Detection and identification of non-Candida albicans species in human oral lichen planus
Article first published online: 22 DEC 2010
© 2010 The Societies and Blackwell Publishing Asia Pty Ltd
Microbiology and Immunology
Volume 55, Issue 1, pages 66–70, January 2011
How to Cite
Masaki, M., Sato, T., Sugawara, Y., Sasano, T. and Takahashi, N. (2011), Detection and identification of non-Candida albicans species in human oral lichen planus. Microbiology and Immunology, 55: 66–70. doi: 10.1111/j.1348-0421.2010.00285.x
- Issue published online: 22 DEC 2010
- Article first published online: 22 DEC 2010
- Accepted manuscript online: 11 NOV 2010 04:00AM EST
- Received 11 August 2010; revised 8 October 2010; accepted 28 October 2010.
- oral lichen planus;
- polymerase chain reaction
Candida species were detected and identified in samples from the buccal mucosa, dorsal surface of the tongue and supragingival plaque of subjects with oral lichen planus (OLP). The Candida in the samples were cultured on selection agars, and identified by sequence analyses of 18S, 5.8S and 25/28S rRNA. The isolation frequency of Candida was higher in subjects with OLP than in those with healthy oral mucosa. Non-C. albicans were only isolated from people with OLP. These results support the notion that subjects with OLP are more likely to have oral colonization with Candida, and that non-C. albicans are specifically present in subjects with this condition.