• 1
    Tordo N., Poch O., Ermine A., Keith G., Rougeon F. (1986) Walking along the rabies genome: is the large G-L intergenic region a remnant gene? Proc Natl Acad Sci USA 83: 39148.
  • 2
    Wunner W.H. (2007) Rabies virus. In: JacksonA.C., WunnerW.H., eds. Rabies. USA : Elsevier Science, pp. 2368.
  • 3
    Finke S., Conzelmann K.K. (2003) Dissociation of rabies virus matrix protein functions in regulation of viral RNA synthesis and virus assembly. J Virol 77: 1207482.
  • 4
    Mebatsion T., Weiland F., Conzelmann K.K. (1999) Matrix protein of rabies virus is responsible for the assembly and budding of bullet-shaped particles and interacts with the transmembrane spike glycoprotein G. J Virol 73: 24250.
  • 5
    Gaudin Y., Ruigrok R.W., Tuffereau C., Knossow M., Flamand A. (1992) Rabies virus glycoprotein is a trimer. Virology 187: 62732.
  • 6
    Wunner W.H., Reagan K.J., Koprowski H. (1984) Characterization of saturable binding sites for rabies virus. J Virol 50: 6917.
  • 7
    Dietzschold B., Wunner W.H., Wiktor T.J., Lopes A.D., Lafon M., Smith C.L., Koprowski H. (1983) Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus. Proc Natl Acad Sci USA 80: 704.
  • 8
    Ito N., Takayama M., Yamada K., Sugiyama M., Minamoto N. (2001) Rescue of rabies virus from cloned cDNA and identification of the pathogenicity-related gene: glycoprotein gene is associated with virulence for adult mice. J Virol 75: 91218.
  • 9
    Morimoto K., Hooper D.C., Spitsin S., Koprowski H., Dietzschold B. (1999) Pathogenicity of different rabies virus variants inversely correlates with apoptosis and rabies virus glycoprotein expression in infected primary neuron cultures. J Virol 73: 5108.
  • 10
    Seif I., Coulon P., Rollin P.E., Flamand A. (1985) Rabies virulence: effect on pathogenicity and sequence characterization of rabies virus mutations affecting antigenic site III of the glycoprotein. J Virol 53: 92634.
  • 11
    Takayama-Ito M., Inoue K., Shoji Y., Inoue S., Iijima T., Sakai T., Kurane I., Morimoto K. (2006) A highly attenuated rabies virus HEP-Flury strain reverts to virulent by single amino acid substitution to arginine at position 333 in glycoprotein. Virus Res 119: 20815.
  • 12
    Tuffereau C., Leblois H., Bénéjean J., Coulon P., Lafay F., Flamand A. (1989) Arginine or lysine in position 333 of ERA and CVS glycoprotein is necessary for rabies virulence in adult mice. Virology 172: 20612.
  • 13
    Dietzschold B., Wiktor T.J., Trojanowski J.Q., Macfarlan R.I., Wunner W.H., Torres-Anjel M.J., Koprowski H. (1985) Differences in cell-to-cell spread of pathogenic and apathogenic rabies virus in vivo and in vitro. J Virol 56: 128.
  • 14
    Jackson A.C., Rasalingam P., Weli S.C. (2006) Comparative pathogenesis of recombinant rabies vaccine strain SAD-L16 and SAD-D29 with replacement of Arg333 in the glycoprotein after peripheral inoculation of neonatal mice: less neurovirulent strain is a stronger inducer of neuronal apoptosis. Acta Neuropathol 111: 3728.
  • 15
    Ishikawa Y., Motohashi T., Nunoya T., Nomura Y., Nomura Y. (1989) Biological properties of the cell culture adapted RC-HL strain of rabies virus as a candidate strain for an inactivated vaccine. J Jpn Vet Med Assoc 42: 63743.
  • 16
    Ito H., Minamoto N., Watanabe T., Goto H., Rong L.T., Sugiyama M., Kinjo T., Mannen K., Mifune K., Konobe T. (1994) A unique mutation of glycoprotein gene of the attenuated RC-HL strain of rabies virus, a seed virus used for production of animal vaccine in Japan. Microbiol Immunol 38: 47982.
  • 17
    Ito N., Kakemizu M., Ito K.A., Yamamoto A., Yoshida Y., Sugiyama M., Minamoto N. (2001) A comparison of complete genome sequences of the attenuated RC-HL strain of rabies virus used for production of animal vaccine in Japan, and the parental Nishigahara strain. Microbiol Immunol 45: 518.
  • 18
    Takayama-Ito M., Ito N., Yamada K., Sugiyama M., Minamoto N. (2006) Multiple amino acids in the glycoprotein of rabies virus are responsible for pathogenicity in adult mice. Virus Res 115: 16975.
  • 19
    Minamoto N., Tanaka H., Hishida M., Goto H., Ito H., Naruse S., Yamamoto K., Sugiyama M., Kinjo T., Mannen K. (1994) Linear and conformation-dependent antigenic sites on the nucleoprotein of rabies virus. Microbiol Immunol 38: 44955.
  • 20
    Luo T.R., Minamoto N., Hishida M., Yamamoto K., Fujise T., Hiraga S., Ito N., Sugiyama M., Kinjo, T. (1998) Antigenic and functional analyses of glycoprotein of rabies virus using monoclonal antibodies. Microbiol Immunol 42: 18793.
  • 21
    Préhaud C., Lay S., Dietzschold B., Lafon M. (2003) Glycoprotein of nonpathogenic rabies viruses is a key determinant of human cell apoptosis. J Virol 77: 1053747.
  • 22
    Sarmento L., Li X.Q., Howerth E., Jackson A.C., Fu Z.F. (2005) Glycoprotein-mediated induction of apoptosis limits the spread of attenuated rabies viruses in the central nervous system of mice. J Neurovirol 11: 57181.
  • 23
    Faber M., Pulmanausahakul R., Hodawadekar S.S., Spitsin S., McGettigan J.P., Schnell M.J., Dietzschold B. (2002) Overexpression of the rabies virus glycoprotein results in enhancement of apoptosis and antiviral immune response. J Virol 76: 337481.
  • 24
    Faber M., Faber M.L., Papaneri A., Bette M., Weihe E., Dietzschold B., Schnell M.J. (2005) A single amino acid change in rabies virus glycoprotein increases virus spread and enhances virus pathogenicity. J Virol 79: 141418.
  • 25
    Faber M., Pulmanausahakul R., Nagao K., Prosniak M., Rice A.B., Koprowski H., Schnell M.J., Dietzschold B. (2004) Identification of viral genomic elements responsible for rabies virus neuroinvasiveness. Proc Natl Acad Sci USA 101: 1632832.
  • 26
    Takayama-Ito M., Ito N., Yamada K., Minamoto N., Sugiyama M. (2004) Region at amino acids 164 to 303 of the rabies virus glycoprotein plays an important role in pathogenicity for adult mice. J Neurovirol 10: 1315.