Serological response against Mycobacterium avium complex glycolipid antigens in patients with acquired immunodeficiency syndrome


Dr. Toshio Hattori, Division of Infectious and Respiratory and Diseases, Postgraduate Division – Tohoku University, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan. Tel: +81-22-717-8220; fax: +81-22-717-8221; email:


In 43 MAC infected patients (23 non-HIV and 20 AIDS) the IgG response against 3 BCG and 2 MAC antigens was assessed. The response to four antigens in patients with AIDS was considerably lower than in non-HIV infected patients. Therefore, antibody production against MAC glycolipid antigens was impaired in AIDS patients.