Prevalence of integrons and a new dfrA17 variant in Gram-negative bacilli which cause community-acquired infections

Authors

  • Cemal Sandalli,

    1. Microbiology & Molecular Biology Research Laboratory, Department of Biology, Faculty of Arts & Sciences, Rize University, 53100 Rize
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  • Celal Kurtulus Buruk,

    1. Department of Medical Microbiology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon
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  • Metin Sancaktar,

    Corresponding author
    1. Clinical Microbiology Laboratory, 82nd Year of Government General Hospital, 53000 Rize
      Current address: Clinical Microbiology Laboratory, Fatih Devlet Hastanesi, 61000 Trabzon, Turkey.
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  • Osman Birol Ozgumus

    1. Microbiology & Molecular Biology Research Laboratory, Department of Biology, Faculty of Arts & Sciences, Rize University, 53100 Rize
    2. Department of Medical Microbiology, Faculty of Medicine, Rize University, 53100 Rize, Turkey
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Current address: Clinical Microbiology Laboratory, Fatih Devlet Hastanesi, 61000 Trabzon, Turkey.

Correspondence
Osman Birol Ozgumus, Rize Universitesi, Tip Fakultesi, Tibbi Mikrobiyoloji Anabilim Dali, Islampasa Mah., 53100 Rize, Turkey. Tel: +90 464 212 30 09; fax: +90 464 212 30 15; email: microbsman@yahoo.com

ABSTRACT

A hundred and eleven Gram-negative bacilli from community-acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E. coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics (P < 0.05).

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