., Guerra, I.C., Rosenblatt, H.M., Lewis, D.E., Pollack, M.S., Taber, L.H., Sumaya, C.V., Grumet, F.C., Cleary, M.L., Warnke, R., and Sklar, J. 1985. Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency. N. Engl. J. Med. 312: 11511159.
  • 45
    Shibata, D., and Weiss, L.M. 1992. Epstein-Barr virus-associated gastric adenocarcinoma. Am. J. Pathol. 140: 769774.
  • 46
    Sonnex, T.S., and Hawk, J.L. 1988. Hydroa vacciniforme: a review of ten cases. Br. J. Dermatol. 118: 101108.
  • 47
    Sugamura, K., Asao, H., Kondo, M., Tanaka, N., Ishii, N., Ohbo, K., Nakamura, M., and Takeshita, T. 1996. The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu. Rev. Immunol. 14: 179205.
  • 48
    Tabata, N., Aiba, S., Ichinohazama, R., Kikuchi, K., Aoyama, H., Watanabe, M., and Tagami, H. 1995. Hydroa vacciniforme-like lymphomatoid papulosis in a Japanese child: a new subset. J. Am. Acad. Dermatol. 32: 378381.
  • 49
    Tokura, Y., Ishihara, S., Ohshima, K., Hidano, A., Koide, M., Seo, N., and Takigawa, M. 1998. Severe mosquito bite hypersensitivity, natural killer cell leukaemia, latent or chronic active Epstein-Barr virus infection and hydroa vacciniforme-like eruption [letter]. Br. J. Dermatol. 138: 905906.
  • 50
    Tsuchiyama, J., Yoshino, T., Mori, M., Kondoh, E., Oka, T., Akagi, T., Hiraki, A., Nakayama, H., Shibuya, A., Ma, Y., Kawabata, T., Okada, S., and Harada, M. 1998. Characterization of a novel human natural killer-cell line (NK-YS) established from natural killer cell lymphoma/leukemia associated with Epstein-Barr virus infection. Blood 92: 13741383.
  • 51
    Van Gorp, J., Brink, A., Oudejans, J.J., Van Brule, A.J., Van Tweel, J.G., Jiwa, N.M., De Bruin, P.C., and Meijer, C.J. 1996. Expression of Epstein-Barr virus encoded latent genes in nasal T cell lymphomas. J. Clin. Pathol. 49: 7276.
  • 52
    Weiss, L.M., Movahed, L.A., Warnke, R.A., and Sklar, J. 1989. Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease. N. Engl. J. Med. 320: 502506.
  • 53
    Xu, X., Kang, S.H., Heidenreich, O., Okerholm, M., O'Shea, J.J., and Nerenberg, M.I. 1995. Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells. J. Clin. Invest. 96: 15481555.
  • 54
    Yoshioka, M., Ishiguro, N., Ishiko, H., Ma, X., Kikuta, H., and Kobayashi, K. 2001. Heterogeneous, restricted patterns of Epstein-Barr virus (EBV) latent gene expression in patients with chronic active EBV infection. J. Gen. Virol. 82: 23852392.
  • 55
    Zhang, Y., Nagata, H., Ikeuchi, T., Mukai, H., Oyoshi, M.K., Demachi, A., Morio, T., Wakiguchi, H., Kimura, N., Shimizu, N., Yamamoto, K. 2003. Common cytological and cytogenetic features of Epstein-Barr virus (EBV)-positive natural killer (NK) cells and cell lines derived from patients with nasal T/NK-cell lymphomas, chronic active EBV infection and hydroa vacciniforme-like eruptions. Br. J. Hematol. 121: 805814.
  • 56
    Ziegler, J.L., Drew, W.L., Miner, R.C., Mintz, L., Rosenbaum, E., Gershow, J., Lennette, E.T., Greenspan, J., Shillitoe, E., Beckstead, J., Casavant, C., and Yamamoto, K. 1982. Outbreak of Burkitt's-like lymphoma in homosexual men. Lancet 2: 631633.
  • 57
    Zur Hausen, H., Schulte Holthausen, H., Klein, G., Henle, W., Henle, G., Clifford, P., and Santesson, L. 1970. EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 228: 10561058.