SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    ) Takeichi , M. Cadherin cell adhesion receptor as a mor–phogenetic regulator . Science , 251 , 14511455 ( 1991 ).
  • 2
    ) Behrens , J. , Mareel , M. M. , Van Roy , F. M. , and Birchmeier , W. Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin–mediated cell–cell adhesion . J. Cell Biol , 108 , 24352447 ( 1989 ).
  • 3
    ) Vleminckx , K. , Vakaet , L. , Jr. , Mareel , M. , Fiers , W. and Van Roy , F. Genetic manipulation of E–cadherin expression by epithelial tumor cells reveals an invasion suppressor role . Cell , 66 , 107119 ( 1991 ).
  • 4
    ) Frixen , U. H. , Behrens , J. , Sachs , M. , Eberle , G. , Voss , B. , Warda , A. , Lochner , D. and Birchmeier , W. E–Cadherin–mediated cell–cell adhesion prevents invasiveness of human carcinoma cells . J Cell Biol. , 113 , 173185 ( 1991 ).
  • 5
    ) Shimoyama , Y. and Hirohashi , S. Expression of E– and P–cadherin in gastric carcinoma . Cancer Res. , 51 , 21852192 ( 1991 ).
  • 6
    ) Oka , H. , Shiozaki , H. , Kobayashi , K. , Tahara , H. , Tamura , S. , Miyata , M. , Doki , Y. , Lihara , K. , Matsuyoshi , N. , Hirano , S. , Takeichi , M. and Mori , T. Immunohisto–chemical evaluation of E–cadherin adhesion molecule expression in human gastric cancer . Virchotvs Arch. A , 421 , 149156 ( 1992 ).
  • 7
    ) Mayer , B. , Johnson , J. P. , Leitl , F. , Jauch , K. W. , Heiss , M. M. , Schidberg , F. W. , Birchmeier , W. and Funke I. E–Cadherin expression in primary and metastatic gastric cancer: down–regulation correlates with cellular differentiation and glandular disintegration . Cancer Res. , 53 , 16901695 ( 1993 ).
  • 8
    ) Ochiai , A. , Akimoto , S. , Shimoyama , Y. , Nagafuchi , A. , Tsukita , S. and Hirohashi , S. Frequent loss of a catenin expression in scirrhous carcinomas with scattered cell growth . Jpn. J. Cancer Res. , 85 , 266273 ( 1994 ).
  • 9
    ) Shimoyama , Y. , Hirohashi , S. , Hirano , S. , Noguchi , M. , Shimosato , Y. , Takeichi , M. and Abe , O. Cadherin cell–adhesion molecules in human epithelial tissue and carcinomas . Cancer Res. , 49 , 21282133 ( 1989 ).
  • 10
    ) Shimoyama , Y. and Hirohashi , S. Cadherin intercellular adhesion molecule in hepatocellular carcinoma: loss of E–cadherin expression in an undifferentiated carcinoma . Cancer Lett. , 57 , 131135 ( 1991 ).
  • 11
    ) Schipper , J. H. , Frixen , H. U. , Behrens , J. , Unger , A. , Jahnke , K. and Birchmeier , W. E–Cadherin expression in squamous cell carcinoma of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis . Cancer Res. , 51 , 63286337 ( 1991 ).
  • 12
    ) Shiozaki , H. , Tahara , H. , Oka , H. , Miyata , M. , Kobayashi , K. , Tamura , S. , Lihara , K. , Doki , Y. , Hirano , S. , Takeichi , M. and Mori , T. Expression of immunoreactive E–cadherin adhesion molecules in human cancers . Am. J. Pathol , 139 , 1723 ( 1991 ).
  • 13
    ) Umbas , R. , Schalken , J. , Aalders , T. W. , Carter , B. S. , Karthaus , H. F. M. , Schaafsma , H. E. , Debruyne , F. M. J. and Isaacs , W. B. Expression of the cellular adhesion molecule E–cadherin is reduced or absent in high–grade prostate cancer . Cancer Res. , 52 , 51045109 ( 1992 ).
  • 14
    ) Rasbridge , S. A. , Gillett , C. E. , Sampson , S. A. , Walsh , F. S. and Millis , R. R. Epithelial (E–) and placental (P–) cadherin cell adhesion molecule expression in breast carcinoma . J. Pathol. , 169 , 245250 ( 1993 ).
  • 15
    ) Oda , T. , Kanai , Y. , Oyama , T. , Yoshiura , K. , Shimoyama , Y. , Birchmeier , W. , Sugimura , T. and Hirohashi , S. E–Cadherin gene mutations in human gastric carcinoma cell lines . Proc. Natl. Acad. SO. USA. 91 , 18581862 ( 1994 ).
  • 16
    ) Ringwald , M. , Baribault , H. , Schkidt , C. and Kemler , R. The structure of the gene coding for the mouse cell adhesion molecule uvomorulin . Nucleic Acids Res. , 19 , 65336539 ( 1991 ).
  • 17
    ) Nose , A. , Tsuji , K. and Takeichi , M. Localization of specific determining sites in cadherin cell adhesion molecules . Cell , 61 , 147155 ( 1990 ).
  • 18
    ) Warner , N. E. Lobular carcinoma of the breast . Cancer , 23 , 840846 ( 1969 ).
  • 19
    ) Sambrook , J. , Fritsch , E. F. and Maniatis , T. Molecular Cloning: A Laboratory Manual, ” pp. E.3E.4 ( 1989 ). Cold Spring Harbor Lab. , Cold Spring Harbor , NY .
  • 20
    ) Suzuki , Y. , Sekiya , T. and Hayashi , K. Allele–speciflc polymerase chain reaction: a method for amplification and sequence determination of a single component among a mixture of sequence variants . Anal. Biochem. , 192 , 8284 ( 1991 ).
  • 21
    ) Sato , Y. , Mukai , K. , Watanabe , S. , Goto , M. and Shimosato , Y. The AMeX method: a simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining . Am. J. Pathol. , 125 , 431435 ( 1986 ).
  • 22
    ) Lauren , P. The two histological main types of gastric carcinoma: diffuse and so–called intestinal–type carcinoma . Ada Pathol Microbiol. Scand. , 64 , 3149 ( 1965 ).
  • 23
    ) Nagafuchi , A. , Takeichi , M. and Tsukita , S. The 102 kd cadherin–associated protein: similarity to vinculin and post–transcriptional regulation of expression . Cell , 65 , 849857 ( 1991 ).
  • 24
    ) Maquat , L. E. , Kinniburgh , A. J. , Rachmilewitz , E. A. and Ross , J. Unstable β–globin mRNA in mRNA–deficient β0 thalassemia . Cell , 27 , 543553 ( 1981 ).
  • 25
    ) Belasco , J. G. and Higgins , C. F. Mechanisms of mRNA decay in bacteria: a perspective . Gene , 72 , 1523 ( 1988 ).
  • 26
    ) Oda , T. , Kanai , Y. , Shimoyama , Y. , Nagafuchi , A. , Tsukita , S. and Hirohashi , S. Cloning of the human a–catenin cDNA and its aberrant mRNA in a human cancer cell line . Biochem. Biophys. Res. Commun. , 193 , 897904 ( 1993 ).
  • 27
    ) Ozawa , M. , Engel , J. and Kemler , R. Single ammo acid substitution in one Ca2+ binding site of uvomorulin abolishes the adhesion function . Cell , 63 , 10331038 ( 1990 ).
  • 28
    ) Mansouri , A. , Spurr , N. , Goodfellow , P. N. and Kemler , R. Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin . Differentiation , 38 , 6771 ( 1988 ).
  • 29
    ) Sato , T. , Tanigami , A. , Yamakawa , K. , Akiyama , F. , Kasumi , F. , Sakamoto , G. and Nakamura , Y. Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer . Cancer Res. , 50 , 71847189 ( 1990 ).
  • 30
    ) Sato , T. , Akiyama , P. , Sakamoto , G. , Kasumi , F. and Nakamura , Y. Accumulation of genetic alteration and progression of primary breast cancer . Cancer Res. , 51 , 57945799 ( 1991 ).