SEARCH

SEARCH BY CITATION

REFERENCES

  • 1)
    Steck , P. A. , Pershouse , M. A. , Jasser , S. A. , Yung , W. K. A. , Lin , H. , Ligon , A. H. , Langford , L. A. , Baumgard , M. L. , Hattier , T. , Davis , T. , Frye , C. , Hu , R. , Swedlund , B. , Teng , D. H. F. and Tavtigian , S. V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers . Nat. Genet. , 15 , 356362 ( 1997 ).
  • 2)
    Li , J. , Yen , C. , Liaw , D. , Podsypanina , K. , Bose , S. , Wang , S. I. , Puc , J. , Miliaresis , C. , Rodgers , L. , McCombie , R. , Bigner , S. H. , Giovanella , B. C. , Ittmann , M. , Tycko , B. , Hibshoosh , H. , Wigler , M. H. and Parsons , R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer . Science , 275 , 19431947 ( 1997 ).
  • 3)
    Li , D.-M. and Sun , H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β . Cancer Res. , 57 , 21242129 ( 1997 ).
  • 4)
    Myers , M. P. , Stolarov , J. P. , Eng , C. , Li , J. , Wang , S. I. , Wigler , M. H. , Parsons , R. and Tonks , N. K. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase . Proc. Natl. Acad. Sci. USA , 94 , 90529057 ( 1997 ).
  • 5)
    Maehama , T. and Dixon , J. E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate . J. Biol. Chem. , 273 , 1337513378 ( 1998 ).
  • 6)
    Furnari , F. B. , Huang , H.-J. S. and Cavenee , W. K. The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells . Cancer Res. , 58 , 50025008 ( 1998 ).
  • 7)
    Wang , S. I. , Puc , J. , Li , J. , Bruce , J. N. , Cairns , P. , Sidransky , D. and Parsons , R. Somatic mutations of PTEN in glioblastoma multiforme . Cancer Res. , 57 , 41834186 ( 1997 ).
  • 8)
    Liu , W. , James , C. D. , Frederick , L. , Alderete , B. E. and Jenkins , R. B. PTEN/MMAC1 mutations and EGFR amplification in glioblastomas . Cancer Res. , 57 , 52545257 ( 1997 ).
  • 9)
    Chiariello , E. , Roz , L. , Albarosa , R. , Magnani , I. and Finocchiaro , G. PTEN/MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas . Oncogene , 16 , 541545 ( 1998 ).
  • 10)
    Rasheed , B. K. A. , Stenzel , T. T. , McLendon , R. E. , Parsons , R. , Friedman , A. H. , Friedman , H. S. , Bigner , D. D. and Bigner , S. H. PTEN gene mutations are seen in high-grade but not in low-grade gliomas . Cancer Res. , 57 , 41874190 ( 1997 ).
  • 11)
    Duerr , E.-M. , Rollbrocker , B. , Hayashi , Y. , Peters , N. , Meyer-Puttlitz , B. , Louis , D. N. , Schramm , J. , Wiestler , O. D. , Parsons , R. , Eng , C. and von Deimling , A. PTEN mutations in gliomas and glioneuronal tumors . Oncogene , 16 , 22592264 ( 1998 ).
  • 12)
    Maier , D. , Zhang , Z. , Taylor , E. , Hamou , M.-F. , Gratzl , O. , van Meir , E. G. , Scott , R. J. and Merlo , A. Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25–26 region as the primary target in low-grade and high-grade gliomas . Oncogene , 16 , 33313335 ( 1998 ).
  • 13)
    Furnari , F. B. , Lin , H. , Huang , H.-J. S. and Cavenee , W. K. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain . Proc. Natl. Acad. Sci. USA , 94 , 1247912484 ( 1997 ).
  • 14)
    Teng , D. H.-F. , Hu , R. , Lin , H. , Davis , T. , Iliev , D. , Frye , C. , Swedlund , B. , Hansen , K. L. , Vinson , V. L. , Gumpper , K. L. , Ellis , L. , El-Naggar , A. , Frazier , M. , Jasser , S. , Langford , L. A. , Lee , J. , Mills , G. B. , Pershouse , M. A. , Pollack , R. E. , Tornos , C. , Troncoso , P. , Yung , W. K. A. , Fujii , G. , Berson , A. , Bookstein , R. , Bolen , J. B. , Tavtigian , S. V. and Steck , P. A. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines . Cancer Res. , 57 , 52215225 ( 1997 ).
  • 15)
    Cairns , P. , Okami , K. , Halachmi , S. , Halachmi , N. , Esteller , M. , Herman , J. G. , Jen , J. , Isaacs , W. B. , Bova , G. S. and Sidransky , D. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer . Cancer Res. , 57 , 49975000 ( 1997 ).
  • 16)
    Suzuki , H. , Freije , D. , Nusskern , D. R. , Okami , K. , Cairns , P. , Sidransky , D. , Isaacs , W. B. and Bova , G. S. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues . Cancer Res. , 58 , 204209 ( 1998 ).
  • 17)
    Kong , D. , Suzuki , A. , Zou , T.-T. , Sakurada , A. , Kemp , L. W. , Wakatsuki , S. , Yokoyama , T. , Yamakawa , H. , Furukawa , T. , Sato , M. , Ohuchi , N. , Sato , S. , Yin , J. , Wang , S. , Abraham , J. M. , Souza , R. F. , Smolinski , K. N. , Meltzer , S. J. and Horii , A. PTEN1 is frequently mutated in primary endometrial carcinomas . Nat. Genet. , 17 , 143144 ( 1997 ).
  • 18)
    Risinger , J. I. , Hayes , A. K. , Berchuck , A. and Barrett , J. C. PTEN/MMAC1 mutations in endometrial cancers . Cancer Res. , 57 , 47364738 ( 1997 ).
  • 19)
    Tashiro , H. , Blazes , M. S. , Wu , R. , Cho , K. R. , Bose , S. , Wang , S. I. , Li , J. , Parsons , R. and Ellenson , L. H. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies . Cancer Res. , 57 , 39353940 ( 1997 ).
  • 20)
    James , C. D. , Carlbom , E. , Dumanski , J. P. , Hansen , M. , Nordenskjold , M. , Collins , V. P. and Cavenee , W. K. Clonal genomic alterations in glioma malignancy stages . Cancer Res. , 48 , 55465551 ( 1988 ).
  • 21)
    Fults , D. , Pedone , C. A. , Thomas , G. A. and White , R. Allelotype of human malignant astrocytoma . Cancer Res. , 50 , 57845789 ( 1990 ).
  • 22)
    Rasheed , B. K. A. , McLendon , R. E. , Friedman , H. S. , Friedman , A. H. , Fuchs , H. E. , Bigner , D. D. and Bigner , S. H. Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25 . Oncogene , 10 , 22432246 ( 1995 ).
  • 23)
    Kim , S. K. , Su , L.-K. , Oh , Y. , Kemp , B. L. , Hong , W. K. and Mao , L. Alterations of PTEN/MMAC1, a candidate tumour suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines . Oncogene , 16 , 8993 ( 1998 ).
  • 24)
    Dahia , P. L. M. , FitzGerald , M. G. , Zhang , X. , Marsh , D. J. , Zheng , Z. , Pietsch , T. , von Deimling , A. , Haluska , F. G. , Haber , D. A. and Eng , C. A highly conserved processed PTEN pseudogene is located on chromosome band 9p21 . Oncogene , 16 , 24032406 ( 1998 ).
  • 25)
    Zhang , S.-J. , Endo , S. , Koga , H. , Ichikawa , T. , Feng , X.-L. , Onda , K. , Washiyama , K. and Kumanishi , T. A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations . Jpn. J. Cancer Res. , 87 , 900907 ( 1996 ).
  • 26)
    Onda , K. , Tanaka , R. , Washiyama , K. , Takeda , N. and Kumanishi , T. Correlation of DNA ploidy and morphological features of human glioma cell cultures with the establishment of cell lines . Acta Neuropathol. , 76 , 433440 ( 1988 ).
  • 27)
    Onda , K. , Washiyama , K. , Tanaka , R. , Nishiyama , A. , Usui , H. and Kumanishi , T. Establishment of human glioma cell lines with stable and unstable GFAP expression . Biomed. Res. , 13 , 327334 ( 1992 ).
  • 28)
    Yamazaki , K. Tumorigenicity of established human glioma cell lines in lasat and nude mice . Neuropathology , 3 , 2938 ( 1982 ) ( in Japanese ).
  • 29)
    Bigner , D. D. , Bigner , S. H. , Ponten , J. , Westermark , B. , Mahaley , M. S. , Jr. , Ruoslahti , E. , Herschman , H. , Eng , L. F. and Wikstrand , C. J. Heterogeneity of genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas . J. Neuropathol. Exp. Neurol. 40 , 201229 ( 1981 ).
  • 30)
    Chomczynski , P. and Sacchi , N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction . Anal. Biochem. , 162 , 156159 ( 1987 ).
  • 31)
    Liaw , D. , Marsh , D. J. , Li , J. , Dahia , P. L. M. , Wang , S. I. , Zheng , Z. , Bose , S. , Call , K. M. , Tsou , H. C. , Peacocke , M. , Eng , C. and Parsons , R. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome . Nat. Genet. , 16 , 6467 ( 1997 ).
  • 32)
    Lynch , E. D. , Ostermeyer , E. A. , Lee , M. K. , Arena , J. F. , Ji , H. , Dann , J. , Swisshelm , K. , Suchard , D. , MacLeod , P. M. , Kvinnsland , S. , Gjertsen , B. T. , Heimdal , K. , Lubs , H. , Moller , P. and King , M.-C. Inherited mutations in PTEN that are associated with breast cancer, Cowden disease, and juvenile polyposis . Am. J. Hum. Genet. , 61 , 12541260 ( 1997 ).
  • 33)
    Kohno , T. , Takahashi , M. , Manda , R. and Yokota , J. Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers . Genes Chromosom. Cancer , 22 , 152156 ( 1998 ).
  • 34)
    Gronbaek , K. , Zeuthen , J. , Guldberg , P. , Ralfkiaer , E. and Hou-Jensen , K. Alterations of the MMAC1/PTEN gene in lymphoid malignancies . Blood , 19 , 43884390 ( 1998 ).
  • 35)
    FitzGerald , M. G. , Marsh , D. J. , Wahrer , D. , Bell , D. , Caron , S. , Shannon , K. E. , Ishioka , C. , Isselbacher , K. J. , Garber , J. E. , Eng , C. and Haber , D. A. Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer . Oncogene , 17 , 727731 ( 1998 ).
  • 36)
    Guldberg , P. , thor Straten , P. , Birck , A. , Ahrenkiel , V. , Kirkin , A. F. and Zeuthen , J. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma . Cancer Res. , 57 , 36603663 ( 1997 ).