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REFERENCES

  • 1
    ) Kadomatsu , K. , Tomomura , M. and Muramatsu , T. cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis . Biochem. Biophys. Res. Commun. , 151 , 13121318 ( 1988 ).
  • 2
    ) Tomomura , M. , Kadomatsu , K. , Matsubara , S. and Muramatsu , T. A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product . J. Biol. Chem. , 265 , 1076510770 ( 1990 ).
  • 3
    ) Muramatsu , T. Midkine (MK), the product of a retinoic acid responsive gene, and pleiotrophin constitute a new protein family regulating growth and differentiation . Int. J. Dev. Biol. , 37 , 183188 ( 1993 ).
  • 4
    ) Merenmies , J. and Rauvala , H. Molecular cloning of the 18kDa growth-associated protein of developing brain . J. Biol. Chem. , 265 , 1672116724 ( 1990 ).
  • 5
    ) Li , Y. S. , Milner , P. G. , Chauhan , A. K. , Watson , M. A. , Hoffman , R. M. , Kodner , C. M. , Milbrandt , J. and Deuel , T. F. Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity . Science , 250 , 16901694 ( 1990 ).
  • 6
    ) Muramatsu , H. and Muramatsu , T. Purification of recombinant midkine and examination of its biological activities: functional comparison of new heparin binding factors . Biochem. Biophys. Res. Commun. , 177 , 652658 ( 1991 ).
  • 7
    ) Nurcombe , V. , Eraser , N. , Herlaar , E. and Heath , J. K. MK, a pluripotential embryonic stem cell-derived neuroregulatory factor . Development , 116 , 11751183 ( 1992 ).
  • 8
    ) Michikawa , M. , Kikuchi , S. , Muramatsu , H. , Muramatsu , T. and Kim , S. U. Retinoic acid responsive gene product, midkine (MK), has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture . J. Neurosci. Res. , 35 , 530539 ( 1993 ).
  • 9
    ) Satoh , J. , Muramatsu , H. , Moretto , G. , Muramatsu , T. , Chang , H. J. , Kim , S. T. , Cho , J. M. and Kim , S. U. Midkine that promotes survival of human neurons is produced by fetal human astrocytes in culture . Dev. Brain Res. , 75 , 201205 ( 1993 ).
  • 10
    ) Muramatsu , H. , Shirahama , H. , Yonezawa , S. , Maruta , H. and Muramatsu , T. Midkine, a retinoic acid-inducible growth/differentiation factor: immunochemical evidence for the function and distribution . Dev. Biol. , 159 , 392402 ( 1993 ).
  • 11
    ) Heldin , C.-H. and Westermark , B. Growth factors as transforming proteins . Eur. J. Biochem. , 184 , 487496 ( 1989 ).
  • 12
    ) Aaronson , S. A. Growth factors and cancer . Science , 254 , 11461153 ( 1991 ).
  • 13
    ) Cross , M. and Derten , T. M. Growth factors in development, transformation, and tumorigenesis . Cell , 64 , 271280 ( 1991 ).
  • 14
    ) Tsutsui , J. , Kadomatsu , K. , Matsubara , S. , Nakagawara , A. , Hamanoue , M. , Takao , S. , Shimazu , H. , Ohi , Y. and Muramatsu , T. A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas . Cancer Res. , 53 , 12811285 ( 1993 ).
  • 15
    ) Chomczynski , P. and Sacchi , N. Single step method of RNA isolation by guanidium thiocyanate-phenol-chloroform extraction . Anal. Biochem. , 162 , 156159 ( 1987 ).
  • 16
    ) Tsutsui , J. , Uehara , K. , Kadomatsu , K. , Matsubara , S. and Muramatsu , T. A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse . Biochem. Biophys. Res. Commun. , 176 , 792797 ( 1991 ).
  • 17
    ) Laemmli , U. K. Cleavage of structural protein during assembly of the head of bacteriophage T4 . Nature , 227 , 680685 ( 1970 ).
  • 18
    ) Towbin , H. , Staehelin , T. and Gordon , J. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications . Proc. Natl. Acad. Sci. USA , 76 , 43504354 ( 1977 ).
  • 19
    ) Take , M. , Tsutsui , J. , Ozawa , M. , Nakayama , T. , Arima , T. and Muramatsu , T. Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth associated molecule (HB-GAM) . J. Biochem. , 116 , 10631068 ( 1994 ).
  • 20
    ) Chauhan , A. K. , Li , Y. and Deuel , T. F. Pleiotrophin transforms NIH 3T3 cells and induces tumors in nude mice . Proc. Natl. Acad. Sci. USA , 90 , 679682 ( 1993 ).
  • 21
    ) Garver , R. I. , Chan , C. S. and Milner , P. G. Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues . Am. J. Respir. Cell Mol. Biol. , 9 , 463466 ( 1993 ).
  • 22
    ) Garver , R. I. , Radford , D. M. , Donis-Keller , H. , Wick , M. R. and Milner , P. G. Midkine and pleiotrophin expression in normal and malignant breast tissue . Cancer , 74 , 15841590 ( 1994 ).
  • 23
    ) Kadomatsu , K. , Huang , R.-P. , Suganuma , T. , Murata , F. and Muramatsu , T. A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis . J. Cell Biol. , 110 , 607616 ( 1990 ).
  • 24
    ) Yoshida , Y. , Goto , M. , Tsutsui , J. , Ozawa , M. , Sato , E. , Osame , M. and Muramatsu , T. Midkine is present in the early stage of cerebral infarct . Dev. Brain Res. , 85 , 2530 ( 1995 ).
  • 25
    ) Matsubara , S. , Take , M. , Pedraza , C. and Muramatsu , T. Mapping and characterization of a retinoic acid-responsive enhancer of midkine, a novel heparin-binding growth/differentiation factor with neurotrophic activity . J. Biochem. , 115 , 10881096 ( 1994 ).