• 1
    Ikeda R., Saito F., Matsuo M., Kurokawa K., Sekimizu K., Yamaguchi M., Kawamoto S. (2007) Contribution of the mannan backbone of cryptococcal glucuronoxylomannan and a glycolytic enzyme of Staphylococcus aureus to contact-mediated killing of Cryptococcus neoformans. J Bacteriol 189: 48154826.
  • 2
    Furuya H., Ikeda R. (2009) Interaction of triosephosphate isomerase from the cell surface of Staphylococcus aureus and alpha-(1->3)-mannooligosaccharides derived from glucuronoxylomannan of Cryptococcus neoformans. Microbiology 155: 27072713.
  • 3
    Patti J.M., Allen B.L., McGavin M.J., Hook M. (1994) MSCRAMM-mediated adherence of microorganisms to host tissues. Annu Rev Microbiol 48: 585617.
  • 4
    Pancholi V., Fischetti V.A. (1992) A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity. J Exp Med 176: 415426.
  • 5
    Pancholi V., Chhatwal G.S. (2003) Housekeeping enzymes as virulence factors for pathogens. Int J Med Microbiol 293: 391401.
  • 6
    Bergmann S., Hammerschmidt S. (2006) Versatility of pneumococcal surface proteins. Microbiology 152: 295303.
  • 7
    Bergmann S., Rohde M., Hammerschmidt S. (2004) Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pneumoniae is a surface-displayed plasminogen-binding protein. Infect Immun 72: 24162419.
  • 8
    Ling E., Feldman G., Portnoi M., Dagan R., Overweg K., Mulholland F., Chalifa-Caspi V., Wells J., Mizrachi-Nebenzahl Y. (2004) Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse. Clin Exp Immunol 138: 290298.
  • 9
    Egea L., Aguilera L., Gimenez R., Sorolla M.A., Aguilar J., Badia J., Baldoma L. (2007) Role of secreted glyceraldehyde-3-phosphate dehydrogenase in the infection mechanism of enterohemorrhagic and enteropathogenic Escherichia coli: interaction of the extracellular enzyme with human plasminogen and fibrinogen. Int J Biochem Cell Biol 39: 11901203.
  • 10
    Crowe J.D., Sievwright I.K., Auld G.C., Moore N.R., Gow N.A., Booth N.A. (2003) Candida albicans binds human plasminogen: identification of eight plasminogen-binding proteins. Mol Microbiol 47: 16371651.
  • 11
    Bergmann S., Rohde M., Chhatwal G.S., Hammerschmidt S. (2001) alpha-Enolase of Streptococcus pneumoniae is a plasmin(ogen) binding protein displayed on the bacterial cell surface. Mol Microbiol 40: 12731287.
  • 12
    Bergmann S., Wild D., Diekmann O., Frank R., Bracht D., Chhatwal G.S., Hammerschmidt S. (2003) Identification of a novel plasmin(ogen)-binding motif in surface displayed alpha-enolase of Streptococcus pneumoniae. Mol Microbiol 49: 411423.
  • 13
    Bergmann S., Rohde M., Preissner, K.T., Hammerschmidt S. (2005) The nine residue plasminogen-binding motif of the pneumococcal enolase is the major cofactor of plasmin-mediated degradation of extracellular matrix, dissolution of fibrin and transmigration. Thromb Haemost 94: 304311.
  • 14
    Derbise A., Song Y.P., Parikh S., Fischetti V.A., Pancholi V. (2004) Role of the C-terminal lysine residues of streptococcal surface enolase in Glu- and Lys-plasminogen-binding activities of group A streptococci. Infect Immun 72: 94105.
  • 15
    Ehinger S., Schubert W.D., Bergmann S., Hammerschmidt S., Heinz D.W. (2004) Plasmin(ogen)-binding alpha-enolase from Streptococcus pneumoniae: crystal structure and evaluation of plasmin(ogen)-binding sites. J Mol Biol 343: 9971005.
  • 16
    Kolberg J., Aase A., Bergmann S., Herstad T.K., Rodal G., Frank R., Rohde M., Hammerschmidt S. (2006) Streptococcus pneumoniae enolase is important for plasminogen binding despite low abundance of enolase protein on the bacterial cell surface. Microbiology 152: 13071317.
  • 17
    Esgleas M., Li Y., Hancock M.A., Harel J., Dubreuil J.D., Gottschalk M. (2008) Isolation and characterization of alpha-enolase, a novel fibronectin-binding protein from Streptococcus suis. Microbiology 154: 26682679.
  • 18
    Pereira L.A., Bao S.N., Barbosa M.S., da Silva J.L., Felipe M.S., de Santana J.M., Mendes-Giannini M.J., de Almeida Soares C.M. (2007) Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function. FEMS Yeast Res 7: 13811388.
  • 19
    Ribeiro de Jesus A., Araújo I., Bacellar O., Magalhães A., Pearce E., Harn D., Strand M., Carvalho E.M. (2000) Human immune responses to Schistosoma mansoni vaccine candidate antigens. Infect Immun 68: 27972803.
  • 20
    Gatlin C.L., Pieper R., Huang S.T., Mongodin E., Gebregeorgis E., Parmar P.P., Clark D.J., Alami H., Papazisi L., Fleischmann R.D., Gill S.R., Peterson S.N. (2006) Proteomic profiling of cell envelope-associated proteins from Staphylococcus aureus. Proteomics 6: 15301549.
  • 21
    Yamaguchi M., Ikeda R., Nishimura M., Kawamoto S. (2010) Localization by scanning immunoelectron microscopy of triosephosphate isomerase, the molecules responsible for contact-mediated killing of Cryptococcus, on the surface of Staphylococcus. Microbiol Immunol 54: 368370.
  • 22
    Hall R.A. (2004) Studying protein–protein interactions via blot overlay or Far Western blot. Methods Mol Biol 261: 167174.
  • 23
    Gil-Navarro I., Gil M.L., Casanova M., O’Connor J.E., Martínez J.P., Gozalbo D. (1997) The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase of Candida albicans is a surface antigen. J Bacteriol 179: 49924999.
  • 24
    Harraghy N., Hussain M., Haggar A., Chavakis T., Sinha B., Herrmann M., Flock J.I. (2003) The adhesive and immunomodulating properties of the multifunctional Staphylococcus aureus protein Eap. Microbiology 149: 27012707.
  • 25
    Bergmann S., Hammerschmidt S. (2007) Fibrinolysis and host response in bacterial infections. Thromb Haemost 98: 512520.
  • 26
    Gase K., Gase A., Schirmer H., Malke H. (1996) Cloning, sequencing and functional overexpression of the Streptococcus equisimilis H46A gapC gene encoding a glyceraldehyde-3-phosphate dehydrogenase that also functions as a plasmin(ogen)-binding protein. Purification and biochemical characterization of the protein. Eur J Biochem 239: 4251.
  • 27
    Seifert K.N., McArthur W.P., Bleiweis A.S., Brady L.J. (2003) Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein–protein interactions. Can J Microbiol 49: 350356.
  • 28
    Gozalbo D., Gil-Navarro I., Azorin I., Renau-Piqueras J., Martinez J.P., Gil M.L. (1998) The cell wall-associated glyceraldehyde-3-phosphate dehydrogenase of Candida albicans is also a fibronectin and laminin binding protein. Infect Immun 66: 20522059.
  • 29
    Carneiro C.R., Postol E., Nomizo R., Reis L.F., Brentani R.R. (2004) Identification of enolase as a laminin-binding protein on the surface of Staphylococcus aureus. Microbes Infect 6: 604608.
  • 30
    Antikainen J., Kuparinen V., Lahteenmaki K., Korhonen, T.K. (2007) Enolases from Gram-positive bacterial pathogens and commensal lactobacilli share functional similarity in virulence-associated traits. FEMS Immunol Med Microbiol 51: 526534.
  • 31
    Saito F., Ikeda R. (2005) Killing of Cryptococcus neoformans by Staphylococcus aureus: the role of cryptococcal capsular polysaccharide in the fungal–bacteria interaction. Med Mycol 43: 603612.
  • 32
    Ikeda R., Sawamura K. (2008) Bacterial and H2O2 stress-induced apoptosis-like events in Cryptococcus neoformans. Res Microbiol 159: 628634.
  • 33
    Molkanen T., Tyynela J., Helin J., Kalkkinen N., Kuusela P. (2002) Enhanced activation of bound plasminogen on Staphylococcus aureus by staphylokinase. FEBS Lett 517: 7278.
  • 34
    Glowalla E., Tosetti B., Kronke M., Krut O. (2009) Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus. Infect Immun 77: 27192729.
  • 35
    Cork A.J., Jergi S., Hammerschmidt S., Kobe B., Pancholi V., Benesch J.L.P., Robinson C.V., Dixon N.E., Aquilina J.A., Walker M.J. (2009) Defining the structural basis of human plasminogen binding by streptococcal surface enolase. J Biol Chem 284: 1712917137.
  • 36
    Walker M.J., McArthur J.D., McKay F., Ranson M. (2005) Is plasminogen deployed as a Streptococcus pyogenes virulence factor? Trends Microbiol 13: 308313.
  • 37
    Attali C., Durmort C., Vernet T., Di Guilmi A.M. (2008) The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junction cleavage. Infect Immun 76: 53505356.
  • 38
    Attali C., Frolet C., Durmort C., Offant J., Vernet T., Di Guilmi, A.M. (2008) Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix. Infect Immun 76: 466476.
  • 39
    Kuusela P., Saksela O. (1990) Binding and activation of plasminogen at the surface of Staphylococcus aureus. Increase in affinity after conversion to the Lys form of the ligand. Eur J Biochem 193: 759765.
  • 40
    Niemann S., Spehr N., Van Aken H., Morgenstern E., Peters G., Herrmann M., Kehrel B.E. (2004) Soluble fibrin is the main mediator of Staphylococcus aureus adhesion to platelets. Circulation 110: 193200.
  • 41
    Henderson B., Martin A. (2011) Bacterial virulence in the moonlight: multitasking bacterial moonlighting proteins are virulence determinants in infectious disease. Infect Immun 79: 34763491.